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Murray's law revisited: Quémada's fluid model and fractal trees [PDF]
J. Rheol. 59, 1419 (2015), 2015 In 1926, Murray proposed the first law for the optimal design of blood vessels. He minimized the power dissipation arising from the trade-off between fluid circulation and blood maintenance. The law, based on a constant fluid viscosity, states that in the optimal configuration the fluid flow rate inside the vessel is proportional to the cube of the ...
Mauroy, Benjamin, Moreau, Baptiste
arxiv +5 more sources
Colloids and the Microcirculation
Anesthesia & Analgesia, 2017 Colloid solutions have been advocated for use in treating hypovolemia due to their expected effect on improving intravascular retention compared with crystalloid solutions. Because the ultimate desired effect of fluid resuscitation is the improvement of microcirculatory perfusion and tissue oxygenation, it is of interest to study the effects of ...
Huaiwu He, Dawei Liu, C. Ince
semanticscholar +6 more sources
Inversion of hematocrit partition at microfluidic bifurcations [PDF]
Microvasc. Research 105, 40-46 (2016), 2016 Partitioning of red blood cells (RBCs) at the level of bifurcations in the microcirculatory system affects many physiological functions yet it remains poorly understood. We address this problem by using T-shaped microfluidic bifurcations as a model.
Coupier, Gwennou +6 more
arxiv +8 more sources
The future of intensive care: the study of the microcirculation will help to guide our therapies
Critical Care, 2023 The goal of hemodynamic resuscitation is to optimize the microcirculation of organs to meet their oxygen and metabolic needs. Clinicians are currently blind to what is happening in the microcirculation of organs, which prevents them from achieving an ...
J. Duranteau +8 more
semanticscholar +1 more source
International Journal of Molecular Sciences, 2022 Long COVID (LC) describes the clinical phenotype of symptoms after infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Diagnostic and therapeutic options are limited, as the pathomechanism of LC is elusive.
Charlotte Szewczykowski +21 more
semanticscholar +1 more source
Frontiers in Immunology, 2022 PurposePost hemorrhagic shock mesenteric lymph (PHSML) return contributes to CD4+ T cell dysfunction, which leads to immune dysfunction and uncontrolled inflammatory response.
Hui-Bo Du +27 more
doaj +1 more source
Scientific Reports, 2021 The aim is to investigate that 17β-estradiol (E2)/estrogen receptors (ERs) activation normalizes splenic CD4 + T lymphocytes proliferation and cytokine production through inhibition of endoplasmic reticulum stress (ERS) following hemorrhage.
Peng Wang +14 more
doaj +1 more source
Critical Care Research and Practice, 2012 The microcirculation is the part of the circulation where oxygen, nutrients, hormones, and waste products are exchanged between circulating blood and parenchymal cells.The microcirculation includes not only all the vessels with a diameter
Piagnarelli, Michael +2 more
openaire +5 more sources
Cardiovascular Therapeutics, 2023 Mounting evidence has confirmed that essential hypertension (EH) is closely related to low-grade inflammation, but there is still a lack of in-depth understanding of the state of immune cells in the circulating blood of patients with EH.
Rui Yang +7 more
doaj +1 more source
Coronary microcirculation damage in anthracycline cardiotoxicity
Cardiovascular Research, 2021 Aims The aim of this study was to study changes in coronary microcirculation status during and after several cycles of anthracycline treatment. Methods and results Large-white male pigs (n=40) were included in different experimental protocols (ExPr ...
C. Galán-Arriola +12 more
semanticscholar +1 more source