Results 1 to 10 of about 197,951 (371)

Colloids and the Microcirculation

open access: yesAnesthesia & Analgesia, 2017
Colloid solutions have been advocated for use in treating hypovolemia due to their expected effect on improving intravascular retention compared with crystalloid solutions. Because the ultimate desired effect of fluid resuscitation is the improvement of microcirculatory perfusion and tissue oxygenation, it is of interest to study the effects of ...
Huaiwu He, Dawei Liu, C. Ince
semanticscholar   +6 more sources

The future of intensive care: the study of the microcirculation will help to guide our therapies

open access: yesCritical Care, 2023
The goal of hemodynamic resuscitation is to optimize the microcirculation of organs to meet their oxygen and metabolic needs. Clinicians are currently blind to what is happening in the microcirculation of organs, which prevents them from achieving an ...
J. Duranteau   +8 more
semanticscholar   +1 more source

Long COVID: Association of Functional Autoantibodies against G-Protein-Coupled Receptors with an Impaired Retinal Microcirculation

open access: yesInternational Journal of Molecular Sciences, 2022
Long COVID (LC) describes the clinical phenotype of symptoms after infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Diagnostic and therapeutic options are limited, as the pathomechanism of LC is elusive.
Charlotte Szewczykowski   +21 more
semanticscholar   +1 more source

TLR2/TLR4-Enhanced TIPE2 Expression Is Involved in Post-Hemorrhagic Shock Mesenteric Lymph-Induced Activation of CD4+T Cells

open access: yesFrontiers in Immunology, 2022
PurposePost hemorrhagic shock mesenteric lymph (PHSML) return contributes to CD4+ T cell dysfunction, which leads to immune dysfunction and uncontrolled inflammatory response.
Hui-Bo Du   +27 more
doaj   +1 more source

Estradiol-induced inhibition of endoplasmic reticulum stress normalizes splenic CD4 + T lymphocytes following hemorrhagic shock

open access: yesScientific Reports, 2021
The aim is to investigate that 17β-estradiol (E2)/estrogen receptors (ERs) activation normalizes splenic CD4 + T lymphocytes proliferation and cytokine production through inhibition of endoplasmic reticulum stress (ERS) following hemorrhage.
Peng Wang   +14 more
doaj   +1 more source

Microcirculation [PDF]

open access: yesCritical Care Research and Practice, 2012
The microcirculation is the part of the circulation where oxygen, nutrients, hormones, and waste products are exchanged between circulating blood and parenchymal cells.The microcirculation includes not only all the vessels with a diameter
Piagnarelli, Michael   +2 more
openaire   +5 more sources

Mass Cytometry Reveals the Imbalanced Immune State in the Peripheral Blood of Patients with Essential Hypertension

open access: yesCardiovascular Therapeutics, 2023
Mounting evidence has confirmed that essential hypertension (EH) is closely related to low-grade inflammation, but there is still a lack of in-depth understanding of the state of immune cells in the circulating blood of patients with EH.
Rui Yang   +7 more
doaj   +1 more source

Coronary microcirculation damage in anthracycline cardiotoxicity

open access: yesCardiovascular Research, 2021
Aims The aim of this study was to study changes in coronary microcirculation status during and after several cycles of anthracycline treatment. Methods and results Large-white male pigs (n=40) were included in different experimental protocols (ExPr ...
C. Galán-Arriola   +12 more
semanticscholar   +1 more source

Phenotyping the Microcirculation [PDF]

open access: yesHypertension, 2012
The role of the microcirculation is increasingly being recognized in the pathophysiology of cardiovascular disease.1,2 The microcirculation is a major site of damage in most target organs of cardiovascular disease, such as the heart, brain, and kidney. Both functional and structural alterations in the small arteries, arterioles, and capillaries are the
Struijker-Boudier, Harry A.J.   +3 more
openaire   +4 more sources

Genes ingenuity pathway analysis unveils smoothelin‐like 1 (SMTNL1) as a key regulatory protein involved in sodium pentobarbital‐induced growth inhibition in breast cancer

open access: yesPharmacology Research & Perspectives, 2023
We previously reported that sodium pentobarbital inhibited the growth of the breast cancer associated with the normalization of microcirculatory hemodynamics and oxygenation.
Bingwei Li   +4 more
doaj   +1 more source

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