Results 1 to 10 of about 77,424 (294)

TLR2/TLR4-Enhanced TIPE2 Expression Is Involved in Post-Hemorrhagic Shock Mesenteric Lymph-Induced Activation of CD4+T Cells

Frontiers in Immunology, 2022
PurposePost hemorrhagic shock mesenteric lymph (PHSML) return contributes to CD4+ T cell dysfunction, which leads to immune dysfunction and uncontrolled inflammatory response.
Hui-Bo Du, Hui-Bo Du, Hui-Bo Du, Sun-Ban Jiang, Zhen-Ao Zhao, Zhen-Ao Zhao, Zhen-Ao Zhao, Hong Zhang, Hong Zhang, Hong Zhang, Li-Min Zhang, Li-Min Zhang, Li-Min Zhang, Zhao Wang, Ya-Xiong Guo, Ya-Xiong Guo, Ya-Xiong Guo, Jia-Yi Zhai, Peng Wang, Zi-Gang Zhao, Zi-Gang Zhao, Zi-Gang Zhao, Chun-Yu Niu, Chun-Yu Niu, Chun-Yu Niu, Li-Na Jiang, Li-Na Jiang, Li-Na Jiang   +27 more
doaj   +1 more source

Estradiol-induced inhibition of endoplasmic reticulum stress normalizes splenic CD4 + T lymphocytes following hemorrhagic shock

Scientific Reports, 2021
The aim is to investigate that 17β-estradiol (E2)/estrogen receptors (ERs) activation normalizes splenic CD4 + T lymphocytes proliferation and cytokine production through inhibition of endoplasmic reticulum stress (ERS) following hemorrhage.
Peng Wang, Li-Na Jiang, Chen Wang, Ying Li, Meng Yin, Hui-Bo Du, Hong Zhang, Ze-Hua Fan, Yan-Xu Liu, Meng Zhao, An-Ling Kang, Ding-Ya Feng, Shu-Guang Li, Chun-Yu Niu, Zi-Gang Zhao   +14 more
doaj   +1 more source

Mass Cytometry Reveals the Imbalanced Immune State in the Peripheral Blood of Patients with Essential Hypertension

Cardiovascular Therapeutics, 2023
Mounting evidence has confirmed that essential hypertension (EH) is closely related to low-grade inflammation, but there is still a lack of in-depth understanding of the state of immune cells in the circulating blood of patients with EH.
Rui Yang, Yuhong He, Honggang Zhang, Qiuju Zhang, Bingwei Li, Changming Xiong, Yubao Zou, Bingyang Liu   +7 more
doaj   +1 more source

Genes ingenuity pathway analysis unveils smoothelin‐like 1 (SMTNL1) as a key regulatory protein involved in sodium pentobarbital‐induced growth inhibition in breast cancer

Pharmacology Research & Perspectives, 2023
We previously reported that sodium pentobarbital inhibited the growth of the breast cancer associated with the normalization of microcirculatory hemodynamics and oxygenation.
Bingwei Li, Xiaoyan Zhang, Xueting Liu, Ailing Li, Jianqun Han   +4 more
doaj   +1 more source

Interaction of Estradiol and Endoplasmic Reticulum Stress in the Development of Esophageal Carcinoma

Frontiers in Endocrinology, 2020
Gender differences in esophageal cancer patients indicate that estradiol may have antitumor effects on esophageal cancer. The initiation of endoplasmic reticulum stress (ERS) can induce apoptosis in esophageal cancer cells.
Chen Wang, Peng Wang, Jun-Chao Liu, Jun-Chao Liu, Zhen-Ao Zhao, Rui Guo, Ying Li, Ya-Sen Liu, Shu-Guang Li, Shu-Guang Li, Zi-Gang Zhao   +10 more
doaj   +1 more source

Evaluation of Signal Degradation Due to Birefringence in a Multiple Reference Optical Coherence Tomography System With Polarization-Based Balanced Detection

IEEE Photonics Journal, 2022
Although time-domain optical coherence tomography (TD-OCT) systems are straightforward to realize, the imaging speed, sensitivity, and imaging depth limit their range of applications.
Anand Arangath, Kai Neuhaus, Sergey Alexandrov, Martin Leahy   +3 more
doaj   +1 more source

Simple Characterization Scheme for Optical Coherence Tomography Systems With Application to a Commercial and a Near-Isometric Resolution Fibre-Based System

IEEE Photonics Journal, 2022
Optical Coherence Tomography (OCT) is a rapidly growing imaging modality in biomedical optics. OCT can perform high-resolution, cross-sectional imaging of the microstructure of biological tissues by measuring the coherent spectrum from the backscattered ...
Rajib Dey, Yi Zhou, Kai Neuhaus, Sergey Alexandrov, Andrew Nolan, Ting-Chiao Chang, Martin Leahy   +6 more
doaj   +1 more source

Therapeutic mechanisms of mesenchymal stem cells in acute respiratory distress syndrome reveal potentials for Covid-19 treatment

Journal of Translational Medicine, 2021
The mortality rate of critically ill patients with acute respiratory distress syndrome (ARDS) is 30.9% to 46.1%. The emergence of the coronavirus disease 2019 (Covid-19) has become a global issue with raising dire concerns.
Wendi Wang, Wei Lei, Lina Jiang, Siqi Gao, Shijun Hu, Zi-Gang Zhao, Chun-Yu Niu, Zhen-Ao Zhao   +7 more
doaj   +1 more source

Effect of Resveratrol on Blood Rheological Properties in LPS-Challenged Rats

Frontiers in Physiology, 2018
Objectives: Abnormal rheological properties induce adverse effects during sepsis. This study sought to investigate the hypothesis that resveratrol (Res) improves blood rheological properties in rats following a lipopolysaccharide (LPS) challenge, and ...
Ying Wang, Ying Wang, Hao Cui, Fei Niu, Shuo-Lin Liu, Yao Li, Li-Min Zhang, Hui-Bo Du, Zi-Gang Zhao, Chun-Yu Niu   +9 more
doaj   +1 more source

p53 SUMOylation Mediates AOPP-Induced Endothelial Senescence and Apoptosis Evasion

Frontiers in Cardiovascular Medicine, 2022
The aging of endothelial cells plays a critical role in the development of age-related vascular disease. We established a model of endothelial premature senescence by application of Advanced oxidation protein products (AOPPs) modified bovine serum ...
Yanjia Chen, Yanjia Chen, Zhuanhua Liu, Hongyu Chen, Xingfu Huang, Xiaoxia Huang, Yang Lei, Qing Liang, Jiayi Wei, Qin Zhang, Xiaohua Guo, Qiaobing Huang   +11 more
doaj   +1 more source