Results 21 to 30 of about 197,951 (371)
Diabetes, cardiovascular disease and the microcirculation
Cardiovascular Diabetology, 2018 Cardiovascular disease (CVD) is the leading cause of mortality in people with type 2 diabetes mellitus (T2DM), yet a significant proportion of the disease burden cannot be accounted for by conventional cardiovascular risk factors.
W. Strain, P. Paldánius
semanticscholar +1 more source
p53 SUMOylation Mediates AOPP-Induced Endothelial Senescence and Apoptosis Evasion
Frontiers in Cardiovascular Medicine, 2022 The aging of endothelial cells plays a critical role in the development of age-related vascular disease. We established a model of endothelial premature senescence by application of Advanced oxidation protein products (AOPPs) modified bovine serum ...
Yanjia Chen +11 more
doaj +1 more source
Neutrophils disturb pulmonary microcirculation in sepsis-induced acute lung injury
European Respiratory Journal, 2019 The lung is highly vulnerable during sepsis, yet its functional deterioration accompanied by disturbances in the pulmonary microcirculation is poorly understood.
I. Park +12 more
semanticscholar +1 more source
Effects of NO synthase inhibitors on the synovial microcirculation in the mouse knee joint [PDF]
, 1999 Production of nitric oxide by the inducible NO synthase (iNOS) is known to be enhanced in chronic joint inflammation and osteoarthritis as well as aseptic loosening of joint prostheses.
Krombach, F. +3 more
core +1 more source
Diabetes, 2020 The pancreatic islet is a highly vascularized endocrine micro-organ. The unique architecture of rodent islets, a so-called core-mantle arrangement seen in two-dimensional images, led researchers to seek functional implications for islet hormone secretion.
Michael P. Dybala +6 more
semanticscholar +1 more source
The medullary microcirculation
Kidney International, 1987 Like other regional circulations, the medullary circulation supplies oxygen and other primary substrates to the medulla and removes carbon dioxide and other waste metabolites. It also acts as a countercurrent exchanger and simultaneously removes water reabsorbed from the renal tubule to preserve mass balance.
Channing R. Robertson +5 more
openaire +3 more sources
Analyzing the human liver vascular architecture by combining vascular corrosion casting and micro-CT scanning: a feasibility study [PDF]
, 2014 Although a full understanding of the hepatic circulation is one of the keys to successfully perform liver surgery and to elucidate liver pathology, relatively little is known about the functional organization of the liver vasculature.
Casteleyn, Christophe +6 more
core +1 more source
Microcirculation: Physiology, Pathophysiology, and Clinical Application
Blood Purification, 2019 This paper briefly reviews the physiological components of the microcirculation, focusing on its function in homeostasis and its central function in the realization of oxygen transport to tissue cells. Its pivotal role in the understanding of circulatory
G. Guven, M. Hilty, C. Ince
semanticscholar +1 more source
COVID-19 Sepsis and Microcirculation Dysfunction
Frontiers in Physiology, 2020 The spreading of Coronavirus (SARS-CoV-2) pandemic, known as COVID-19, has caused a great number of fatalities all around the World. Up to date (2020 May 6) in Italy we had more than 28,000 deaths, while there were more than 205.000 infected.
A. Colantuoni +9 more
semanticscholar +1 more source
Diabetic microangiopathy in Type 1 (insulin-dependent) diabetic patients after successful pancreatic and kidney or solitary kidney transplantation [PDF]
, 1991 To evaluate the beneficial effect of pancreatic grafting on peripheral microcirculation and long-term clinical outcome, we compared data of 28 Type 1 (insulin-dependent) diabetic patients either given a pancreatic and kidney graft simultaneously or given
Abendroth, D. +4 more
core +1 more source