Results 11 to 20 of about 23,824 (301)

Graphene/Ge microcrystal photodetectors with enhanced infrared responsivity

APL Photonics, 2022
We report on the electrical and optical properties of microcrystal arrays obtained by depositing Ge on a deeply patterned Si substrate. Finite difference time domain simulations indicate that the faceted morphology and high refractive index of Ge ...
Virginia Falcone, Andrea Ballabio, Andrea Barzaghi, Carlo Zucchetti, Luca Anzi, Federico Bottegoni, Jacopo Frigerio, Roman Sordan, Paolo Biagioni, Giovanni Isella   +9 more
doaj   +2 more sources

MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography

Nature Communications, 2021
MAL and MyD88 are downstream adaptors of Toll-like receptors (TLR) and the MAL TIR domain forms filaments in vitro, which in turn nucleate the assembly of crystalline arrays of the MyD88 TIR domain.
Max T. B. Clabbers, Susannah Holmes, Timothy W. Muusse, Parimala R. Vajjhala, Sara J. Thygesen, Alpeshkumar K. Malde, Dominic J. B. Hunter, Tristan I. Croll, Leonie Flueckiger, Jeffrey D. Nanson, Md. Habibur Rahaman, Andrew Aquila, Mark S. Hunter, Mengning Liang, Chun Hong Yoon, Jingjing Zhao, Nadia A. Zatsepin, Brian Abbey, Emma Sierecki, Yann Gambin, Katryn J. Stacey, Connie Darmanin, Bostjan Kobe, Hongyi Xu, Thomas Ve   +24 more
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Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals [PDF]

bioRxiv, 2019
Innovative new crystallographic methods are facilitating structural studies from ever smaller crystals of biological macromolecules. In particular, serial X-ray crystallography and microcrystal electron diffraction (MicroED) have emerged as useful ...
A. Wolff, I. Young, R. Sierra, A. Brewster, M. Martynowycz, E. Nango, M. Sugahara, T. Nakane, K. Ito, A. Aquila, A. Bhowmick, J. Biel, S. Carbajo, A. Cohen, S. Cortez, Ana González, T. Hino, D. Im, J. Koralek, M. Kubo, T. S. Lazarou, Takashi Nomura, S. Owada, Avi J. Samelson, Rie Tanaka, Tomoyuki Tanaka, Erin M. Thompson, H. van den Bedem, R. A. Woldeyes, F. Yumoto, Wei Zhao, K. Tono, S. Boutet, S. Iwata, T. Gonen, N. Sauter, J. Fraser, M. Thompson   +37 more
semanticscholar   +4 more sources

Protocol for the use of focused ion-beam milling to prepare crystalline lamellae for microcrystal electron diffraction (MicroED)

STAR Protocols, 2021
Summary: We present an in-depth protocol to reproducibly prepare crystalline lamellae from protein crystals for subsequent microcrystal electron diffraction (MicroED) experiments.
Michael W. Martynowycz, Tamir Gonen
doaj   +2 more sources

Chemoembolizing hepatocellular carcinoma with microsphere cored with arsenic trioxide microcrystal

Drug Delivery, 2020
Chemoembolization for hepatocellular carcinoma (HCC) is often suboptimal due to multiple involved signaling and lack of effective drugs. Arsenic trioxide (ATO) is a potent chemotherapeutic agent, which can target multiple signaling and have substantial ...
Degang Kong, Tao Jiang, Jian Liu, Xinyi Jiang, Bei Liu, Cheng Lou, Baobing Zhao, Steven L. Carroll, Gong Feng   +8 more
doaj   +2 more sources

Sample manipulation and data assembly for robust microcrystal synchrotron crystallography

IUCrJ, 2018
With the recent developments in microcrystal handling, synchrotron microdiffraction beamline instrumentation and data analysis, microcrystal crystallography with crystal sizes of less than 10 µm is appealing at synchrotrons. However, challenges remain in
Gongrui Guo, Martin R. Fuchs, Wuxian Shi, John Skinner, Evanna Berman, Craig M. Ogata, Wayne A. Hendrickson, Sean McSweeney, Qun Liu   +8 more
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Fabrication and Characterization of Graphene Microcrystal Prepared from Lignin Refined from Sugarcane Bagasse

Nanomaterials, 2018
Graphene microcrystal (GMC) is a type of glassy carbon fabricated from lignin, in which the microcrystals of graphene are chemically bonded by sp3 carbon atoms, forming a glass-like microcrystal structure.
Pei-Duo Tang, Qi-Shi Du, Da-Peng Li, Jun Dai, Yan-Ming Li, Fang-Li Du, Si-Yu Long, Neng-Zhong Xie, Qing-Yan Wang, Ri-Bo Huang   +9 more
doaj   +2 more sources

Polarized three-photon-pumped laser in a single MOF microcrystal

Nature Communications, 2016
Higher-order multi-photon pumped polarized lasers promise application in future optoelectronic and biomedical applications. Here, the authors demonstrate a polarized three-photon pumped (3PP) microcavity laser in a single host-guest composite MOF crystal
Huajun He, En Ma, Yuanjing Cui, Jiancan Yu, Yu Yang, Tao Song, Chuan-De Wu, Xueyuan Chen, Banglin Chen, Guodong Qian   +9 more
doaj   +2 more sources

Small Molecule Microcrystal Electron Diffraction for the Pharmaceutical Industry–Lessons Learned From Examining Over Fifty Samples

Frontiers in Molecular Biosciences, 2021
The emerging field of microcrystal electron diffraction (MicroED) is of great interest to industrial researchers working in the drug discovery and drug development space.
J. Bruhn, G. Scapin, A. Cheng, B. Mercado, D. Waterman, Thejusvi Ganesh, S. Dallakyan, B. Read, Travis Nieusma, Kyle W. Lucier, Megan L. Mayer, Nicole Chiang, N. Poweleit, P. McGilvray, Timothy S Wilson, Michael Mashore, Camille Hennessy, Sean Thomson, Bo Wang, C. Potter, B. Carragher   +20 more
semanticscholar   +1 more source

Serial macromolecular crystallography at ALBA Synchrotron Light Source. Erratum

Journal of Synchrotron Radiation, 2022
A revised version of Table 2 of Martin-Garcia et al. [J. Synchrotron Rad. (2022). 29, 896–907] is provided.
Jose M. Martin-Garcia, Sabine Botha, Hao Hu, Rebecca Jernigan, Albert Castellví, Stella Lisova, Fernando Gil, Barbara Calisto, Isidro Crespo, Shatabdi Roy-Chowdhury, Alice Grieco, Gihan Ketawala, Uwe Weierstall, John Spence, Petra Fromme, Nadia Zatsepin, Dirk Roeland Boer, Xavi Carpena   +17 more
doaj   +1 more source