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Microcystin Toxicokinetics, Molecular Toxicology, and Pathophysiology in Preclinical Rodent Models and Humans

open access: yesToxins, 2021
Microcystins are ubiquitous toxins produced by photoautotrophic cyanobacteria. Human exposures to microcystins occur through the consumption of contaminated drinking water, fish and shellfish, vegetables, and algal dietary supplements and through ...
Tarana Arman, John D. Clarke
doaj   +2 more sources

Effects of different doses of microcystin-LR exposure on gut development and the microbiota of Xenopus laevis tadpoles [PDF]

open access: yesBMC Microbiology
Background Although the acute toxicity of microcystin-LR has been widely confirmed, its effects on aquatic organisms at environmental concentrations have not been systematically studied.
Jinjin Li   +10 more
doaj   +2 more sources

The Cyanobacterial Hepatotoxin Microcystin Binds to Proteins and Increases the Fitness of Microcystis under Oxidative Stress Conditions [PDF]

open access: yesPLoS ONE, 2011
Microcystins are cyanobacterial toxins that represent a serious threat to drinking water and recreational lakes worldwide. Here, we show that microcystin fulfils an important function within cells of its natural producer Microcystis.
Martin Hagemann   +2 more
exaly   +2 more sources

Potential Linkage Between Zebra Mussel Establishment, Cyanobacterial Community Composition, and Microcystin Levels in United States Lakes [PDF]

open access: yesToxins
Zebra mussel invasion of North American lakes during the last century may play an important role in the occurrence of toxic cyanobacterial blooms. However, empirical evidence quantifying their influence on cyanobacterial community dynamics at broad ...
Feng Zhang   +4 more
doaj   +2 more sources

Persistence of Microcystin in Three Agricultural Ponds in Georgia, USA [PDF]

open access: yesToxins
Cyanobacteria and their toxins can have multiple effects on agricultural productivity and water bodies. Cyanotoxins can be transported to nearby crops and fields during irrigation and may pose a risk to animal health through water sources.
Jaclyn E. Smith   +8 more
doaj   +2 more sources

The use of a benign fast-growing cyanobacterial species to control microcystin synthesis from Microcystis aeruginosa [PDF]

open access: yesFrontiers in Microbiology
IntroductionMicrocystis aeruginosa (M. aeruginosa), one of the most abundant blue-green algae in aquatic environments, produces microcystin by causing harmful algal blooms (HABs).
Hakyung Lee   +9 more
doaj   +2 more sources

Widespread Distribution and Adaptive Degradation of Microcystin Degrader (mlr-Genotype) in Lake Taihu, China

open access: yesToxins, 2021
Microbial degradation is an important route for removing environmental microcystins (MCs). Here, we investigated the ecological distribution of microcystin degraders (mlr-genotype), and the relationship between the substrate specificity of the ...
Chenlin Hu   +4 more
doaj   +1 more source

Impact of temperature on the temporal dynamics of microcystin in Microcystis aeruginosa PCC7806

open access: yesFrontiers in Microbiology, 2023
Cyanobacterial blooms pose a serious threat to water quality and human health due to the production of the potent hepatotoxin microcystin. In microcystin-producing strains of the widespread genus Microcystis, the toxin is largely constitutively produced,
Souvik Roy   +2 more
doaj   +1 more source

Microcystin as a biogeochemical cycle: Pools, fluxes, and fates of the cyanotoxin in inland waters

open access: yesLimnology and Oceanography Letters, 2023
Microcystin poses a serious threat to aquatic ecosystems and human health. There is a pressing need to understand the production, movement, and storage of microcystin in lakes.
Quin K. Shingai, Grace M. Wilkinson
doaj   +1 more source

Variability in microcystin quotas during a Microcystis bloom in a eutrophic lake.

open access: yesPLoS ONE, 2021
Microcystis is a bloom-forming genus of cyanobacteria with some genotypes that produce highly toxic microcystin hepatotoxins. In waterbodies where biological and physical factors are relatively homogenous, toxin quotas (the average amount of toxin per ...
Susanna A Wood   +5 more
doaj   +1 more source

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