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A Review of Nephrotoxicity of Microcystins [PDF]
Cyanobacterial blooms triggered by eutrophication and climate change have become a global public health issue. The toxic metabolites microcystins (MCs) generated by cyanobacteria can accumulate in food chain and contaminate water, thus posing a potential threat to human and animals health.
Shuaishuai Xu +6 more
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Chirality in microcystins [PDF]
A new method has been developed to identify the isomers of amino acids by derivatization of the corresponding standards with 1-fluoro-2,4-dinitrophenyl-5-L-alanine amide (Marfey's reagent or FDAA) and analysis of the diastereomeric derivatives by a liquid chromatography-thermospray mass spectrometry technique.
openaire +2 more sources
Effects of lake warming on the seasonal risk of toxic cyanobacteria exposure
Incidence of elevated harmful algal blooms and concentrations of microcystin are increasing globally as a result of human‐mediated changes in land use and climate.
Nicole M. Hayes +3 more
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Bacterioplankton plays an essential role in aquatic ecosystems, and cyanobacteria are an influential part of the microbiome in many water bodies. In freshwaters used for recreational activities or drinking water, toxic cyanobacteria cause concerns due to
Pia I. Scherer +6 more
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Overexpression of Nrf2 protects against microcystin-induced hepatotoxicity in mice. [PDF]
Oxidative stress and glutathione (GSH) depletion are implicated in mycocystin hepatotoxicity. To investigate the role of nuclear factor erythroid 2-related factor 2 (Nrf2) in microcystin-induced liver injury, Nrf2-null, wild-type, and Keap1-hepatocyte ...
Yuan-Fu Lu +5 more
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Dog Poisonings Associated with a Microcystis aeruginosa Bloom in the Netherlands
In early autumn 2011, three dogs died after they had been exposed to a Microcystis aeruginosa bloom on Lake Amstelmeer, The Netherlands. The cyanobacterial scum from the lake contained up to 5.27 × 103 μg g−1 dry-weight microcystin, the vomit of one of ...
Miquel Lürling, Elisabeth J. Faassen
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Metagenomic identification of bacterioplankton taxa and pathways involved in microcystin degradation in lake erie. [PDF]
Cyanobacterial harmful blooms (CyanoHABs) that produce microcystins are appearing in an increasing number of freshwater ecosystems worldwide, damaging quality of water for use by human and aquatic life.
Xiaozhen Mou +4 more
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The ubiquitous freshwater cyanobacterium Microcystis is remarkably successful, showing a high tolerance against fluctuations in environmental conditions.
Arthur Guljamow +5 more
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Microcystins produced during harmful cyanobacterial blooms are a public health concern. Although patterns are emerging, the environmental cues that stimulate production of microcystin remain confusing, hindering our ability to predict fluctuations in ...
Robbie M. Martin +9 more
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Microcystin-LR does not induce alterations to transcriptomic or metabolomic profiles of a model heterotrophic bacterium. [PDF]
Microcystins are secondary metabolites produced by several freshwater, bloom-forming cyanobacterial species. Microcystin-producing cyanobacteria co-occur with a complex community of heterotrophic bacteria.
Robbie M Martin +6 more
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