Results 181 to 190 of about 11,204 (224)

Microcystin-LR-induced Ultrastructural Changes in Rats

Veterinary Pathology, 1990
The ultrastructure of hepatic, pulmonary, and renal lesions was evaluated in rats injected intraperitoneally with a lethal dose of microcystin-LR (MCLR, 160 μg/kg), a cyclic heptapeptide hepatotoxin produced by the blue-green algae, Microcystis aeruginosa.
S B, Hooser, V R, Beasley, E J, Basgall, W W, Carmichael, W M, Haschek   +4 more
openaire   +2 more sources

FLUORESCENT POLARIZATION IMMUNOASSAY OF MICROCYSTIN-LR

Institute of information technology, 2021
To control the highly toxic phycotoxin microcystin-LR, which comtaminates food, a test sys-tem based on polarizing fluorescent immunoassay has been developed allowing for rapid screening testing, the detection limit of microcystin-LR is up to 7.5 ng / ml; duration of analy-sis – 10 min.
Olga Dmitrievna Hendrickson, Elena Anatolievna Zvereva, Ksenia Alekseevna Maksimova, Alexandra Pavlovna Bondarenko, Sergey Aleksandrovich Eremin   +4 more
openaire   +1 more source

Electrochemical and conformational studies of microcystin–LR

Analytica Chimica Acta, 2000
Abstract The detection of microcystins in freshwater and in biological samples has become increasingly important due to their toxicity and tumor-promoting nature. This paper describes the electrochemical characterization of microcystin–LR using cyclic voltammetry and anodic stripping voltammetry at different substrates of gold, platinum, glassy ...
Ozsoz, M, Yan, F, Sadik, OA
openaire   +1 more source

Effects of microcystin-LR on mouse lungs

Toxicon, 2007
Toxic cyanobacteria blooms in drinking water supplies have been an increasing public health concern all over the world. Human populations can be exposed to microcystins, an important family of cyanotoxins, mainly by oral ingestion. However, inhalation from recreational water and hemodialysis can represent other routes.
Raquel M, Soares, Viviane R, Cagido, Rodrigo B, Ferraro, José Roberto, Meyer-Fernandes, Patrícia R M, Rocco, Walter A, Zin, Sandra M F O, Azevedo   +6 more
openaire   +2 more sources

A Fluorescent Microplate Assay for Microcystin-LR

Analytical Biochemistry, 1999
A fluorescent enzyme inhibition assay for microcystin-LR was developed using a new fluorescent substrate of protein phosphatases 1 (PP1) and 2A (PP2A), 6,8-difluoro-4-methylumbelliferyl phosphate. The PP1 and PP2A inhibition assay for microcystin-LR was performed in a microtiter plate and the fluorescence yielded by the enzymatic hydrolysis of the ...
O I, Fontal, M R, Vieytes, J M, Baptista de Sousa, M C, Louzao, L M, Botana   +4 more
openaire   +2 more sources

Microcystin‐LR in Brazilian Aquaculture Production Systems

Water Environment Research, 2010
The growth of aquaculture production systems, mostly the sport‐fishing kind, coupled with a lack of control, brings about concerns on the quality of water and food produced. The current paper determines which factors may trigger the growth of cyanobacteria, with subsequent concentrations of microcystins in collected water samples, at the surface and in
Barros, Ludmilla S. S., de Souza, Fagner Correia, Tavares, Lucia Helena S., Amaral, Luiz A.   +3 more
openaire   +3 more sources

Ms identification of microcystin-LR chlorination by-products

Chemosphere, 2009
Drinking water disinfection by chlorine is known to reduce concentration of microcystin, but compounds formed are rarely considered. In this work the chlorination of microcystin-LR has been studied by monitoring reactants consumption and reaction products using the linear trap quad-Orbitrap (LTQ-Orbitrap) technology.
Merel, Sylvain, Le Bot, Barbara, Clément, Michel, Seux, René, Thomas, Olivier   +4 more
openaire   +3 more sources

Microcystin LR degradation by Pseudomonas aeruginosa alkaline protease

Chemosphere, 1997
We isolated several species of bacteria from the surface water of a Japanese lake. Of the isolated bacteria, Pseudomonas aeruginosa was the only species which could degrade microcystin LR in vitro. Microcystin LR decreased to 4.5% of the spiked microcystin LR quantity in the P.
S, Takenaka, M F, Watanabe
openaire   +2 more sources

Non-enzymatic portable optical sensors for microcystin-LR

Chemical Communications, 2018
We report a selective non-enzymatic optical sensor for fast and low-cost detection of microcystin-LR and POCT estimation of water toxicity.
Larisa Lvova, Carla Guanais Gonçalves, Luca Prodi, Marco Lombardo, Nelsi Zaccheroni, Emanuela Viaggiu, Roberta Congestri, Licia Guzzella, Fiorenzo Pozzoni, Corrado Di Natale, Roberto Paolesse   +10 more
openaire   +7 more sources

Intratracheal administration of microcystin-LR, and its distribution

Toxicon, 2001
Microcystin-LR (MCLR) was injected into mice intratracheally, absorption from the lungs was easy and it was confirmed that both the cause of death and lethality dose level were the same as by intraperitoneal injection treatment. An immunostaining method revealed that there was a time lag of about 60 min before accumulation of MCLR, and that it caused ...
E, Ito, F, Kondo, K, Harada
openaire   +2 more sources