Results 191 to 200 of about 11,325 (225)
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Experimental studies on removal of microcystin-LR by peat

Journal of Hazardous Materials, 2010
Cyanotoxins have caused worldwide concerns for their eclectic occurrence and toxic effects, which led to an intensive search of cost-effective techniques for their removal from contaminated waters. A range of biomaterials was tested for their efficacy to adsorb a potent cyanotoxin, microcystin-LR (MCLR).
Sathishkumar, M.   +4 more
openaire   +2 more sources

Characterization of Sublethal Microcystin-LR Exposure in Mice

Veterinary Pathology, 2002
Microcystin-LR (MCLR) is a potent hepatotoxin produced by the cyanobacterium Microcystis aeruginosa. The histology of acute lethal toxicity has been well characterized, but histology is limited regarding sublethal exposure. Balb/C mice were given a single sublethal dose of MCLR (45 μg/kg) and euthanized at 2, 4, 12, and 24 hours after exposure ...
R E, Guzman, P F, Solter
openaire   +2 more sources

Intratracheal administration of microcystin-LR, and its distribution

Toxicon, 2001
Microcystin-LR (MCLR) was injected into mice intratracheally, absorption from the lungs was easy and it was confirmed that both the cause of death and lethality dose level were the same as by intraperitoneal injection treatment. An immunostaining method revealed that there was a time lag of about 60 min before accumulation of MCLR, and that it caused ...
E, Ito, F, Kondo, K, Harada
openaire   +2 more sources

Cyclosporin A — a chemoprotectant against microcystin-LR toxicity

Toxicology Letters, 1990
Microcystin-LR (MCLR) is a potent hepatotoxin that rapidly produces death in experimental animals. We have shown that cyclosporin A (CsA) can prevent the toxic and lethal effects of MCLR in mice. The LD50 of MCLR in mice is approximately 61 micrograms/kg, and 100 micrograms/kg produces death in 100% of treated mice.
S J, Hermansky, P J, Casey, S J, Stohs
openaire   +2 more sources

Microcystin‐LR in Brazilian Aquaculture Production Systems

Water Environment Research, 2010
The growth of aquaculture production systems, mostly the sport‐fishing kind, coupled with a lack of control, brings about concerns on the quality of water and food produced. The current paper determines which factors may trigger the growth of cyanobacteria, with subsequent concentrations of microcystins in collected water samples, at the surface and in
Barros, Ludmilla S. S.   +3 more
openaire   +3 more sources

Hepatotoxicity of microcystin-LR in fed and fasted rats

Toxicon, 1991
The LD50 (25 hr, i.p.) for microcystin-LR in fed rats (122 micrograms/kg) was significantly higher than that in fasted rats (72 micrograms/kg). At doses of 100, 150 and 200 micrograms of microcystin-LR per kg, the median times to death were 31.9, 18.2 and 11.2 hr for fed rats, and 1.8, 1.7 and 1.5 hr for fasted rats. A sublethal dose of microcystin (50
G A, Miura   +3 more
openaire   +2 more sources

Brönsted Catalyzed Hydrolysis of Microcystin-LR by Siderite

Environmental Science & Technology, 2018
Six naturally occurring minerals were employed to catalyze the hydrolysis of microcystin-LR (MC-LR) in water. After preliminary screening experiments, siderite stood out among these minerals due to its higher activity and selectivity. In comparison with kaolinite, which is known to act as a Lewis acid catalyst, siderite was found to act primarily as a ...
Yanfen Fang   +6 more
openaire   +2 more sources

Lack of teratogenicity of microcystin‐LR in the mouse and toad

Journal of Applied Toxicology, 2002
AbstractMicrocystin‐LR (MC‐LR) is a cyanobacterial toxin generated by the organism Microcystis aeruginosa. Although the hepatotoxicity of this chemical has been characterized, the potential developmental toxicity in vertebrates has not been well studied.
N, Chernoff   +7 more
openaire   +2 more sources

Visualization of microcystin-LR and sulfides in plateau lakes

Journal of Hazardous Materials
In eutrophic water bodies, sulfides are closely related to the growth of cyanobacteria and the production of microcystin-LR (MC-LR). To date, the underlying interaction mechanism between a sulfides and MC-LR remains controversial. Thus, visually presenting the distribution characteristics of sulfides and MC-LR in contaminated water is crucial. Here, we
Zhaomin, Wang   +6 more
openaire   +2 more sources

Detoxification and degradation of microcystin-LR and -RR by ozonation

Chemosphere, 2010
In the present study, two Microsystins (MCs) of Microcystin-LR and Microcystin-RR were degraded with different dosages of ozone (O(3)). The possible degradation pathways were elucidated by analyzing their intermediates and end-products with liquid chromatography-mass spectrometry (LC-MS) method.
Heng-Feng, Miao   +4 more
openaire   +2 more sources

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