Results 181 to 190 of about 107,595 (212)

The adsorption of microcystin-LR by natural clay particles

Toxicon, 2000
The microcystin cyanobacterial hepatotoxins represent an increasingly severe global health hazard. Since microcystins are found world wide in drinking water reservoirs concern about the impact on human health has prompted investigations into remedial water treatment methods.
R J, Morri, D E, Williams, H A, Luu, C F, Holmes, R J, Andersen, S E, Calvert   +5 more
openaire   +2 more sources

Experimental studies on removal of microcystin-LR by peat

Journal of Hazardous Materials, 2010
Cyanotoxins have caused worldwide concerns for their eclectic occurrence and toxic effects, which led to an intensive search of cost-effective techniques for their removal from contaminated waters. A range of biomaterials was tested for their efficacy to adsorb a potent cyanotoxin, microcystin-LR (MCLR).
Sathishkumar, M., Pavagadhi, S., Vijayaraghavan, K., Balasubramanian, R., Ong, S.L.   +4 more
openaire   +2 more sources

Characterization of Sublethal Microcystin-LR Exposure in Mice

Veterinary Pathology, 2002
Microcystin-LR (MCLR) is a potent hepatotoxin produced by the cyanobacterium Microcystis aeruginosa. The histology of acute lethal toxicity has been well characterized, but histology is limited regarding sublethal exposure. Balb/C mice were given a single sublethal dose of MCLR (45 μg/kg) and euthanized at 2, 4, 12, and 24 hours after exposure ...
R E, Guzman, P F, Solter
openaire   +2 more sources

Intratracheal administration of microcystin-LR, and its distribution

Toxicon, 2001
Microcystin-LR (MCLR) was injected into mice intratracheally, absorption from the lungs was easy and it was confirmed that both the cause of death and lethality dose level were the same as by intraperitoneal injection treatment. An immunostaining method revealed that there was a time lag of about 60 min before accumulation of MCLR, and that it caused ...
E, Ito, F, Kondo, K, Harada
openaire   +2 more sources

Cyclosporin A — a chemoprotectant against microcystin-LR toxicity

Toxicology Letters, 1990
Microcystin-LR (MCLR) is a potent hepatotoxin that rapidly produces death in experimental animals. We have shown that cyclosporin A (CsA) can prevent the toxic and lethal effects of MCLR in mice. The LD50 of MCLR in mice is approximately 61 micrograms/kg, and 100 micrograms/kg produces death in 100% of treated mice.
S J, Hermansky, P J, Casey, S J, Stohs
openaire   +2 more sources

Detoxification and degradation of microcystin-LR and -RR by ozonation

Chemosphere, 2010
In the present study, two Microsystins (MCs) of Microcystin-LR and Microcystin-RR were degraded with different dosages of ozone (O(3)). The possible degradation pathways were elucidated by analyzing their intermediates and end-products with liquid chromatography-mass spectrometry (LC-MS) method.
Heng-Feng, Miao, Fang, Qin, Guan-Jun, Tao, Weny-Yi, Tao, Wen-Quan, Ruan   +4 more
openaire   +2 more sources

Lack of teratogenicity of microcystin‐LR in the mouse and toad

Journal of Applied Toxicology, 2002
AbstractMicrocystin‐LR (MC‐LR) is a cyanobacterial toxin generated by the organism Microcystis aeruginosa. Although the hepatotoxicity of this chemical has been characterized, the potential developmental toxicity in vertebrates has not been well studied.
N, Chernoff, E S, Hunter, L L, Hall, M B, Rosen, C F, Brownie, D, Malarkey, M, Marr, J, Herkovits   +7 more
openaire   +2 more sources

Visualization of microcystin-LR and sulfides in plateau lakes

Journal of Hazardous Materials
In eutrophic water bodies, sulfides are closely related to the growth of cyanobacteria and the production of microcystin-LR (MC-LR). To date, the underlying interaction mechanism between a sulfides and MC-LR remains controversial. Thus, visually presenting the distribution characteristics of sulfides and MC-LR in contaminated water is crucial. Here, we
Zhaomin, Wang, Yu, Hao, Jianping, Shen, Bingyan, Li, Huiyan, Chuan, Ping, Xie, Yong, Liu   +6 more
openaire   +2 more sources

[Study on DNA damage induced by microcystin-LR].

Wei sheng yan jiu = Journal of hygiene research, 2005
To investigate whether microcystin-LR (MC-LR) at doses which were not cytotoxic can induce DNA damage and compare its effect on HL-7702 and KB cell lines.Cytotoxin and DNA damage were detected by MTT and comet assay, respectively.As doses ranged from 10 to 100 micro/L, MC-LR showed no significant impact on viability of these two cell lines.
Wu, He-yan, Su, Jin, Shi, Wei
openaire   +2 more sources

Differences in the chlorine reactivity of four microcystin analogues

Water Research, 2006
Urs von Gunten, Gayle Newcombe, Lionel Ho   +2 more
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