Results 61 to 70 of about 23,887 (275)

Transcriptomic Analysis Reveals the Pathways Associated with Resisting and Degrading Microcystin in Ochromonas.

open access: yesEnvironmental Science and Technology, 2018
Toxic Microcystis bloom is a tough environment problem worldwide. Microcystin is highly toxic and is an easily accumulated secondary metabolite of toxic Microcystis that threatens water safety.
Lu Zhang   +8 more
semanticscholar   +1 more source

Machine Learning Assisted Fluorescent Sensor Array for Sensing Applications

open access: yesAdvanced Sensor Research, Volume 5, Issue 2, February 2026.
Chemical analysis is being revolutionized by the combination of the high‐dimensional, multi‐channel signals generated by fluorescent sensor arrays and the powerful data analysis enabled by machine learning. This review covers state‐of‐the‐art studies that use machine learning techniques for the identification and quantification of fluorescent sensor ...
Haobo Guo   +2 more
wiley   +1 more source

Persistence of Microcystin in Three Agricultural Ponds in Georgia, USA

open access: yesToxins
Cyanobacteria and their toxins can have multiple effects on agricultural productivity and water bodies. Cyanotoxins can be transported to nearby crops and fields during irrigation and may pose a risk to animal health through water sources.
Jaclyn E. Smith   +8 more
doaj   +1 more source

Protective Effect and Mechanism of Rosiglitazone in α‐amanitin‐induced Hepatotoxicity Via Activation of PPAR‐γ/Nrf2 Signaling Pathway

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 2, February 2026.
ABSTRACT α‐amanitin (α‐AMA), the primary lethal toxin of amanita, primarily targets the liver with a high toxicity and a low lethal dose. As the precise mechanism of intoxication is unclear, and specific antidotes are lacking, α‐AMA‐induced liver injury has a high mortality rate.
Fuping Lai   +8 more
wiley   +1 more source

Variations in the Microcystin Content of Different Fish Species Collected from a Eutrophic Lake

open access: yesToxins, 2013
Microcystins produced from cyanobacteria can accumulate in fish tissues. Liquid chromatography coupled with tandem quadrupole mass spectrometry (LC-MS/MS) is an attractive alternative to immunoassays for the determination of low concentrations of ...
Mylynda Shaskus   +5 more
doaj   +1 more source

Microcystin-LR Detection in Freshwater Body by LC-MS/MS: Impediment for Water quality: Case study on Naharkhoran drinking water treatment plant [PDF]

open access: green, 2022
Cobra Halakoo   +4 more
openalex   +1 more source

Effects of the Amino Acid Constituents of Microcystin Variants on Cytotoxicity to Primary Cultured Rat Hepatocytes

open access: yesToxins, 2013
Microcystins, which are cyclic heptapeptides produced by some cyanobacterial species from algal blooms, strongly inhibit serine/threonine protein phosphatase and are known as hepatotoxins.
Kumiko Shimizu   +8 more
doaj   +1 more source

Absence of Cyanotoxins in Llayta, Edible Nostocaceae Colonies from the Andes Highlands

open access: yesToxins, 2020
Edible Llayta are cyanobacterial colonies consumed in the Andes highlands. Llayta and four isolated cyanobacteria strains were tested for cyanotoxins (microcystin, nodularin, cylindrospermopsin, saxitoxin and β-N-methylamino-L-alanine—BMAA) using ...
Alexandra Galetović   +5 more
doaj   +1 more source

Hepatocyte‐Derived Extracellular Vesicles Deliver miR‐328‐3p to Trigger PP2A‐B56δ–Mediated p‐NLRP3S295‐Dependent Metaflammation in Macrophages upon Microcystin‐LR Exposure

open access: yesAdvanced Science, Volume 13, Issue 6, 30 January 2026.
Hepatocyte‐derived extracellular vesicles deliver miR‐328‐3p to trigger PP2A‐B56δ–mediated p‐NLRP3S295‐dependent metaflammation in macrophages upon microcystin‐LR exposure. 2‐DG, 2‐deoxy‐D‐glucose. B56δ, protein phosphatase 2A‐B56δ. ER, endoplasmic reticulum. iHD‐EV, inducible hepatocyte‐derived extracellular vesicles. IP3R, inositol 1,4,5‐triphosphate
Jia‐Shen Wu   +13 more
wiley   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen   +5 more
wiley   +1 more source

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