Results 21 to 30 of about 10,044 (214)

Microcystin Production in the Tripartite Cyanolichen Peltigera leucophlebia

Molecular Plant-Microbe Interactions, 2009
We show that the cyanobacterial symbionts of a tripartite cyanolichen can produce hepatotoxic microcystins in situ. Microcystins were detected with high-performance liquid chromatography mass spectrometry both from cephalodia of the tripartite ...
Ulla Kaasalainen, Jouni Jokela, David P. Fewer, Kaarina Sivonen, Jouko Rikkinen   +4 more
doaj   +1 more source

Release and removal of intracellular and extracellular microcystins (RR, LR) using nano-Fe3O4 particles as a coagulant aid for polyaluminum chloride

Water-Energy Nexus
The outbreak of algal blooms caused by cyanobacteria has led to a significant concern regarding water safety due to the release of microcystins. This study aimed to investigate the release and removal of microcystins (RR, LR) using coagulant polyaluminum
Hanshu Zhang, Ming Cheng, Bo Zhang
doaj   +1 more source

The Importance of Lake Sediments as a Pathway for Microcystin Dynamics in Shallow Eutrophic Lakes

Toxins, 2015
Microcystins are toxins produced by cyanobacteria. They occur in aquatic systems across the world and their occurrence is expected to increase in frequency and magnitude. As microcystins are hazardous to humans and animals, it is essential to understand
Haihong Song, Liah X. Coggins, Elke S. Reichwaldt, Anas Ghadouani   +3 more
doaj   +1 more source

Pyrolytic behaviour of microcystins and microcystin-spiked algal blooms

Journal of Analytical and Applied Pyrolysis, 2005
Peer ...
Cameán Fernández, A. M., Moreno Navarro, I., Verdejo Robles, Trinidad, González-Vila, Francisco Javier, González-Pérez, José Antonio   +4 more
openaire   +2 more sources

Inactivation of the Burkholderia Toxin Malleicyprol by Enzymatic Cyclopropanol Ring Opening

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Burkholderia pseudomallei and Burkholderia mallei are dangerous pathogens that cause severe diseases with high mortality rates. Their virulence relies in part on malleicyprols, potent toxins containing a highly reactive cyclopropanol group. In this study, we identify BurK, a heme‐dependent oxidoreductase that neutralizes malleicyprols by enzymatically ...
Jonas Fiedler, Ingrid Richter, Katharina Dornblut, Alicia Scharf, Christian Hertweck   +4 more
wiley   +2 more sources

Structural Characterization of New Microcystins Containing Tryptophan and Oxidized Tryptophan Residues

Marine Drugs, 2013
Microcystins are cyclic peptides produced by cyanobacteria, which can be harmful to humans and animals when ingested. Eight of the (more than) 90 microcystin variants presently characterized, contain the amino acid tryptophan.
David P. Hamilton, Stephen Craig Cary, Frode Rise, Christopher O. Miles, Jonathan Puddick, Susanna A. Wood, Michèle R. Prinsep, Alistair L. Wilkins   +7 more
doaj   +1 more source

Cyanobacterial Abundance and Microcystin Profiles in Two Southern British Lakes: The Importance of Abiotic and Biotic Interactions

Toxins, 2020
Freshwater cyanobacteria blooms represent a risk to ecological and human health through induction of anoxia and release of potent toxins; both conditions require water management to mitigate risks.
David M. Hartnell, Ian J. Chapman, Nick G. H. Taylor, Genoveva F. Esteban, Andrew D. Turner, Daniel J. Franklin   +5 more
doaj   +1 more source

Cyanobacterial Toxic and Bioactive Peptides in Freshwater Bodies of Greece: Concentrations, Occurrence Patterns, and Implications for Human Health

Marine Drugs, 2015
Cyanobacterial harmful algal blooms represent one of the most conspicuous waterborne microbial hazards in aquatic environments mostly due to the production of toxic secondary metabolites, mainly microcystins (MCs). Other bioactive peptides are frequently
Spyros Gkelis, Thomas Lanaras, Kaarina Sivonen   +2 more
doaj   +1 more source

Metagenomic identification of bacterioplankton taxa and pathways involved in microcystin degradation in lake erie. [PDF]

PLoS ONE, 2013
Cyanobacterial harmful blooms (CyanoHABs) that produce microcystins are appearing in an increasing number of freshwater ecosystems worldwide, damaging quality of water for use by human and aquatic life.
Xiaozhen Mou, Xinxin Lu, Jisha Jacob, Shulei Sun, Robert Heath   +4 more
doaj   +1 more source

Microcystin‐LR Triggers Renal Tubular Ferroptosis Through Epigenetic Repression of GPX4: Implications for Environmental Nephrotoxicity

Advanced Science, EarlyView.
MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang, Qi Gao, Yi Peng, Huan Zhang, Qi Shen, Meihong Guo, Yuqing Gong, Lei Chu, Weidong Wu, Yanting Wen, Wangsen Cao, Yong Wang, Lihui Wang   +12 more
wiley   +1 more source