Results 41 to 50 of about 18,616 (256)

Structural Characterization of New Microcystins Containing Tryptophan and Oxidized Tryptophan Residues

Marine Drugs, 2013
Microcystins are cyclic peptides produced by cyanobacteria, which can be harmful to humans and animals when ingested. Eight of the (more than) 90 microcystin variants presently characterized, contain the amino acid tryptophan.
David P. Hamilton, Stephen Craig Cary, Frode Rise, Christopher O. Miles, Jonathan Puddick, Susanna A. Wood, Michèle R. Prinsep, Alistair L. Wilkins   +7 more
doaj   +1 more source

Cyanobacterial Abundance and Microcystin Profiles in Two Southern British Lakes: The Importance of Abiotic and Biotic Interactions

Toxins, 2020
Freshwater cyanobacteria blooms represent a risk to ecological and human health through induction of anoxia and release of potent toxins; both conditions require water management to mitigate risks.
David M. Hartnell, Ian J. Chapman, Nick G. H. Taylor, Genoveva F. Esteban, Andrew D. Turner, Daniel J. Franklin   +5 more
doaj   +1 more source

Cyanobacterial Toxic and Bioactive Peptides in Freshwater Bodies of Greece: Concentrations, Occurrence Patterns, and Implications for Human Health

Marine Drugs, 2015
Cyanobacterial harmful algal blooms represent one of the most conspicuous waterborne microbial hazards in aquatic environments mostly due to the production of toxic secondary metabolites, mainly microcystins (MCs). Other bioactive peptides are frequently
Spyros Gkelis, Thomas Lanaras, Kaarina Sivonen   +2 more
doaj   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Effect of dietary cyanobacteria on growth and accumulation of microcystins in Nile tilapia (Oreochromis niloticus)

, 2006
A 12-week growth trial was conducted in a flow-through system to investigate the chronic toxic effect of dietary intake of cyanobacteria on growth, feed utilization and microcystins accumulation in Nile tilapia (Oreochromis niloticus L.) (initial body ...
Yang, Yunxia, Zhu, Xiaoming, Xie, SQ, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Hubei, Peoples R China, Zhao, Min, Gan, Nanqin, Xie, Shouqi, Song, Lirong   +6 more
core   +1 more source

Distributions and Bioaccumulation of Microcystins [PDF]

, 2022
Microcystins are hepatotoxins and tumor promotors, with various deleterious effects on plants as well. There are 270+ known congeners of the toxin microcystin, structural variants of the molecule. These hepatotoxins are produced by cyanobacteria, and are
Glidewell, Dani
core  

The Effect of Cyanobacterial Biomass Enrichment by Centrifugation and GF/C Filtration on Subsequent Microcystin Measurement

Toxins, 2015
Microcystins are cyclic peptides produced by multiple cyanobacterial genera. After accumulation in the liver of animals they inhibit eukaryotic serine/threonine protein phosphatases, causing liver disease or death.
Shelley Rogers, Jonathan Puddick, Susanna A. Wood, Daniel R. Dietrich, David P. Hamilton, Michele R. Prinsep   +5 more
doaj   +1 more source

Metagenomic identification of bacterioplankton taxa and pathways involved in microcystin degradation in lake erie. [PDF]

PLoS ONE, 2013
Cyanobacterial harmful blooms (CyanoHABs) that produce microcystins are appearing in an increasing number of freshwater ecosystems worldwide, damaging quality of water for use by human and aquatic life.
Xiaozhen Mou, Xinxin Lu, Jisha Jacob, Shulei Sun, Robert Heath   +4 more
doaj   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Synergistic and Antagonistic Effects of Chemical Pollutants and Parasitic Fungi on Cyanobacterial Metabolism

Environmental Toxicology, EarlyView.
ABSTRACT Freshwater ecosystems are increasingly impacted by anthropogenic pollutants, including the widely used herbicide metolachlor (MET) and cigarette butt (CB) litter. Parasites represent an additional biotic stressor that can modulate pollutant effects on their hosts.
Erika Berenice Martínez‐Ruiz, Jutta Fastner, Stephanie Spahr, Justyna Wolinska   +3 more
wiley   +1 more source