Results 41 to 50 of about 6,521 (224)

Structural Characterization of New Microcystins Containing Tryptophan and Oxidized Tryptophan Residues

Marine Drugs, 2013
Microcystins are cyclic peptides produced by cyanobacteria, which can be harmful to humans and animals when ingested. Eight of the (more than) 90 microcystin variants presently characterized, contain the amino acid tryptophan.
David P. Hamilton, Stephen Craig Cary, Frode Rise, Christopher O. Miles, Jonathan Puddick, Susanna A. Wood, Michèle R. Prinsep, Alistair L. Wilkins   +7 more
doaj   +1 more source

Phytotoxicity associated to microcystins: a review [PDF]

Brazilian Journal of Biology, 2014
Microcystins (MC) are the most studied toxins of cyanobacteria since they are widely distributed and account for several cases of human and animal poisoning, being potent inhibitors of the serine/threonine protein phosphatases 1 (PP1) and 2A (PP2A). The phosphatases PP1 and PP2A are also present in plants, which may also suffer adverse effects due to ...
Bittencourt-Oliveira, M. C., Hereman, T. C., Cordeiro-Araujo, M. K., Macedo-Silva, I, Dias, C. T., Sasaki, F. F. C., Moura, A. N.   +6 more
openaire   +7 more sources

Effect of dietary cyanobacteria on growth and accumulation of microcystins in Nile tilapia (Oreochromis niloticus)

, 2006
A 12-week growth trial was conducted in a flow-through system to investigate the chronic toxic effect of dietary intake of cyanobacteria on growth, feed utilization and microcystins accumulation in Nile tilapia (Oreochromis niloticus L.) (initial body ...
Yang, Yunxia, Zhu, Xiaoming, Xie, SQ, Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Hubei, Peoples R China, Zhao, Min, Gan, Nanqin, Xie, Shouqi, Song, Lirong   +6 more
core   +1 more source

Cyanobacterial Toxic and Bioactive Peptides in Freshwater Bodies of Greece: Concentrations, Occurrence Patterns, and Implications for Human Health

Marine Drugs, 2015
Cyanobacterial harmful algal blooms represent one of the most conspicuous waterborne microbial hazards in aquatic environments mostly due to the production of toxic secondary metabolites, mainly microcystins (MCs). Other bioactive peptides are frequently
Spyros Gkelis, Thomas Lanaras, Kaarina Sivonen   +2 more
doaj   +1 more source

Cyanobacterial Abundance and Microcystin Profiles in Two Southern British Lakes: The Importance of Abiotic and Biotic Interactions

Toxins, 2020
Freshwater cyanobacteria blooms represent a risk to ecological and human health through induction of anoxia and release of potent toxins; both conditions require water management to mitigate risks.
David M. Hartnell, Ian J. Chapman, Nick G. H. Taylor, Genoveva F. Esteban, Andrew D. Turner, Daniel J. Franklin   +5 more
doaj   +1 more source

Metagenomic identification of bacterioplankton taxa and pathways involved in microcystin degradation in lake erie. [PDF]

PLoS ONE, 2013
Cyanobacterial harmful blooms (CyanoHABs) that produce microcystins are appearing in an increasing number of freshwater ecosystems worldwide, damaging quality of water for use by human and aquatic life.
Xiaozhen Mou, Xinxin Lu, Jisha Jacob, Shulei Sun, Robert Heath   +4 more
doaj   +1 more source

Nanomaterials' Multigenerational Effects by Single and Joint Exposure in Non‐mammalian Models

Environmental Toxicology, EarlyView.
ABSTRACT Nanotoxicology has mainly focused on single‐generation studies, leaving multigenerational toxicity underexplored. Having animal welfare recently gained importance, we aimed to provide the state‐of‐the‐art of knowledge about multigenerational effects in non‐mammalian models in the case of nanomaterials (NM) single and joint exposure to other ...
Andy Joel Taipe Huisa, Analía Ale, Azael Francisco Silva Neto, Lorena De Mendonça Lucena, Marcelo Estrella Josende, Milena Ferreira de Lima, Rhayanny Kethylly Pereira Santos, Martín Federico Desimone, Priscila Gubert, José María Monserrat   +9 more
wiley   +1 more source

Distributions and Bioaccumulation of Microcystins [PDF]

, 2022
Microcystins are hepatotoxins and tumor promotors, with various deleterious effects on plants as well. There are 270+ known congeners of the toxin microcystin, structural variants of the molecule. These hepatotoxins are produced by cyanobacteria, and are
Glidewell, Dani
core  

The Effect of Cyanobacterial Biomass Enrichment by Centrifugation and GF/C Filtration on Subsequent Microcystin Measurement

Toxins, 2015
Microcystins are cyclic peptides produced by multiple cyanobacterial genera. After accumulation in the liver of animals they inhibit eukaryotic serine/threonine protein phosphatases, causing liver disease or death.
Shelley Rogers, Jonathan Puddick, Susanna A. Wood, Daniel R. Dietrich, David P. Hamilton, Michele R. Prinsep   +5 more
doaj   +1 more source

Cyanopeptide Mixtures Induce Variable Synergistic and Antagonistic Effects Across Diverse Human Cell Lines

Environmental Toxicology, EarlyView.
ABSTRACT Cyanobacterial harmful algal blooms (cyanoHABs) threaten human, animal, and ecosystem health and safety through production of toxic secondary metabolites. Microcystis, a cosmopolitan bloom‐forming cyanobacterial genus, is well‐known for producing hepatotoxic microcystins (MCs), but it can produce many other bioactive cyanopeptides, such as ...
Lauren N. Hart, Katherine L. Lev, Sierra Hefferan, Sanduni H. Premathilaka, Sharmila I. Thenuwara, Dragan Isailovic, David H. Sherman, Gregory J. Dick   +7 more
wiley   +1 more source