Results 41 to 50 of about 10,044 (214)

Characterization and Mechanism of Linearized-Microcystinase Involved in Bacterial Degradation of Microcystins

Frontiers in Microbiology, 2021
Microcystins (MCs) are extremely hazardous to the ecological environment and public health. How to control and remove MCs is an unsolved problem all over the world.
Jia Wei, Feiyu Huang, Hai Feng, Isaac Yaw Massey, Tezi Clara, Dingxin Long, Yi Cao, Jiayou Luo, Fei Yang, Fei Yang, Fei Yang   +10 more
doaj   +1 more source

Characterization of Aerosols Containing Microcystin [PDF]

Marine Drugs, 2007
Toxic blooms of cyanobacteria are ubiquitous in both freshwater and brackishwater sources throughout the world. One class of cyanobacterial toxins, calledmicrocystins, is cyclic peptides. In addition to ingestion and dermal, inhalation is a likelyroute of human exposure.
Lorraine C. Backer, Barbara Kirkpatrick, C. Mitch Irvin, Zhou Yue, Yung Sung Cheng   +4 more
openaire   +3 more sources

Protective Effect and Mechanism of Rosiglitazone in α‐amanitin‐induced Hepatotoxicity Via Activation of PPAR‐γ/Nrf2 Signaling Pathway

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 2, February 2026.
ABSTRACT α‐amanitin (α‐AMA), the primary lethal toxin of amanita, primarily targets the liver with a high toxicity and a low lethal dose. As the precise mechanism of intoxication is unclear, and specific antidotes are lacking, α‐AMA‐induced liver injury has a high mortality rate.
Fuping Lai, Ya Liao, Jin Wu, Tinggang Wang, Guiyi Zhang, Xiaojun Zhang, Caiyun Xia, Jie Hu, Yuanlan Lu   +8 more
wiley   +1 more source

Satellite Remote Sensing of Drinking Water Intakes in Lake Erie for Cyanobacteria Population Using Two MODIS-Based Indicators as a Potential Tool for Toxin Tracking

Frontiers in Marine Science, 2017
The growth of toxic Cyanobacterium, Microcystis aeruginosa, and the production of toxins, microcystins, pose serious concerns for the ecological health of lakes, such as western Lake Erie.
Feng Zhang, Chenlin Hu, C. K. Shum, Song Liang, Jiyoung Lee, Jiyoung Lee, Jiyoung Lee   +6 more
doaj   +1 more source

Analysis of Total-Forms of Cyanotoxins Microcystins in Biological Matrices: A Methodological Review

Toxins, 2022
Microcystins (MCs) are cyclic heptapeptidic toxins produced by many cyanobacteria. Microcystins can be accumulated in various matrices in two forms: a free cellular fraction and a covalently protein-bound form. To detect and quantify the concentration of
Pierre Bouteiller, Emilie Lance, Thierry Guérin, Ronel Biré   +3 more
doaj   +1 more source

Protective Role of Native Rhizospheric Soil Microbiota Against the Exposure to Microcystins Introduced into Soil-Plant System via Contaminated Irrigation Water and Health Risk Assessment

Toxins, 2021
Microcystins (MCs) produced in eutrophic waters may decrease crop yield, enter food chains and threaten human and animal health. The main objective of this research was to highlight the role of rhizospheric soil microbiota to protect faba bean plants ...
El Mahdi Redouane, Majida Lahrouni, José Carlos Martins, Soukaina El Amrani Zerrifi, Loubna Benidire, Mountassir Douma, Faissal Aziz, Khalid Oufdou, Laila Mandi, Alexandre Campos, Vitor Vasconcelos, Brahim Oudra   +11 more
doaj   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

Advanced Science, Volume 13, Issue 2, 9 January 2026.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen, Ahlem Meziadi, Cyrill Brunner, Maureen McKeague, Lidija Malic, Maryam Tabrizian   +5 more
wiley   +1 more source

SNRK3.15 Is a Crucial Component of the Sulfur Deprivation Response in Arabidopsis thaliana

Plant Direct, Volume 10, Issue 1, January 2026.
ABSTRACT Sulfate deprivation (–S) results in numerous metabolic and phenotypic alterations in plants. Kinases are often key players in transducing nutrient status signals to molecular components involved in metabolic and developmental program regulation, but despite the physiological importance of sulfur, to date, no signaling kinases have been ...
Anastasia Apodiakou, Elmien Heyneke, Saleh Alseekh, Pinnapat Pinsorn, Sabine Metzger, Stanislav Kopriva, Waltraud Schulze, Rainer Hoefgen, Sarah J. Whitcomb   +8 more
wiley   +1 more source

Phospho‐Proteomics Identifies D‐Group MAP Kinases as Substrates of the Arabidopsis Tyrosine Phosphatase RLPH2

Plant Direct, Volume 10, Issue 1, January 2026.
ABSTRACT Despite being one of the few bona fide plant tyrosine phosphatases, the Arabidopsis thaliana Rhizobiales‐like phosphatase 2 (RLPH2) has no known substrates. Utilizing phospho‐proteomics, we identified the activation loop phospho‐tyrosine of several A. thaliana D‐group mitogen‐activated protein kinases (MPKs) as potential RLPH2 substrates.
Anne‐Marie Labandera, Ryan Toth, Sierra Mitchell, Jayde J. Johnson, Brooklyn Kurucz, Juliette Puyaubert, Emmanuel Baudouin, R. Glen Uhrig, Greg B. Moorhead   +8 more
wiley   +1 more source

Newly isolated strains of potentially microcystin-producing cyanobacteria in potable water: case study of Mawoni village, South Africa

Frontiers in Environmental Science
Toxic cyanobacterial species occur in aquatic ecosystems when favourable environmental conditions prevail. These bacteria can produce natural hepatotoxic metabolites called microcystins that can affect the quality of water. Human exposure to microcystins
Mulalo I. Mutoti, Jabulani R. Gumbo, Adivhaho Khwathisi, Afam I. O. Jideani   +3 more
doaj   +1 more source