Results 101 to 110 of about 58,170 (269)

Ciprofloxacin reduces the stimulation of prostaglandin E2 output by interleukin-1 in human tendon-derived cells [PDF]

, 2003
Fluoroquinolone antibiotics such as ciprofloxacin can induce tendon pathology and have various effects on tendon-derived cells in culture. We are investigating whether ciprofloxacin modifies signalling responses in tendon cells.
Corps, AN, Curry, VA, Dutt, D, Harrall, RL, Hazleman, BL, Riley, GP   +5 more
core   +1 more source

Circadian and Ultradian Rhythms of Free Glucocorticoid Hormone Are Highly Synchronized between the Blood, the Subcutaneous Tissue, and the Brain [PDF]

, 2012
Total glucocorticoid hormone levels in plasma of various species, including humans, follow a circadian rhythm that is made up from an underlying series of hormone pulses. In blood most of the glucocorticoid is bound to corticosteroid-binding globulin and
Droste, Susanne K, Lightman, Stafford L, Linthorst, Astrid C E, Qian, Xiaoxiao, Reul, Johannes M H M   +4 more
core   +2 more sources

Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson's disease model.

, 2019
Parkinson's disease (PD) is characterized by the presence of α-synuclein aggregates known as Lewy bodies and Lewy neurites, whose formation is linked to disease development. The causal relation between α-synuclein aggregates and PD is not well understood.
Anichtchik, O., Ashery, U., Bar-On, D., Calo’, L., Dalley, J., Giese, A., Griesinger, C., Iovino, M., Leonov, A., Ryazanov, S., Spillantini, M., Wegrzynowicz, M., Xia, J.   +12 more
core   +1 more source

Tendinopathy—from basic science to treatment [PDF]

, 2008
Chronic tendon pathology (tendinopathy), although common, is difficult to treat. Tendons possess a highly organized fibrillar matrix, consisting of type I collagen and various 'minor' collagens, proteoglycans and glycoproteins.
A McCormick, AH Drummond, AJ Banes, AN Bamji, AN Corps, AN Corps, AN Corps, AP D'Vaz, B Pasternak, BL Woodley, BM Clancy, CA Speed, D Bjur, EM Badley, G Puddu, G Riley, GAC Murrell, GC Jones, GC Jones, GP Riley, GP Riley, Graham Riley, H Alfredson, H Alfredson, H Alfredson, H Alfredson, H Alfredson, H Langberg, H Langberg, H Langberg, H Nagase, HA Awad, J Archambault, JA Paoloni, JA Paoloni, JA Paoloni, JD Rompe, JE Carpenter, JL Cook, JM Archambault, L Józsa, L Ohberg, LC Almekinders, LJ McCawley, M Aström, M Benjamin, M Gotoh, M Gotoh, M Lavagnino, M Lavagnino, MD Chard, ME Jones, MH Khan, N Mafi, P Burssens, P Kannus, R Salingcarnboriboon, RA Bank, RF Ker, RK Smith, SA Fenwick, SC Fu, SG Rees, SP Arnoczky, T Pufe, T Pufe, T Samiric, TG Gerich, TW Ehlers, UM Wewer   +69 more
core   +1 more source

A Microdialysis in Adjuvant Arthritic Rats for Pharmacokinetics–Pharmacodynamics Modeling Study of Geniposide with Determination of Drug Concentration and Efficacy Levels in Dialysate

Molecules, 2018
Microdialysis, a sampling method for pharmacokinetics–pharmacodynamics (PK–PD) modeling in preclinical and clinical studies, is a convenient in vivo sampling technique.
Ran Deng, Wei Wang, Hong Wu, Yunjing Zhang, Wenyu Wang, Li Dai, Zhengrong Zhang, Jun Fu, Feng Li   +8 more
doaj   +1 more source

Lactate: brain fuel in human traumatic brain injury: a comparison with normal healthy control subjects. [PDF]

, 2015
We evaluated the hypothesis that lactate shuttling helps support the nutritive needs of injured brains. To that end, we utilized dual isotope tracer [6,6-(2)H2]glucose, that is, D2-glucose, and [3-(13)C]lactate techniques involving arm vein tracer ...
Brooks, George A, Glenn, Thomas C, Horning, Michael A, Hovda, David A, Martin, Neil A, McArthur, David L, Vespa, Paul   +6 more
core   +1 more source

Intracerebral Proinflammatory Cytokine Increase in Surgically Evacuated Intracerebral Hemorrhage: A Microdialysis Study [PDF]

, 2021
Lovisa Tobieson, Anna Gard, Karsten Ruscher, Niklas Marklund   +3 more
openalex   +1 more source

A bi-directional electrochemically driven micro liquid dosing system with integrated sensor/actuator electrodes [PDF]

, 2000
In this contribution a micro liquid dosing system is presented, which allows bi-directional manipulation of fluids (i.e. pushing out and pulling in of liquids) by the electrochemical generation and removal of gas bubbles. Bi-directionality is obtained by
Bergveld, Piet, Bohm, Sebastian, Olthuis, Wouter   +2 more
core   +3 more sources

Early assessment of kidney allotransplantat function by microdialysis in perioperative period (Case report)

Трансплантология (Москва), 2016
The clinical example illustrates the use of microdialysis techniques for assessing function of the kidney allotransplantat in the early postoperative period.
M. Sh Khubutia, S. V. Zhuravel, A. A. Romanov, I. I. Goncharova, A. V. Pinchuk   +4 more
doaj  

Age-Dependent Changes in Taurine, Serine, and Methionine Release in the Frontal Cortex of Awake Freely-Moving Rats: A Microdialysis Study

Life
Brain function declines because of aging and several metabolites change their concentration. However, this decrease may be a consequence or a driver of aging.
Cristina Cueto-Ureña, María Jesús Ramírez-Expósito, María Pilar Carrera-González, José Manuel Martínez-Martos   +3 more
doaj   +1 more source