Results 91 to 100 of about 58,170 (269)

Blunted Cystine–Glutamate Antiporter Function in the Nucleus Accumbens Promotes Cocaine-induced Drug Seeking [PDF]

, 2008
Repeated cocaine alters glutamate neurotransmission, in part, by reducing cystine–glutamate exchange via system xc−, which maintains glutamate levels and receptor stimulation in the extrasynaptic compartment.
Abdulhameed, Omer, Baker, David A., Grier, Mark D., Kau, Kristen S., Madayag, Aric, Mantsch, John R.   +5 more
core   +1 more source

Vocal learning promotes patterned inhibitory connectivity. [PDF]

, 2017
Skill learning is instantiated by changes to functional connectivity within premotor circuits, but whether the specificity of learning depends on structured changes to inhibitory circuitry remains unclear.
Brainard, Michael S, Cheung, Chung Yan J, Miller, Mark N   +2 more
core   +2 more sources

A Review of Neurotransmitters Sensing Methods for Neuro-Engineering Research

Applied Sciences, 2019
Neurotransmitters as electrochemical signaling molecules are essential for proper brain function and their dysfunction is involved in several mental disorders.
Shimwe Dominique Niyonambaza, Praveen Kumar, Paul Xing, Jessy Mathault, Paul De Koninck, Elodie Boisselier, Mounir Boukadoum, Amine Miled   +7 more
doaj   +1 more source

Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes

British Journal of Pharmacology, Volume 183, Issue 9, Page 2099-2122, May 2026.
Abstract Background and Purpose Lifestyle is closely related to major depressive disorder (MDD). Given the growing focus on the impact of diet on mental health, this study examined how dietary habits affect the pathophysiology of MDD. Experimental Approach Health check‐up data were analysed. Mice received sucrose under chronic unpredictable mild stress
Takatoshi Sakata, Kazuo Kunisawa, Masaya Hasegawa, Yumiko Seto, Aoi Ogawa, Hitomi Kurahashi, Yasuko Yamamoto, Masao Takemura, Hidetoshi Matunami, Tomoya Sugai, Noriki Kutsumura, Kuniaki Saito, Toshitaka Nabeshima, Akihiro Mouri   +13 more
wiley   +1 more source

Neurocritical care monitoring

Journal of Pediatric Critical Care, 2015
Neurocritical care in children is aimed at the prevention and treatment of secondary brain injury. Advanced neuromonitoring tools have gained popularity over the last decade owing to its ability to gather and integrate information related to ...
Ankit Mehta, Karthi Nallasamy
doaj   +1 more source

Metal Organic Framework‐Modified Carbon Fiber Microelectrodes for Enhanced Neurochemical Detection

ChemElectroChem, Volume 13, Issue 8, 15 April 2026.
In this work, we modified carbon fiber microelectrodes (CFMEs) with the iron‐based metal organic framework MIL‐88B(Fe) and examined their performance using fast scan cyclic voltammetry (FSCV). The modification enhanced the dopamine signal at low concentrations and enabled consistent nanomolar detection, while maintaining clear peak separation in ...
Teflah Alshammari, Daniel Coughlin, Nadrah Aldaeefi, Nadiah Alyamni, Alexander G. Zestos   +4 more
wiley   +1 more source

In-vitro gadolinium retro-microdialysis in agarose gel—a human brain phantom study

Frontiers in Radiology
Rationale and objectivesCerebral microdialysis is a technique that enables monitoring of the neurochemistry of patients with significant acquired brain injury, such as traumatic brain injury (TBI) and subarachnoid haemorrhage (SAH).
Chisomo Zimphango, Marius O. Mada, Marius O. Mada, Stephen J. Sawiak, Stephen J. Sawiak, Susan Giorgi-Coll, T. Adrian Carpenter, Peter J. Hutchinson, Peter J. Hutchinson, Keri L. H. Carpenter, Keri L. H. Carpenter, Matthew G. Stovell, Matthew G. Stovell   +12 more
doaj   +1 more source

Oral Cannabidiol Prevents Allodynia and Neurological Dysfunctions in a Mouse Model of Mild Traumatic Brain Injury

Frontiers in Pharmacology, 2019
Neurological dysfunctions are the most impactful and persistent consequences of traumatic brain injury (TBI). Indeed, previous reports suggest that an association between TBI and chronic pain syndromes, as well anxio-depressive behaviors, tends to be ...
Carmela Belardo, Monica Iannotta, Serena Boccella, Rosamaria Cristina Rubino, Flavia Ricciardi, Rosmara Infantino, Gorizio Pieretti, Luigi Stella, Salvatore Paino, Ida Marabese, Rosa Maisto, Livio Luongo, Sabatino Maione, Francesca Guida   +13 more
doaj   +1 more source

Applicability of free drug hypothesis to drugs with good membrane permeability that are not efflux transporter substrates: A microdialysis study in rats

Pharmacology Research & Perspectives, 2020
In clinical pharmacology, the free drug hypothesis has been widely applied in the interpretation of the relationship between pharmacokinetics and pharmacodynamics (PK/PD).
Chun Chen, Hongyu Zhou, Chi Guan, Huanhuan Zhang, Yingying Li, Xue Jiang, Zheng Dong, Yuanyuan Tao, Juan Du, Shuyao Wang, Teng Zhang, Na Du, Junyang Guo, Yaqiong Wu, Zehai Song, Haofei Luan, Yu Wang, Hongwen Du, Shaofeng Zhang, Chen Li, Hang Chang, Tao Wang   +21 more
doaj   +1 more source

A Role for the Kolliker-Fuse Nucleus in Cholinergic Modulation of Breathing at Night During Wakefulness and NREM Sleep [PDF]

, 2010
For many years, acetylcholine has been known to contribute to the control of breathing and sleep. To probe further the contributions of cholinergic rostral pontine systems in control of breathing, we designed this study to test the hypothesis that ...
Bonis, Joshua M., Forster, Hubert V., Kiner, T., Krause, Katie L., Marshall, B. D., Neumueller, Suzanne E., Pan, Lawrence, Qian, B., Smith, A.   +8 more
core   +1 more source