Results 41 to 50 of about 31,449 (270)
Acta Biochimica et Biophysica Sinica, 2022 Gastric cancer is one of the malignant tumors in the world. PAK4 plays an important role in the occurrence and development of gastric cancer, especially in the process of invasion and metastasis.
Li Xiaodong +4 more
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Perturbing Microtubule Integrity Blocks AMP-Activated Protein Kinase-Induced Meiotic Resumption in Cultured Mouse Oocytes [PDF]
, 2012 The oocyte meiotic spindle is comprised of microtubules (MT) that bind chromatin and regulate both metaphase plate formation and karyokinesis during meiotic maturation; however, little information is known about their role in meiosis reinitiation.
Downs, Stephen, Ya, Ru
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Drak Is Required for Actomyosin Organization During Drosophila Cellularization
G3: Genes, Genomes, Genetics, 2016 The generation of force by actomyosin contraction is critical for a variety of cellular and developmental processes. Nonmuscle myosin II is the motor that drives actomyosin contraction, and its activity is largely regulated by phosphorylation of the ...
Ashish B. Chougule +2 more
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TIG3 tumor suppressor-dependent organelle redistribution and apoptosis in skin cancer cells. [PDF]
PLoS ONE, 2011 TIG3 is a tumor suppressor protein that limits keratinocyte survival during normal differentiation. It is also important in cancer, as TIG3 level is reduced in tumors and in skin cancer cell lines, suggesting that loss of expression may be required for ...
Tiffany M Scharadin +4 more
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The Significant Role of the Microfilament System in Tumors
Frontiers in Oncology, 2021 Actin is the structural protein of microfilaments, and it usually exists in two forms: monomer and polymer. Among them, monomer actin is a spherical molecule composed of a polypeptide chain, also known as spherical actin.
Xin Jiang +6 more
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N-wasp Is Required For Structural Integrity Of The Blood-testis Barrier. [PDF]
, 2014 published_or_final_versio
Cheng, CY +10 more
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Asian Journal of Andrology, 2016 Plastins are a family of actin binding proteins (ABPs) known to cross-link actin microfilaments in mammalian cells, creating actin microfilament bundles necessary to confer cell polarity and cell shape.
Nan Li, Chris KC Wong, C Yan Cheng
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A pharmacological cocktail for arresting actin dynamics in living cells. [PDF]
, 2011 The actin cytoskeleton is regulated by factors that influence polymer assembly, disassembly, and network rearrangement. Drugs that inhibit these events have been used to test the role of actin dynamics in a wide range of cellular processes.
Peng, Grace E +2 more
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Synaptopodin-2: a potential tumor suppressor
Cancer Cell International, 2023 Initially identified as an actin-binding protein containing a PSD95-DLG-ZO1 Domain (PZD domain), Synaptopodin 2 (SYNPO2) has long been considered a structural protein ubiquitously expressed in muscular tissues.
Zequn Zheng, Yongfei Song
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Actin Cytoskeleton and Golgi Involvement in Barley stripe mosaic virus Movement and Cell Wall Localization of Triple Gene Block Proteins. [PDF]
, 2013 Barley stripe mosaic virus (BSMV) induces massive actin filament thickening at the infection front of infected Nicotiana benthamiana leaves. To determine the mechanisms leading to actin remodeling, fluorescent protein fusions of the BSMV triple gene ...
Bae, Hanhong +10 more
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