Results 141 to 150 of about 5,523,474 (277)
Protein Inference and Protein Quantification: Two Sides of the Same Coin [PDF]
arXiv, 2012 Motivation: In mass spectrometry-based shotgun proteomics, protein quantification and protein identification are two major computational problems. To quantify the protein abundance, a list of proteins must be firstly inferred from the sample. Then the relative or absolute protein abundance is estimated with quantification methods, such as spectral ...
arxiv
Experimental Physiology, EarlyView.Abstract Position sense is arguably more important than any of the other proprioceptive senses, because it provides us with information about the position of our body and limbs in relationship to one another and to our surroundings; it has been considered to contribute to our self‐awareness.
Uwe Proske
wiley +1 more source
Monocytic cells become less compressible but more deformable upon activation.
PLoS ONE, 2014 AimsMonocytes play a significant role in the development of atherosclerosis. During the process of inflammation, circulating monocytes become activated in the blood stream.
Agnese Ravetto +4 more
doaj +1 more source
Is the intrinsic disorder of proteins the cause of the scale-free architecture of protein-protein interaction networks? [PDF]
arXiv, 2006 In protein-protein interaction networks certain topological properties appear to be recurrent: networks maps are considered scale-free. It is possible that this topology is reflected in the protein structure. In this paper we investigate the role of protein disorder in the network topology.
arxiv
Dual role for pannexin 1 at synapses: regulating functional and morphological plasticity
The Journal of Physiology, EarlyView.Abstract figure legend Pannexin 1 (PANX1) regulation of dendritic spines. The postnatal decrease in PANX1 expression could release key spine cytoskeleton‐regulating proteins enabling spine stabilization. Does the physiological decrease in neuronal PANX1 levels across brain development underlie dendritic spine maturation?
Adriana Casillas Martinez +3 more
wiley +1 more source
Refining the Protein-Protein Interactome using Gene Expression Data [PDF]
arXiv, 2010 Proteins interact with other proteins within biological pathways, forming connected subgraphs in the protein-protein interactome (PPI). Proteins are often involved in multiple biological pathways which complicates interpretation of interactions between proteins.
arxiv
The Journal of Physiology, EarlyView.Abstract figure legend Schematic representation of proposed relationship between hyperglycaemia, gestational diabetes mellitus (GDM), active BCR‐related (ABR), RhoA and actin organization of feto‐placental arterial endothelial cells (fpEC). Hyperglycaemia upregulates ABR, which in turn increases RhoA activation.
Silvija Tokic +9 more
wiley +1 more source
BMC Plant Biology, 2008 Background The cytoskeletal mechanisms that underlie organelle transport in plants are intimately linked to acto-myosin function. This function is mediated by the attachment of myosin heads to F-actin and the binding of cargo to the tails.
Holweg Carola L, Walter Nadine
doaj +1 more source
Protein token: a dynamic unit in protein interactions [PDF]
arXiv, 2018 In this study, we introduced a new unit, named "protein token", as a dynamic protein structural unit for protein-protein interactions. Unlike the conventional structural units, protein token is not based on the sequential or spatial arrangement of residues, but comprises remote residues involved in cooperative conformational changes during protein ...
arxiv
A role for synapsin tetramerization in synaptic vesicle clustering
The Journal of Physiology, EarlyView.Abstract figure legend Model depicting how synapsin oligomers could serve both as a long‐range linker that interconnects synaptic vesicles to form a reserve pool of vesicles and as a spacer that circumvents short‐range electrostatic repulsion between the vesicles.
Sang‐Ho Song, George J. Augustine
wiley +1 more source