Results 151 to 160 of about 5,523,474 (277)

Downregulation of FHOD1 Inhibits Metastatic Potential in A549 Cells

Cancer Management and Research, 2021
Marta Hałas-Wiśniewska, Magdalena Izdebska, Wioletta Zielińska, Alina Grzanka Department of Histology and Embryology, Nicolaus Copernicus University in Toruń, Faculty of Medicine, Collegium Medicum in Bydgoszcz, Bydgoszcz 85-092, PolandCorrespondence ...
Hałas-Wiśniewska M, Izdebska M, Zielińska W, Grzanka A   +3 more
doaj  

Induction of Antiviral Immune Response through Recognition of the Repeating Subunit Pattern of Viral Capsids Is Toll-Like Receptor 2 Dependent

mBio, 2017
Although viruses and viral capsids induce rapid immune responses, little is known about viral pathogen-associated molecular patterns (PAMPs) that are exhibited on their surface.
Kelly M. Shepardson, Benjamin Schwarz, Kyle Larson, Rachelle V. Morton, John Avera, Kimberly McCoy, Alayna Caffrey, Ann Harmsen, Trevor Douglas, Agnieszka Rynda-Apple   +9 more
doaj   +1 more source

Membrane trafficking of synaptic adhesion molecules

The Journal of Physiology, EarlyView.
Abstract figure legend Synaptic cellular adhesion molecules are surface transmembrane receptors that have been shown to internalize via endocytosis, and possibly also recycle, in a process that has been linked to the function and the turnover of the synaptic contact site.
Cristian A. Bogaciu, Silvio O. Rizzoli
wiley   +1 more source

Persistence of quantal synaptic vesicle recycling in virtual absence of dynamins

The Journal of Physiology, EarlyView.
Abstract figure legend Figure depicts the key finding from this study. While loss of all dynamins severely debilitates synaptic vesicle retrieval following repetitive activity, retrieval and recycling of individual synaptic vesicles following spontaneous fusion or sparse stimulation are minimally affected.
Olusoji A. T. Afuwape, Natali L. Chanaday, Merve Kasap, Lisa M. Monteggia, Ege T. Kavalali   +4 more
wiley   +1 more source

Characterization of Syntenin, a Syndecan-binding PDZ Protein, as a Component of Cell Adhesion Sites and Microfilaments

Molecular Biology of the Cell, 2001
Syntenin is a PDZ protein that binds the cytoplasmic C-terminal FYA motif of the syndecans. Syntenin is widely expressed. In cell fractionation experiments, syntenin partitions between the cytosol and microsomes. Immunofluorescence microscopy localizes endogenous and epitope-tagged syntenin to cell adhesion sites, microfilaments, and the nucleus ...
Gunter Reekmans, Marcela Rosas, Daniela Tomatis, Johan Grootjans, Pascale Zimmermann, Iris Leenaerts, Gisèle Degeest, Guido David, Christien Coomans   +8 more
openaire   +3 more sources

Implications for soluble iron accumulation, oxidative stress, and glial glutamate release in motor neuron death associated with sporadic amyotrophic lateral sclerosis

Neuropathology, Volume 45, Issue 3, Page 177-201, June 2025.
Oxidative stress in sporadic amyotrophic lateral sclerosis (ALS) has been evidenced by accumulation of oxidatively modified products of nucleic acids, lipids, sugars, and proteins in the motor neuron system of brains and spinal cords obtained at autopsy from the patients.
Noriyuki Shibata, Ikuko Kataoka, Yukinori Okamura, Kumiko Murakami, Yoichiro Kato, Tomoko Yamamoto, Kenta Masui   +6 more
wiley   +1 more source

Dynamic changes and transcriptome analyses reveal the microfilament skeleton response to water stress in thalli of Neopyropia yezoensis inhabiting the intertidal zone

Plant Stress
The microfilament (MF) cytoskeleton, present in all eukaryotic cells, is not only essential for fundamental cellular processes but also is important in sensing and transducing external signals in response to various developmental cues and abiotic ...
Jiqiang Yin, Ying Sun, Xinping Miao, Jiaxin Qu, Kunjie Zhang, Xue qing Han, Yichi Li, Jiahui Sun, Fanna Kong   +8 more
doaj  

Global protein function prediction in protein-protein interaction networks [PDF]

Nature Biotech. 21, 697-700 (2003), 2003
The determination of protein functions is one of the most challenging problems of the post-genomic era. The sequencing of entire genomes and the possibility to access gene's co-expression patterns has moved the attention from the study of single proteins or small complexes to that of the entire proteome. In this context, the search for reliable methods
arxiv  

Mouse NR2E3R296Q Mutation Disrupts Photoreceptor Developmental Paradigm and Leads to Early‐Onset Progressive Retinal Degeneration by Suppressing RXRG Signaling

The FASEB Journal, Volume 39, Issue 9, 15 May 2025.
The NR2E3R296Q mutation causes rhodopsin mislocalization, increased blue cones in the dorsal retina, and intermediate rhodopsin–arrestin co‐expressing photoreceptors. NR2E3R296Q mice develop early‐onset retinal degeneration, reduced outer nuclear layer thickness, and disorganized outer segments.
Jiacheng Jin, Shuai Wang, Yinjiu Huang, Shanglun Xie   +3 more
wiley   +1 more source

PROTEIN PHOSPHATASE 2A INFLUENCES CORTICAL MICROTUBULE ORGANIZATION IN RESPONSE TO SALT STRESS [PDF]

, 2017
As sessile organisms, plants must use molecular mechanisms to cope with stressors, such as NaCl stress. Protein Phosphatase 2A (PP2A) is a highly-conserved enzyme that regulates many processes including auxin transport, gravitropic responses, ABA ...
Angelini, Gabriella
core   +1 more source