Results 231 to 240 of about 5,523,474 (277)

Role of Small Heat Shock Proteins in the Remodeling of Actin Microfilaments

Biochemistry (Moscow), 2022
Small heat shock proteins (sHsps) play an important role in the maintenance of proteome stability and, particularly, in stabilization of the cytoskeleton and cell contractile apparatus. Cell exposure to different types of stress is accompanied by the translocation of sHsps onto actin filaments; therefore, it is commonly believed that the sHsps are true
Lydia K, Muranova, Vladislav M, Shatov, Nikolai B, Gusev   +2 more
openaire   +2 more sources

Actin Binding Proteins: Regulation of Cytoskeletal Microfilaments

Physiological Reviews, 2003
The actin cytoskeleton is a complex structure that performs a wide range of cellular functions. In 2001, significant advances were made to our understanding of the structure and function of actin monomers. Many of these are likely to help us understand and distinguish between the structural models of actin microfilaments.
Desiree A. Berry, C.G. dos Remedios, Murat Kekic, Masako Tsubakihara, Neil J. Nosworthy, Irina Dedova, Deepak Chhabra   +6 more
openaire   +3 more sources

[Effects of methamidophos on microtubule and microfilament proteins in sciatic nerve of hens].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2005
OBJECTIVE To investigate the dynamic changes of alpha-tubulin, beta-tubulin and beta-actin in sciatic nerve of hen with organophosphorus ester-induced delayed neuropathy (OPIDN).
Xiu-lan Zhao, K. Xie, Xiao-ying Han, Li-hua Yu, Zhen-ping Zhu, Tianliang Zhang, Cui-li Zhang   +6 more
semanticscholar   +1 more source

Possible involvement of microfilaments in protein kinase C translocation

Biochemical and Biophysical Research Communications, 1989
We investigated the role of microfilaments in stimulus-induced translocation of protein kinase C (PKC) in polymorphonuclear leukocytes (PMNs) from C57BL/6 mice. Cytochalasin B and dihydrocytochalasin B almost completely inhibited PKC translocation induced by either TPA or Ca2+ ionophore after pretreatment of cells for 30 min.
Eiko Ishida, Masahiko Ito, Akihiko Sato, Shiro Shigeta, Yoshiyuki Takami, Fuminori Tanabe   +5 more
openaire   +3 more sources

Disruption of endothelial actin microfilaments by protein kinase C inhibitors

Microvascular Research, 1992
In this study, we report that the isoquinolinesulfonamide inhibitors of protein kinase C (PKC), H-7 [1-(5-isoquinolinesulfonyl)-2-methylpiperazine] and its related derivatives H-8 and HA-1004, in addition to staurosporine cause depletion and reorganization of microfilament bundles of porcine aortic endothelial cells in both low-density and confluent ...
Avrum I. Gotlieb, Julie C.M. Yu
openaire   +3 more sources

Purification of microvilli and an analysis of the protein components of the microfilament core bundle

Experimental Cell Research, 1978
Abstract A fast and convenient method for the purification of microvilli from chicken intestinal brush borders is described. The microvilli appear morphologically very similar to those found on intact brush borders. Removal of the microvillus membrane from the microvilli by Triton X-100 treatment reveals compact bundles of microfilaments with small ...
Klaus Weber, Anthony Bretscher
openaire   +3 more sources

Microfilaments from amoeba proteins

Experimental Cell Research, 1971
Summary Bundles of microfilaments have been obtained from a fraction of homogenised amoebae cells after the addition of EDTA. These bundles are made up of many single microfilaments 30–40 A in diameter. An attempt has been made to obtain the protein subunit of these microfilaments. In the detergent Sarkosyl, a subunit of sedimentation constant 2.0×10−
openaire   +3 more sources

Motor proteins regulate force interactions between microtubules and microfilaments in the axon [PDF]

Nature Cell Biology, 2000
It has long been known that microtubule depletion causes axons to retract in a microfilament-dependent manner, although it was not known whether these effects are the result of motor-generated forces on these cytoskeletal elements. Here we show that inhibition of the motor activity of cytoplasmic dynein causes the axon to retract in the presence of ...
Jessica Hughey, Fridoon J. Ahmad, Peter W. Baas, Torsten Wittmann, Anthony A. Hyman, Marion L. Greaser   +5 more
openaire   +2 more sources

Microfilament bundles, lets protein and growth control in somatic cell hybrids

Journal of Cell Science, 1978
ABSTRACT Hybrid cell lines between normal rat embryo fibroblasts and TA3B mouse tumour cells, or between TA3B and BI hamster sarcoma cells, have been examined for the expression of the cell surface large external-transformation-sensitive (LETS) protein and the organization of microfilament bundles.
C J, Marshall, K C, Humphryes, R E, Pollack   +2 more
openaire   +2 more sources

Localization of microfilaments and a tubulin‐like protein in crustacean (Rhynchocinetes typus) spermatozoon

Molecular Reproduction and Development, 1991
AbstractSperm from the decapod crustacean Rhynchocinetes typus undergo dramatic shape changes as they pass from the vas deferens to seawater and interact with the oocyte envelopes. Using FITC‐phalloidin and antitubulin antibodies, we were able to localize microfilaments and a tubulin‐like protein in R. typus spermatozoon. Microfilaments and the tubulin‐
PEREZ, C, ROCO, M, CASTRO, A, DUPRE, E, SCHATTEN, G, BARROS, C   +5 more
openaire   +4 more sources