Results 21 to 30 of about 49,231 (245)
Genotyping with microfluidic devices [PDF]
ELECTROPHORESIS, 2006 AbstractIn the past few years, electrophoresis microchips have been increasingly utilized to interrogate genetic variations in the human and other genomes. Microfluidic devices can be readily applied to speed up existing genotyping protocols, in particular the ones that require electric field‐mediated separations in conjunction with restriction ...
Eszter, Szántai, András, Guttman
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Silk Fibroin Microfluidic Devices [PDF]
Advanced Materials, 2007 Precisely controlling spatio-temporal environmental parameters has become increasingly important in the field of biotechnology. For this reason, biomedical research has increasingly moved toward the design and implementation of microfabricated systems to efficiently improve technologies such as drug delivery,[1] diagnostics,[2] and tissue engineering ...
Christopher J, Bettinger +5 more
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Micromachines, 2020 Microfluidic principles have been widely applied for more than 30 years to solve biological and micro-electromechanical problems. Despite the numerous advantages, microfluidic devices are difficult to manage as their handling comes with several technical
Francesco Costa +3 more
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Molecular Brain, 2023 The central nervous system is organized into different neural circuits, each with particular functions and properties. Studying neural circuits is essential to understanding brain function and neuronal diseases.
Sukmin Han +4 more
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Nanoscale Research Letters, 2019 How to fabricate scale low-cost microfluidic device for detection of biomarkers owns a great requirement. Herein, it is for the first time reported that a new microfluidic device based on bonding polydimethylsiloxane microfluidic channels onto the ...
Shouhui Chen +8 more
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Spheroid Engineering in Microfluidic Devices
ACS Omega, 2023 Two-dimensional (2D) cell culture techniques are commonly employed to investigate biophysical and biochemical cellular responses. However, these culture methods, having monolayer cells, lack cell-cell and cell-extracellular matrix interactions, mimicking the cell microenvironment and multicellular organization.
Atakan Tevlek +4 more
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Development of Microdroplet Generation Method for Organic Solvents Used in Chemical Synthesis
Molecules, 2020 Recently, chemical operations with microfluidic devices, especially droplet-based operations, have attracted considerable attention because they can provide an isolated small-volume reaction field.
Shohei Hattori +8 more
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Micromixing Within Microfluidic Devices
, 2011 Micromixing is a crucial process within microfluidic systems such as micro total analysis systems (μTAS). A state-of-art review on microstructured mixing devices and their mixing phenomena is given. The review first presents an overview of the characteristics of fluidic behavior at the microscale and their implications in microfluidic mixing processes.
Capretto, Lorenzo +3 more
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Chemical-Free Extraction of Functional Mitochondria Using a Microfluidic Device
Inventions, 2018 This paper proposes the use of a chip-based microfluidic device to extract functional and chemical free mitochondria. A simple microfluidic device was designed and fabricated. An osteosarcoma cybrid cell line was employed to demonstrate the efficiency of
Yu-Han Hsiao +5 more
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Slicing Spheroids in Microfluidic Devices for Morphological and Immunohistochemical Analysis
Micromachines, 2020 Microfluidic devices utilizing spheroids play important roles in in vitro experimental systems to closely simulate morphological and biochemical characteristics of the in vivo tumor microenvironment.
Satoru Kuriu +3 more
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