Results 141 to 150 of about 242,823 (354)

Cryptococcal Glucuronoxylomannan Induces Interleukin (IL)‐8 Production by Human Microglia but Inhibits Neutrophil Migration toward IL‐8 [PDF]

, 1998
Myriam M. Lipovsky, Genya Gekker, Shuxian Hu, Laura Ehrlich, Andy I. M. Hoepelman, Phillip K. Peterson   +5 more
openalex   +1 more source

Emerging Nanotechnology Strategies for Obesity Therapy

Advanced Science, EarlyView.
Three types of nanomaterials used for obesity treatment are highlighted, including inorganic nanomaterials, organic nanomaterials and biomimetic nanomaterials. A detailed and comprehensive introduction to the recent nanotechnology strategies for obesity management is also provided, including drug delivery, photodynamic therapy, hyperthermia, gas ...
Weili Chang, Zhaoxu Meng, Yuezhu Zhao, Yake Qi, Zhou Li, He Lian   +5 more
wiley   +1 more source

Neurotrophic Factors Regulate Cathepsin S in Macrophages and Microglia: A Role in the Degradation of Myelin Basic Protein and Amyloid β Peptide [PDF]

, 1999
John P. Liuzzo, Suzana Petanceska, Lakshmi A. Devi   +2 more
openalex   +1 more source

Glycolytic Enzyme HK2 Phosphorylates nSMase1 to Promote Astrocytic Exosomes Biogenesis Contributing to Acute Ischemic Stroke Injury

Advanced Science, EarlyView.
This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen, YuWei Zhou, LongXiang Sheng, FangYing Mai, YuXuan Ding, ShiRan Hong, JiaXin Wu, JiaKai Pi, GuangMei Yan, YiJun Huang, JingJing Duan, Xuefeng Hua, Wei Yin   +12 more
wiley   +1 more source

The Neuroimmunological Nexus of Multiple Sclerosis: Deciphering the Microglial Transcriptomic Tapestry

Neuroglia
Microglia are poorly understood immune cells of the central nervous system that play a determining role in the progression of multiple sclerosis. With the advent of genomic techniques such as single-cell RNA sequencing and single-nucleus RNA sequencing ...
Akanksha Jha, Hemant Kumar
doaj   +1 more source

MICROGLIA: AN EXPERIMENTAL STUDY IN RABBITS AFTER INTRACEREBRAL INJECTION OF BLOOD

, 1929
E. A. Carmichael
openalex   +1 more source

Microglia-Derived Nerve Growth Factor Causes Cell Death in the Developing Retina [PDF]

, 1998
José M. Frade, Yves‐Alain Barde
openalex   +1 more source

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

Advanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu, Shengyu Jin, Xin Fu, Chong Xie, Yi Chen, Liangtang Chang, Yongheng Fan, Donghua He, Xiaoqi Hong, Xi Shen, Xiaoli Zheng, Qiyue Wang, Dao Shi, Fangyuan Li, Daishun Ling, Yangtai Guan, Neng Gong, Xiaoping Tong   +17 more
wiley   +1 more source

Microglia Express CCR5, CXCR4, and CCR3, but of These, CCR5 Is the Principal Coreceptor for Human Immunodeficiency Virus Type 1 Dementia Isolates [PDF]

, 1999
Andrew Albright, Joseph T.C. Shieh, Takayuki Itoh, Benhur Lee, David Pleasure, Michael J. O’Connor, Robert W. Doms, Francisco González‐Scarano   +7 more
openalex   +1 more source

Complement and microglia mediate early synapse loss in Alzheimer mouse models

Science, 2016
Soyon Hong, Victoria F. Beja-Glasser, Bianca M. Nfonoyim, A. Frouin, Shaoming Li, Saranya Ramakrishnan, Katherine M. Merry, Qiaoqiao Shi, A. Rosenthal, B. Barres, C. Lemere, D. Selkoe, B. Stevens   +12 more
semanticscholar   +1 more source