Results 141 to 150 of about 388,044 (340)

Mitochondrial Transplantation via Magnetically Responsive Artificial Cells Promotes Intracerebral Hemorrhage Recovery by Supporting Microglia Immunological Homeostasis

open access: yesAdvanced Materials, Volume 37, Issue 13, April 2, 2025.
A type of magnetically responsive artificial cells (ACs) has been developed, demonstrating the loading of mitochondria and self‐enclosure processes to ensure the protection of mitochondrial transport via the bloodstream. The treatment with ACs effectively transplanted mitochondria around the lesion, thereby improving neurological recovery by supporting
Mi Zhou   +10 more
wiley   +1 more source

The role of microglia and their CX3CR1 signaling in adult neurogenesis in the olfactory bulb

open access: yeseLife, 2017
Microglia play important roles in perinatal neuro- and synapto-genesis. To test the role of microglia in these processes during adulthood, we examined the effects of microglia depletion, via treatment of mice with the CSF-1 receptor antagonist PLX5622 ...
Ronen Reshef   +6 more
doaj   +1 more source

Exercise reduces activation of microglia isolated from hippocampus and brain of aged mice [PDF]

open access: gold, 2013
Rachel A. Kohman   +3 more
openalex   +1 more source

Sacrificial Biofabrication for Vascularization: Concept, Materials, Technologies, and Applications

open access: yesAdvanced Materials, EarlyView.
Vasculature is indispensable for tissue viability in regenerative medicine. The sacrificial biofabrication enables precise fabrication of vascular channels by using temporary templates that are subsequently removed. This review defines the concept and delves into sacrificial materials, surrounding materials, fabrication technologies, and biomedical ...
Jiezhong Shi   +7 more
wiley   +1 more source

Thermally Drawn Multifunctional All‐Hydrogel Fibers for Anti‐Fibrotic and Multimodal Neural Interfaces

open access: yesAdvanced Materials, EarlyView.
Hydrogels demonstrate material properties that mimic the mechanical and chemical environments of biological tissues. Yet, they face challenges during their integration into 3D interfaces. By identifying a class of thermoplastic hydrogels, a strategy is developed to pattern hydrogels in thermally drawn fibers.
Changhoon Sung   +13 more
wiley   +1 more source

Neuron-microglia interactions in mental health disorders: 'For better, and for worse'

open access: yesFrontiers in Immunology, 2016
Persistent cognitive and behavioral symptoms that characterize many mental health disorders arise from impaired neuroplasticity in several key corticolimbic brain regions.
Eric S Wohleb, Eric S Wohleb
doaj   +1 more source

Identification of a Unique TGF-β Dependent Molecular and Functional Signature in Microglia

open access: yesNature Neuroscience, 2013
Microglia are myeloid cells of the CNS that participate both in normal CNS function and in disease. We investigated the molecular signature of microglia and identified 239 genes and 8 microRNAs that were uniquely or highly expressed in microglia versus ...
O. Butovsky   +17 more
semanticscholar   +1 more source

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