Delayed Transplantation of Neural Stem Cells Improves Initial Graft Survival after Stroke
Delayed transplantation of human iPSC‐derived neural progenitor cells (NPCs) enhances graft survival, proliferation, and axonal sprouting after stroke. Using bioluminescence imaging and histology in a mouse model of stroke, it is shown that NPC delivery at 7 days post‐stroke is more effective than acute transplantation, highlighting the importance of ...
Rebecca Z Weber+6 more
wiley +1 more source
The Role of Microglia in Perioperative Pain and Pain Treatment: Recent Advances in Research
Microglia play a crucial role in monitoring the microenvironment of the central nervous system. Over the past decade, the role of microglia in the field of pain has gradually been unraveled.
Shengnan Shi, Xingrui Gong
doaj +1 more source
Identification of Cellular Compartments Involved in Processing of Cathepsin E in Primary Cultures of Rat Microglia [PDF]
Dewi Fatma Suniarti Sastradipura+8 more
openalex +1 more source
Complement and microglia mediate early synapse loss in Alzheimer mouse models
Soyon Hong+12 more
semanticscholar +1 more source
EFTUD2 Regulates Cortical Morphogenesis via Modulation of Caspase‐3 and Aifm1 Splicing Pathways
EFTUD2, a spliceosomal GTPase linked to MFDM, regulates cortical development through apoptotic control. Conditional Eftud2 knockout in murine neural stem cells induces microcephaly and cortical disorganization, while pathogenic variants drive neuronal loss.
Liping Chen+12 more
wiley +1 more source
Human Immunodeficiency Virus Neurotropism: an Analysis of Viral Replication and Cytopathicity for Divergent Strains in Monocytes and Microglia [PDF]
Anuja Ghorpade+8 more
openalex +1 more source
Multiscale Organization of Neural Networks in a 3D Bioprinted Matrix
A 3D bioprint model of primary neurons has been engineered with a millimeter‐scale functional neural network, and it recapitulates in vivo transcriptomic features under both normal and disease conditions to the greatest extent. The successful integration of mature neurons and 3D bioprinting signifies a major advance in neuroscience modeling ...
Huiyu Yang+16 more
wiley +1 more source
Role of Protein Kinase C in Microglia-induced Neurotoxicity in Mesencephalic Cultures [PDF]
Michael McMillian+2 more
openalex +1 more source