Results 171 to 180 of about 242,823 (354)
Late virus replication events in microglia are required for neurovirulent retrovirus-induced spongiform neurodegeneration: evidence from neural progenitor-derived chimeric mouse brains [PDF]
, 1996 William P. Lynch +4 more
openalex +1 more source
Advanced Science, EarlyView.pMM‐PCL, made up of pretreated macrophage menbrane and polycaprolactone, boasts the adsorption of harmful myelin debris in the microenvironment of spinal cord injury. Abstract After spinal cord injury (SCI), a mass of myelin debris derived from injured myelin sheath will be consistently generated and induce macrophages to be foam cells.
Yuchen Zhou +7 more
wiley +1 more source
Microglia heterogeneity in health and disease
FEBS Open BioMicroglia, the resident immune cells of the central nervous system (CNS), have received significant attention due to their critical roles in maintaining brain homeostasis and mediating cerebral immune responses.
Shilauni Dadwal, Michael T. Heneka
doaj +1 more source
Role of Protein Kinase C in Microglia-induced Neurotoxicity in Mesencephalic Cultures [PDF]
, 1997 Michael McMillian +2 more
openalex +1 more source
A Machine‐Learning Approach Identifies Rejuvenating Interventions in the Human Brain
Advanced Science, EarlyView.Rising life expectancy increases the incidence of age‐related neurodegeneration. Reverting brain aging through effective rejuvenation strategies constitutes a promising strategy to counteract these disorders and restore brain function. This study uses a brain‐specific transcriptional aging clock to screen over 43 000 perturbation profiles, identifying ...
Guillem Santamaria +5 more
wiley +1 more source
Exercise, microglia, and beyond – workout to communicate with microglia
Neural Regeneration Research, 2020 Ryuta Koyama, Megumi Andoh
openaire +3 more sources
Mechanotransduction Activates Microglia and Impairs Phagocytosis in Stiff Amyloid‐β Plaques
Advanced Science, EarlyView.The study constructs an in vitro Aβ plaque‐associated microglia model and uses SECM and SICM to in situ monitor changes in ROS levels, membrane permeability, and phagocytosis of microglia during Aβ clearance. It is found out that Aβ stiffness triggers microglial activation via the PIEZO1 mechanotransduction pathway, causing neuroinflammation and ...
Yulin Liu +8 more
wiley +1 more source
Advanced Science, EarlyView.This study combined microscale 3D‐printing with 2D Ti3C2Tx MXene nanosheets to produce electroconductive microfibrous micro‐meshes. By embedding these MXene‐functionalized micro‐meshes within a growth‐supportive macroporous extracellular matrix (ECM)‐based biomaterial, multifunctional biomimetic MXene‐ECM scaffolds were developed.
Ian Woods +10 more
wiley +1 more source
Stereological analysis of astrocyte and microglia in aging mouse hippocampus
, 1998 Jeffrey M. Long +7 more
openalex +1 more source