Results 181 to 190 of about 334,601 (325)

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

A Self‐Reinforced “Microglia Energy Modulator” for Synergistic Amyloid‐β Clearance in Alzheimer's Disease Model [PDF]

Mengmeng Ma, Jing Wang, Kaiming Guo, Wenbin Zhong, Yu Cheng, Li Lin, Yanli Zhao   +6 more
openalex   +1 more source

Decision letter: Neuronal apoptosis drives remodeling states of microglia and shifts in survival pathway dependence

, 2022

openalex   +1 more source

IL4I1⁺ Macrophages and TDO2⁺ Myofibroblasts Drive AhR‐Mediated Immunosuppression and Ferroptosis Resistance in Solid Predominant Lung Adenocarcinoma

Advanced Science, EarlyView.
Solid predominant lung adenocarcinoma exhibits an immune‐excluded, ferroptosis‐resistant niche enriched with IL4I1⁺ TAMs and TDO2⁺ myCAFs. Spatial and multi‐omics analyses reveal AhR‐driven crosstalk that promotes T cell exhaustion and therapy resistance. Blocking AhR with CH‐223191 restores ferroptosis sensitivity, and its combination with ferroptosis
Zhaoxuan Wang, Weijiao Xu, Lei Zhao, Lin Zhong, Wendan Yu, Shengmin Wang, Lu Sun, Tao Guo, Fengzhou Li, Zhuoshi Li, Lei Fang, Shiqing Wang, Guohui Zhang, Guoqing Xue, Wei Guo, Shilei Zhao, Chundong Gu   +16 more
wiley   +1 more source

Depletion of Microglia Increases Cortical Oligodendrocyte Density During Remyelination. [PDF]

Glia
Loo HK, Gallegos J, Mialki C, Perrin GE, Malloy T, Orthmann-Murphy JL.   +5 more
europepmc   +1 more source

NIR‐Triggered Upconversion‐Perovskite Heterostructures for Non‐Genetic, Implant‐Free Optoelectronic Neuromodulation

Advanced Science, EarlyView.
The Single‐Nanostructured Optoelectronic Vehicle for neuromodulation Activation (SNOVA) establishes a paradigm for non‐genetic, implant‐free neuromodulation. By integrating NIR‐excitable UCNPs with broadband‐absorbing perovskite QDs, SNOVA efficiently converts deeply penetrating light into localized electric fields that modulate neuronal ion dynamics ...
Luyue Jiang, Chenguang Ma, Yiping Zhao, Jiazhi Li, Gen Li, Shuang Jin, Haoyang Su, Ye Tian, Yingkang Yang, Yunfu Luo, Lei Huang, Peijie Chen, Yiming Gao, Yi Wei, Yike Xiang, Lunming Qin, Kaihuan Zhang, Yifei Ye, Pengyi Tang, Liuyang Sun   +19 more
wiley   +1 more source

Spatio-Temporal Diversity of Calcium Activity in Microglia. [PDF]

Glia
Horiuchi H, Cheung DL, Ishida J, Nabekura J.   +3 more
europepmc   +1 more source

Targeted nanocarriers for microglia-selective cytochalasin D delivery to modulate neuroinflammation after acute brain injuries

Sabri E. M. Sahnoun, Rozina Noristani, Paolo Alimonti, Jonas Pes, Lara Gubeljak, Shaista Ilyas, Eren Arik, Alexandru Florea, Eva Miriam Buhl, Bernd Neumaier, Sanjay Mathur, Jörg B. Schulz, Felix M. Mottaghy, Pardes Habib   +13 more
openalex   +1 more source

Involvement of proteinases produced by both neurons and microglia in neuronal lesion and death pathways.

, 1998
Hiroshi Nakanishi, Kenji Yamamoto
openalex   +2 more sources

Phagocytic glioblastoma-associated microglia and macrophages populate invading pseudopalisades [PDF]

, 2019
Elena Saavedra-López, Meritxell Roig-Martínez, George P. Cribaro, Paola V. Casanova, José M. Gallego, Ana Pérez‐Vallés, Carlos Barcia   +6 more
openalex   +1 more source