Results 181 to 190 of about 237,619 (355)

Early functional and structural hippocampal impairment in a bilateral common carotid artery stenosis mouse model

Animal Models and Experimental Medicine, EarlyView.
Our study used behavioral tests, laser speckle flowmetry, long‐term potentiation, histochemical staining, molecular experiments, and voxel‐based morphometry to evaluate the hippocampal impairments. It demonstrates early functional and structural impairments in the hippocampus contributing to learning and memory deficits after 1 month of BCAS ...
Ping Tang, Yi Sun, Chunsheng Yang, Nan Zhang   +3 more
wiley   +1 more source

scRNA-Seq reveals age-dependent microglial evolution as a determinant of immune response following spinal cord injury

Brain Research Bulletin
Spinal cord injury (SCI) is a debilitating condition of the central nervous system (CNS) that leads to severe impairments in sensory and motor functions.
Lufei Shao, Yueliang Chang, Jinfang Liu, Leilei Lin, Long Chang, Jialin Zhang, Zhibin Lan, Honglai Zhang, Xiaolei Chen   +8 more
doaj  

Microglia are required for developmental specification of AgRP innervation in the hypothalamus of offspring exposed to maternal high-fat diet during lactation. [PDF]

Elife
Mendoza-Romero HN, Biddinger JE, Bedenbaugh MN, Simerly R.   +3 more
europepmc   +1 more source

Contribution of Microglia/Macrophages to Expansion of Infarction and Response of Oligodendrocytes After Focal Cerebral Ischemia in Rats [PDF]

, 2000
Takuma Mabuchi, Kazuo Kitagawa, Toshiho Ohtsuki, Keisuke Kuwabara, Yoshiki Yagita, Takehiko Yanagihara, Masatsugu Hori, Masayasu Matsumoto   +7 more
openalex   +1 more source

The NLRP3 inflammasome pathway contributes to chronic inflammation in experimental autoimmune uveitis

Animal Models and Experimental Medicine, EarlyView.
The present study investigates the role of the NLRP3 inflammasome in the chronicity of ocular inflammation in uveitis using the experimental autoimmune uveitis (EAU) model. Whole eyes collected from EAU mice, 12 weeks post induction, were sectioned and subjected to immunohistochemistry. The confocal images from these sections were then assessed for the
Avik Shome, Ilva D. Rupenthal, Rachael L. Niederer, Odunayo O. Mugisho   +3 more
wiley   +1 more source

Increase in HLA-DR Immunoreactive Microglia in Frontal and Temporal Cortex of Chronic Schizophrenics [PDF]

, 2000
Katrina Radewicz, L.J. Garey, Stephen M. Gentleman, Richard Reynolds   +3 more
openalex   +1 more source

Advances in CRISPR‐Cas9 in lineage tracing of model animals

Animal Models and Experimental Medicine, EarlyView.
Cell lineage tracing is a key technology for describing the developmental history of individual progenitor cells and assembling them to form a lineage development tree. However, traditional methods have limitations of poor stability and insufficient resolution.
Jingchao Cao, Zihang Guo, Xueling Xu, Pan Li, Yi Fang, Shoulong Deng   +5 more
wiley   +1 more source

Lipid droplet accumulation in microglia and their potential roles. [PDF]

Lipids Health Dis
Li Y, Zhao Q, Wang Y, Du W, Yang R, Wu J, Li Y.   +6 more
europepmc   +1 more source

Distinct Alterations of Inflammatory Biomarkers in Cluster Headache: A Case Control Study

Annals of Neurology, Volume 98, Issue 1, Page 4-18, July 2025.
Objective Investigate the immune system's role in cluster headache by analyzing cytokines in people with cluster headache and headache‐free controls, and explore if certain cytokines could predict a specific phenotype. Methods We measured 45 cytokines in adult participants from the Danish Cluster Headache Biobank in a prospective case–control setup ...
Nunu Laura Timotheussen Lund, Connar Stanley James Westgate, Marie‐Louise Kulas Søborg, Agneta Henriette Snoer, Rigmor Højland Jensen, Thomas Folkman Hansen, Anja Sofie Petersen   +6 more
wiley   +1 more source

OTUD1 exacerbates sepsis-associated encephalopathy by promoting HK2 mitochondrial release to drive microglia pyroptosis. [PDF]

J Neuroinflammation
Jing G, Gong H, Wang H, Zuo J, Wu D, Liu H, Wang X, Yuan M, Xia Y, Du T, Liu W, Wu X, Song X.   +12 more
europepmc   +1 more source