Results 211 to 220 of about 334,601 (325)

The effects of early-life immune activation on microglia-mediated neuronal remodeling and the associated ontogeny of hippocampal-dependent learning in juvenile rats

, 2021
Brittany F. Osborne, Sarah B. Beamish, Jaclyn M. Schwarz   +2 more
openalex   +2 more sources

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Cerebellar Resistance to Amyloid Plaque Deposition and Elevated Microglial ECM Proteoglycan Uptake in 5xFAD Mice. [PDF]

Cells
Cangalaya C, Düsedau HP, Dunay IR, Dityatev A, Stoyanov S.   +4 more
europepmc   +1 more source

Additional file 1 of Ocular hypertension suppresses homeostatic gene expression in optic nerve head microglia of DBA/2 J mice

, 2020
James R. Tribble, Jeffrey M. Harder, Pete A. Williams, Simon W. M. John   +3 more
openalex   +1 more source

A Blood‐Brain Barrier‐Penetrant Ag(III) Corrole Compound Rescues Alzheimer's Disease Pathology by Targeting Aβ42‐Induced Oxidative Stress

Advanced Science, EarlyView.
The newly designed metallo‐corrole (Mor‐Cor)Ag(III) with a morpholino group exhibited promising therapeutic potential for Alzheimer's disease. It significantly reduces reactive oxygen species (ROS), decreases GFAP expression, increases neurite length, and decreases cell death compared to other similar metallo‐corroles. Abstract Alzheimer's disease (AD)
Arup Tarai, Tuhina Mitra, Tanmoy Pain, Jyotiprakash Mallick, Rwiddhi Chakraborty, Kallam Tejaswi, Swagata Ghatak, Sanjib Kar   +7 more
wiley   +1 more source

Unmasking early microglial remodeling in an Alzheimer's disease mouse model. [PDF]

Front Cell Neurosci
Saminathan P, McArdle S, Corey M, Nadig N, Fang C, Gibbons A, Rayadurgam M, Sharma S.   +7 more
europepmc   +1 more source

Reviewer #2 (Public review): MorphoCellSorter: An Andrews plot-based sorting approach to rank microglia according to their morphological features

Sarah Benkeder, Son-Michel Dinh, Paul Marchal, Priscille De Gea, Muriel Thoby-Brisson, Violaine Hubert, Ines Hristovska, Gabriel Pitollat, Kassandre Combet, Laura Cardoit, Bruno Pillot, Christelle Léon, Marlène Wiart, Serge Marty, Jérôme Honnorat, Olivier Pascual, Jean-Christophe Comte   +16 more
openalex   +1 more source

Brain inflammatory cytokines and microglia morphology changes throughout hibernation phases in Syrian hamster

, 2017
Valeria Cogut, J.J. Bruintjes, Bart J. L. Eggen, Eddy A. van der Zee, Robert H. Henning   +4 more
openalex   +2 more sources

The Microbiota Shapes Central Nervous System Myelination in Early Life

Advanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch, Emily G. Knox, Daniel Soong, Thomaz F. S. Bastiaanssen, Kalevi Trontti, Gabriel S. S. Tofani, Sophia Ivaschuk, Michael K. Collins, Donia Arafa, Jatin Nagpal, Iiris Hovatta, David A. Lyons, Gerard Clarke, John F. Cryan   +13 more
wiley   +1 more source

Microglial activity during postnatal development is required for infantile amnesia in mice. [PDF]

PLoS Biol
Stewart E, Zielke LG, de Boer AR, Boulaire GG, Power SD, Ryan TJ.   +5 more
europepmc   +1 more source