Results 211 to 220 of about 360,900 (402)
Late virus replication events in microglia are required for neurovirulent retrovirus-induced spongiform neurodegeneration: evidence from neural progenitor-derived chimeric mouse brains [PDF]
William P. Lynch+4 more
openalex +1 more source
Bidirectional Interaction Between the Brain and Bone in Traumatic Brain Injury
Traumatic brain injury (TBI) disrupts the blood–brain barrier and activates neuroimmune responses, causing metabolic disturbances and long‐term bone mass loss. Concurrent fractures accelerate healing and enhance osteogenesis but disrupt regulatory mechanisms, leading to altered bone dynamics and exacerbating neuroinflammation, complicating recovery ...
Wei Zhang, Jun Zou, Lingli Zhang
wiley +1 more source
Role of Protein Kinase C in Microglia-induced Neurotoxicity in Mesencephalic Cultures [PDF]
Michael McMillian+2 more
openalex +1 more source
pMM‐PCL, made up of pretreated macrophage menbrane and polycaprolactone, boasts the adsorption of harmful myelin debris in the microenvironment of spinal cord injury. Abstract After spinal cord injury (SCI), a mass of myelin debris derived from injured myelin sheath will be consistently generated and induce macrophages to be foam cells.
Yuchen Zhou+7 more
wiley +1 more source
A Machine‐Learning Approach Identifies Rejuvenating Interventions in the Human Brain
Rising life expectancy increases the incidence of age‐related neurodegeneration. Reverting brain aging through effective rejuvenation strategies constitutes a promising strategy to counteract these disorders and restore brain function. This study uses a brain‐specific transcriptional aging clock to screen over 43 000 perturbation profiles, identifying ...
Guillem Santamaria+5 more
wiley +1 more source
Exercise, microglia, and beyond – workout to communicate with microglia
Ryuta Koyama, Megumi Andoh
openaire +3 more sources
Increase in HLA-DR Immunoreactive Microglia in Frontal and Temporal Cortex of Chronic Schizophrenics [PDF]
Katrina Radewicz+3 more
openalex +1 more source
Mechanotransduction Activates Microglia and Impairs Phagocytosis in Stiff Amyloid‐β Plaques
The study constructs an in vitro Aβ plaque‐associated microglia model and uses SECM and SICM to in situ monitor changes in ROS levels, membrane permeability, and phagocytosis of microglia during Aβ clearance. It is found out that Aβ stiffness triggers microglial activation via the PIEZO1 mechanotransduction pathway, causing neuroinflammation and ...
Yulin Liu+8 more
wiley +1 more source