Results 251 to 260 of about 334,601 (325)

Immunoaffinity‐Mimetic Assembly of Peptide‐Aptamer Conjugates and Stem Cell‐Derived Exosomes into Hierarchical Microgels for Spinal Cord Injury Repair

Advanced Science, EarlyView.
Inspired by antibody‐antigen binding, this study develops an unprecedented immunoaffinity‐mimetic assembly strategy, with Peptide‐AptCD63 conjugates acting as antibody surrogates binding CD63 epitopes on mesenchymal stem cell‐derived exosomes. This creates a hierarchical microstructure intended to synergistically integrate antioxidative and anti ...
Dantong Zheng, Yuxin Bai, Zhibo Liu, Zinan Zhao, Yiming Kong, Yao Xu, Qi Jia, Rongrong Zhu, Yong Hu   +8 more
wiley   +1 more source

After Traumatic Brain Injury, EPHA4 Enhances Endoplasmic Reticulum Stress to Promote M1 Microglial Polarization Through the MAPK Signaling Pathway. [PDF]

Mediators Inflamm
Tan Y, Xia J, Liu M, Deng S, Wu H, Qian C.   +5 more
europepmc   +1 more source

Multimodal Layer‐Crossing Interrogation of Brain Circuits Enabled by Microfluidic Axialtrodes

Advanced Science, EarlyView.
The study introduces a flexible microfluidic axialtrode that integrates optical, electrical, and chemical modalities within a single polymer fiber. By redistributing electrodes and fluidic channels along the fiber axis via angled cleaving, it enables simultaneous optogenetic stimulation, electrophysiological recording, and drug delivery across brain ...
Kunyang Sui, Neela K. Codadu, Daman Rathore, Guanghui Li, Marcello Meneghetti, Anders L. Bøcker, Rune W. Berg, Rob C. Wykes, Christos Markos   +8 more
wiley   +1 more source

Traumatic brain injury and post-injury sleep fragmentation differentially alter the microglial transcriptome. [PDF]

Front Immunol
Taylor MA, Boland R, Houle S, Tapp ZM, Davis AC, Cotter C, Sheridan JF, Godbout J, Kokiko-Cochran ON.   +8 more
europepmc   +1 more source

Effects of rapamycin treatment in Npc1^nmf164 microglia at P21.

Caroline E. Murray (22190338), David S. Betancourt-Trompa (22190341), Michael S. Martinez (22190344), Julia M. Carson (22190347), Lindsay J. Walsh (22190350), Will C. Remillard (22190353), Kayla B. Fordyce (22190356), Rohan Reddy (18217185), Ileana Soto (531878)   +8 more
openalex   +1 more source

From the Gut to the Brain: Microplastic‐Associated Neurovascular Dysfunction and Implications for Stroke Risk

Advanced Science, EarlyView.
Chronic oral exposure to microplastics may disrupt gut microbiota homeostasis and intestinal barrier integrity, potentially engaging the gut–brain axis and systemic inflammatory responses. These alterations may be associated with impaired blood–brain barrier function, cerebral microvascular dysfunction, and enhanced endothelial inflammation, pro ...
Hongxing Wang, Yujiao He, Pei Zou, Xiaoyi Wang, Gang Peng, Xiangying Deng   +5 more
wiley   +1 more source

LRRK2 kinase activity restricts NRF2-dependent mitochondrial protection in microglia. [PDF]

J Immunol
Weindel CG, Coleman AK, Ellzey LM, Kumar S, Chaisson SL, Davis JR, Patrick KL, Watson RO.   +7 more
europepmc   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

Advanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li, Yumei Wang, Xiaoxi Fan, Miao Xu, Jiawen Li, Wenfei Tan, Jianxiang Zhang, Heran Li   +7 more
wiley   +1 more source

Compromised hepatic bilirubin clearance drives depressive symptoms via regulating microglial engulfment of dendritic spines. [PDF]

J Neuroinflammation
Sun S, Li M, Ma J, He K, Wang L, Li C, Liu X, Zhang S, Yin T, Yang M, Yang X, Zhang J, Xu C, Li Z, Wang S, Zhu H.   +15 more
europepmc   +1 more source

Antiinflammatory Effects of Orientin-2″-<i>O</i>-Galactopyranoside on Lipopolysaccharide-Stimulated Microglia

, 2014
Xiang Zhou, Ping Gan, Lili Hao, Tao Li, Jia Jia, Bo Gao, Jiangyun Liu, Long Tai Zheng, Xuechu Zhen   +8 more
openalex   +2 more sources