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Microglia Polarization From M1 to M2 in Neurodegenerative Diseases
Microglia-mediated neuroinflammation is a common feature of neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS).
Yafu Yin
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A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease
Hadas Keren-shaul+2 more
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Overview of General and Discriminating Markers of Differential Microglia Phenotypes
Inflammatory processes and microglia activation accompany most of the pathophysiological diseases in the central nervous system. It is proven that glial pathology precedes and even drives the development of multiple neurodegenerative conditions.
Agnieszka M Jurga, Katarzyna Z Kuter
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Negative feedback control of neuronal activity by microglia
Microglia, the brain’s resident macrophages, help to regulate brain function by removing dying neurons, pruning non-functional synapses, and producing ligands that support neuronal survival 1 .
Aditya Nair, Ana Badimon, Anat Kahan
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Biological Reviews, 2021
ABSTRACTMicroglial cells are the scions of foetal macrophages which invade the neural tube early during embryogenesis. The nervous tissue environment instigates the phenotypic metamorphosis of foetal macrophages into idiosyncratic surveilling microglia, which are generally characterised by a small cell body and highly ramified motile processes that ...
Charlotte Isabelle Delage+6 more
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ABSTRACTMicroglial cells are the scions of foetal macrophages which invade the neural tube early during embryogenesis. The nervous tissue environment instigates the phenotypic metamorphosis of foetal macrophages into idiosyncratic surveilling microglia, which are generally characterised by a small cell body and highly ramified motile processes that ...
Charlotte Isabelle Delage+6 more
openaire +3 more sources
Using an ammoniacal silver nitrate stain, we have demonstrated typical microglial cells in three teratomas. Microglia appeared identical to their counterparts in the mature human brain, both resting and slightly hypertrophic types being present in differentiated nervous tissue, which also comprised astrocytes, neurones and ependyma. The implications of
PESCE, CARLO, Tobia F, Scott T.
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Microglia Function in the Central Nervous System During Health and Neurodegeneration
Microglia are resident cells of the brain that regulate brain development, maintenance of neuronal networks, and injury repair. Microglia serve as brain macrophages but are distinct from other tissue macrophages owing to their unique homeostatic ...
Marco Colonna, Oleg Butovsky, Bing Xie
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Seminars in Cell & Developmental Biology, 2019
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Carola V., Viscomi M. T.
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Carola V., Viscomi M. T.
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