Results 21 to 30 of about 865 (192)

Analysis of Potential Mechanism of Herbal Formula Taohong Siwu Decoction against Vascular Dementia Based on Network Pharmacology and Molecular Docking

BioMed Research International, Volume 2023, Issue 1, 2023., 2023
Vascular dementia (VaD) is the second most prevalent dementia, which is attributable to neurovascular dysfunction. Currently, no approved pharmaceuticals are available. Taohong Siwu decoction (TSD) is a traditional Chinese medicine prescription with powerful antiapoptosis and anti‐inflammatory properties.
Ruixin He, Fengjiao He, Zhenliang Hu, Yifang He, Xinting Zeng, Yao Liu, Liang Tang, Ju Xiang, Jianming Li, Binsheng He, Qin Xiang, Wei Lan   +11 more
wiley   +1 more source

Macro- and microhemodynamic disorders as cardiovascular risk factors in overweight young people

Acta Biomedica Scientifica, 2022
Obesity is associated with a high risk of cardiovascular diseases. Therefore, an urgent task of preventive medicine is to search for markers indicating the early development of cardiovascular pathology in young people in order to develop preventive ...
Zh. V. Dzampaeva, E. A. Takoeva
doaj   +1 more source

Exploring the mechanisms of Gui Zhi Fu Ling Wan on varicocele via network pharmacology and molecular docking

Andrologia, Volume 54, Issue 11, December 2022., 2022
Abstract Varicocele (VC) is a common urogenital disease that leads to a high risk of testicular pain or male infertility. The purpose of this research was to explore the molecular mechanism of the Gui Zhi Fu Ling Wan (GFW) in the treatment of VC. The main active ingredients and targets information of GFW were screened by Traditional Chinese Medicine ...
Ruipeng Wang, Xiaoye Qiao, Xiaobin Wang
wiley   +1 more source

Microhemodynamic parameters quantification from intravital microscopy videos [PDF]

Physiological Measurement, 2014
Blood flow and blood-endothelium interactions correspond with the genesis of cardiovascular diseases. Therefore, quantitative analysis of blood flow dynamics at the microcirculation level is of special interest. Regulatory mechanisms mediated by blow flow have been studied in detail using in vitro approaches.
Daniel, Ortiz, Juan Carlos, Briceño, Pedro, Cabrales   +2 more
openaire   +2 more sources

Lymphatic microcirculation profile in the progression of hypertension in spontaneously hypertensive rats

Microcirculation, Volume 29, Issue 6-7, October 2022., 2022
Abstract Objective The contractile behavior of collecting lymphatic vessels occurs in essential hypertension in response to homeostasis, suggesting a possible role for microcirculation. We aimed to clarify the nature of the lymphatic microcirculation profile in spontaneously hypertensive rats (SHRs) and normotensive controls.
Bing Wang, Youming Sheng, Yuan Li, Bingwei Li, Jian Zhang, Ailing Li, Mingming Liu, Honggang Zhang, Ruijuan Xiu   +8 more
wiley   +1 more source

A postresection perfusion deficit in the right colon is an independent predictor of perioperative outcome after major hepatectomy

Journal of Hepato-Biliary-Pancreatic Sciences, Volume 29, Issue 7, Page 785-797, July 2022., 2022
The impact of hepatectomy on splanchnic perfusion has been poorly documented. In this study Birgin and colleagues revealed that major hepatectomy induces a significant reduction in splanchnic perfusion. A postresection microcirculatory perfusion deficit in the right colon was identified as a strong and independent predictor of a complicated ...
Emrullah Birgin, Cui Yang, Anna Brunner, Svetlana Hetjens, Mohammad Rahbari, Ulrich Bork, Christoph Reissfelder, Jürgen Weitz, Nuh N. Rahbari   +8 more
wiley   +1 more source

Microhemodynamic aberrations created by transfusion of stored blood [PDF]

Transfusion, 2013
BackgroundHuman red blood cells (RBCs) can be stored for up to 42 days under controlled conditions. Physical and chemical changes occur during RBC storage, altering their function. This study links stored cell mechanical changes with hemodynamic functional alterations upon transfusion.Study Design and MethodsMechanical properties of fresh and stored ...
Ozlem, Yalcin, Daniel, Ortiz, Amy G, Tsai, Paul C, Johnson, Pedro, Cabrales   +4 more
openaire   +2 more sources

Stem cell‐mediated angiogenesis in skin tissue engineering and wound healing

Wound Repair and Regeneration, Volume 30, Issue 4, Page 421-435, July/August 2022., 2022
Abstract The timely management of skin wounds has been an unmet clinical need for centuries. While there have been several attempts to accelerate wound healing and reduce the cost of hospitalisation and the healthcare burden, there remains a lack of efficient and effective wound healing approaches.
Zoleikha Azari, Simin Nazarnezhad, Thomas J. Webster, Seyed Javad Hoseini, Peiman Brouki Milan, Francesco Baino, Saeid Kargozar   +6 more
wiley   +1 more source

Impact of various wound dressings on wound bed neoangiogenesis in patients with different forms of diabetic foot syndrome [PDF]

Терапевтический архив, 2017
Aim. To investigate the impact of various wound dressings on wound bed neoangiogenesis in patients with different forms of diabetic foot syndrome (DFS). Subjects and methods.
E L Zaitseva, A Yu Tokmakova, L P Doronina, I A Voronkova, G R Galstyan, M V Shestakova   +5 more
doaj   +1 more source

Targeting sphingosine kinase‐1 with the low MW inhibitor SKI‐5C suppresses the development of endometriotic lesions in mice

British Journal of Pharmacology, Volume 178, Issue 20, Page 4104-4118, October 2021., 2021
Background and Purpose Limited evidence suggests that the sphingosine‐1‐phosphate/sphingosine kinase 1 (S1P/SPHK1) signalling pathway is involved in the pathogenesis of endometriosis. Therefore, we analyzed in this study whether the inhibition of SPHK1 and, consequently, decreased levels of S1P affected the vascularization and growth of endometriotic ...
Jeannette Rudzitis‐Auth, Anika Christoffel, Michael D. Menger, Matthias W. Laschke   +3 more
wiley   +1 more source