Resuscitation from Hemorrhagic Shock with a Novel Protein Cocktail Restores Microvascular Perfusion and Protects Vital Organs. [PDF]
IntroductionLow titer O positive Whole Blood (LTOWB) has been introduced in prehospital care to resuscitate patients; however, the logistical obstacles, cost of carrying LTOWB, and the availability of it in trauma situations are a point of concern ...
Munoz CJ +9 more
europepmc +3 more sources
Low-volume resuscitation with normal saline is associated with microvascular endothelial dysfunction after hemorrhage in rats, compared to colloids and balanced crystalloids [PDF]
Background Restoration of endothelial glycocalyx (EG) barrier may be an essential therapeutic target for successful resuscitation. The aim of this study was to compare in vivo the effects of resuscitation with normal saline (NS) to lactated Ringer’s ...
Luciana N. Torres +4 more
doaj +2 more sources
Integrated pancreatic microcirculatory profiles of streptozotocin-induced and insulin-administrated type 1 diabetes mellitus. [PDF]
Abstract Objective As an integrated system, pancreatic microcirculatory disturbance plays a vital role in the pathogenesis of type 1 diabetes mellitus (T1DM), which involves changes in microcirculatory oxygen and microhemodynamics. Therefore, we aimed to release type 1 diabetic and insulin‐administrated microcirculatory profiles of the pancreas ...
Li Y +8 more
europepmc +2 more sources
Evaluation of Renal Microhemodynamics Heterogeneity in Different Strains and Sexes of Mice
Addressing the existing gaps in our understanding of sex- and strain-dependent disparities in renal microhemodynamics, this study conducted an investigation into the variations in renal function and related biological oscillators. Using the genetically diverse mouse models BALB/c, C57BL/6, and Kunming, which serve as established proxies for the study ...
Mingming Liu
exaly +3 more sources
Assessment of spatiotemporal heterogeneity of two-dimensional images on the example of photoplethysmograpic imaging of hemodynamics [PDF]
Background and Objectives: The problem of representation of multidimensional data on a two-dimensional plane arises during the processing of a series of two-dimensional images in the spatiotemporal and time-frequency domains.
Sagaidachnyi, Andrey Aleksandrovich +7 more
doaj +1 more source
Non-invasive point-of-care optical technique for continuous in vivo assessment of microcirculatory function: Application to a preclinical model of early sepsis. [PDF]
This study, entitled “Non‐invasive point‐of‐care optical technique for continuous in vivo assessment of microcirculatory function: Application to a preclincal model of early sepsis,” demonstrated that optical spectroscopy is a reliable and non‐invasive point‐of‐care tool for in vivo detection of exaggerated vasomotion at the onset of sepsis.
Eskandari R +6 more
europepmc +2 more sources
Functional Segregation of Pancreatic Microcirculation Reveals Sex‐Dependent Microhemodynamic Signatures [PDF]
Pancreatic exocrine microcirculation exhibits sexual dimorphism arising from steroid–genetic interactions. Laser Doppler flowmetry combined with wavelet analysis identifies a male passive coupling phenotype aligned with systemic pressure and a female active vasomotion phenotype driven by ERβ‐mediated, NO‐dependent oscillations.
Li Y +8 more
europepmc +2 more sources
Assessment of hemodynamics of the hand arteries and skin microcirculation in Dupuytren's contracture stages 3 to 4 of before and after surgical treatment with the use of Ilizarov transosseous fixation [PDF]
Purpose Hemodynamics of the hand arteries and microcirculation of the skin in patients with Dupuytren's contracture in grades 3-4 at the stages of treatment with the use of transosseous fixation was analyzed.
Tamara I. Dolganova +3 more
doaj +1 more source
Effects of Quanduzhong Jiaonang on microcirculatory blood perfusion of intestinal wall in spontaneously hypertensive rats [PDF]
Objective To investigate the effects of Quanduzhong Jiaonang(QDZJN) and pinoresinol diglucoside (PDG) on microcirculatory blood perfusion in intestinal wall and its spectral characteristics in spontaneously hypertensive rats (SHRs).
WANG Qin, ZHANG Xiaoyan, LIU Xueting, Li Bingwei, LI Hongwei, YANG Yili, HAN Jianqun
doaj +1 more source
Abstract Objective Post‐hepatectomy liver failure (PHLF) is the main limitation of extended liver resection. The molecular mechanism and the role of leukocytes in the development of PHLF remain to be unveiled. We aimed to address the impact of serine proteases (SPs) on the acute phase after liver resection by intravitally analyzing leukocyte ...
Yunjie Zhang +6 more
wiley +1 more source

