Algorithm‐Based Common Microcirculatory Framework for Monitoring and Visualizing the Integrated Pancreatic Microcirculation in Type 2 Diabetes Mellitus Mice [PDF]
Journal of DiabetesBackground Recent research has challenged the viewpoint that pancreatic islets operate independently of surrounding exocrine tissues, revealing a bidirectional blood flow between the endocrine and exocrine pancreas.
Yuan Li +10 more
doaj +3 more sources
Alendronate reduces periosteal microperfusion in vivo [PDF]
Heliyon, 2023 Objectives: Bisphosphonates are known to induce a severe adverse effect known as medication-related osteonecrosis of the jaw (MRONJ). Previous studies have proven the impact of bisphosphonates on microperfusion; therefore, this study aimed to investigate
Danielle N. Kundert +6 more
doaj +5 more sources
Skin Microhemodynamics and Mechanisms of Its Regulation in Type 2 Diabetes Mellitus. [PDF]
Biophysics (Oxf), 2022 The review presents modern ideas about peripheral microhemodynamics, approaches to the ana-lysis of skin blood flow oscillations and their diagnostic significance. Disorders of skin microhemodynamics in type 2 diabetes mellitus (DM) and the possibility of their interpretation from the standpoint of external and internal interactions between systems of ...
Tikhonova IV +3 more
europepmc +4 more sources
Leukocyte margination in alveolar capillaries: Interrelationship with functional capillary geometry and microhemodynamics [PDF]
Journal of Vascular Research, 1999 The pulmonary capillary microvasculature harbors a large pool of intravascularly marginated leukocytes. In this study, we investigated the interrelationship of leukocyte margination with characteristics of functional capillary geometry and ...
Goetz, Alwin Eduard +2 more
core +5 more sources
Tonicity and colloid osmotic pressure drive microvascular recovery from low volume hypotensive resuscitation from hemorrhagic shock [PDF]
Resuscitation PlusHypertonic saline solution containing 7.5% sodium chloride provides rapid intravascular volume expansion during severe hypovolemic shock, reducing the total fluid required to restore perfusion.
Carlos Munoz +7 more
doaj +2 more sources
Blood gas analysis as a surrogate for microhemodynamic monitoring in sepsis. [PDF]
World J Emerg Med, 2023 Emergency patients with sepsis or septic shock are at high risk of death. Despite increasing attention to microhemodynamics, the clinical use of advanced microcirculatory assessment is limited due to its shortcomings. Since blood gas analysis is a widely used technique reflecting global oxygen supply and consumption, it may serve as a surrogate for ...
Wang J, Weng L, Xu J, Du B.
europepmc +3 more sources
Foundations and Advancements in Hemodynamic Monitoring: Part II - Advanced Parameters and Tools [PDF]
Turkish Journal of Anaesthesiology and ReanimationAdvanced hemodynamic monitoring has revolutionized perioperative medicine and critical care by providing comprehensive insights into cardiovascular physiology and facilitating precise assessment and management of complex parameters such as cardiac output,
Muhammed Enes Aydın +7 more
doaj +2 more sources
Noninvasive label-free imaging of microhemodynamics by optical-resolution photoacoustic microscopy [PDF]
Optics Express, 2009 In vivo microcirculatory imaging facilitates the fundamental understanding of many major diseases. However, existing techniques generally require invasive procedures or exogenous contrast agents, which perturb the intrinsic physiology of the ...
Hu, Song +2 more
core +4 more sources
Hepatocyte-specific HIF-1α ablation improves obesity-induced glucose intolerance by reducing first-pass GLP-1 degradation. [PDF]
Sci Adv, 2019 The decrease in incretin effects is an important etiologic component of type 2 diabetes with unknown mechanisms. In an attempt to understand obesity-induced changes in liver oxygen homeostasis, we found that liver HIF-1α expression was increased mainly ...
Lee YS +3 more
europepmc +3 more sources
Effects of Dimephosphone on skin survival in conditions of reduced blood circulation [PDF]
Research Results in Pharmacology, 2018 Introduction: The search for and creation of drugs with dermatoprotective and metabotropic activity is one of the priorities of modern diabetology. Synthetic organophosphorus compounds with no anticholinesterase activity, to which Dimephosphone belongs ...
Pavel Galenko-Yaroshevsky +6 more
doaj +7 more sources