Pituitary Adenylate-Cyclase Activating Polypeptide Regulates Hunger- and Palatability-Induced Binge Eating [PDF]
Frontiers in Neuroscience, 2016 While pituitary adenylate cyclase activating polypeptide (PACAP) signaling in the hypothalamic ventromedial nuclei (VMN) has been shown to regulate feeding, a challenge in unmasking a role for this peptide in obesity is that excess feeding can involve ...
Matthew M. Hurley +10 more
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Head-Mounted Display-Based Microscopic Imaging System with Customizable Field Size and Viewpoint
Sensors, 2020 In recent years, the use of microinjections has increased in life science and biotechnology fields; specific examples include artificial insemination and gene manipulation.
Tadayoshi Aoyama +3 more
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The pedunculopontine tegmentum controls renal sympathetic nerve activity and cardiorespiratory activities in nembutal-anesthetized rats. [PDF]
PLoS ONE, 2017 Elevated renal sympathetic nerve activity (RSNA) accompanies a variety of complex disorders, including obstructive sleep apnea, heart failure, and chronic kidney disease.
Anne M Fink +3 more
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Microinjecting Cells Using a Constant-Flow Microinjection System [PDF]
Cold Spring Harbor Protocols, 2011 INTRODUCTIONThe efficient delivery of exogenous DNA to cells for expression and function studies is an essential technique of modern cell biology, and direct delivery of genetic material by microinjection remains a reliable means of transfection. In the system described here a constant flow of sample is delivered from the tip of the pipette, and the ...
Joshua Z. Gasiorowski, David A. Dean
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Components of a Microinjection System [PDF]
Cold Spring Harbor Protocols, 2011 INTRODUCTIONDirect-pressure microinjection with a micropipette is an essential tool for introducing a variety of impermeant substances into the cytoplasm or nucleus of plant and animal cells. Microinjection remains the most direct method to gain insight into the function and dynamics of intracellular components, to produce transgenic animals, or to ...
Gary G. Borisy +2 more
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Behavioral and cardiorespiratory responses to bilateral microinjections of oxytocin into the central nucleus of amygdala of Wistar rats, an experimental model of compulsion. [PDF]
PLoS ONE, 2014 INTRODUCTION:The central nucleus of amygdala plays an important role mediating fear and anxiety responses. It is known that oxytocin microinjections into the central nucleus of amygdala induce hypergrooming, an experimental model of compulsive behavior ...
Érica Maria Granjeiro +8 more
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Sleep Science, 2021 Melanin concentrating hormone (MCH) is a sleep-promoting neuromodulator synthesized by neurons located in the postero-lateral hypothalamus and incerto-hypothalamic area.
Claudia Pascovich +7 more
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Inhibition of Food Intake by PACAP in the Hypothalamic Ventromedial Nuclei is Mediated by NMDA Receptors [PDF]
, 2014 Central injections of pituitary adenylate cyclase-activating polypeptide (PACAP) into the ventromedial nuclei (VMN) of the hypothalamus produce hypophagia that is dependent upon the PAC1 receptor; however, the signaling downstream of this receptor in the
Choi, Sujean +3 more
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Journal of Integrative Neuroscience, 2023 Background: Training with inescapable shock (IS; uncontrollable stressor) is followed by significant decreases in rapid eye movement sleep (REM). However, controllability is important in the effects of stress.
Laurie L. Wellman +4 more
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The Effects of Topiramate Applied to the Nucleus Accumbens Region on Morphine Withdrawal Syndrome
Namık Kemal Tıp Dergisi, 2020 Aim:Nucleus accumbens, one of the nuclei of the basal ganglia, and dopamine, the neurotransmitter play a critical role in opioid dependence and withdrawal. In opioid withdrawal, the importance of neurotransmitters such as glutamate and gamma aminobutyric
Songül ÖZKULA +9 more
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