Involvement of orexin type-2 receptors in genetic absence epilepsy rats
IntroductionOrexin is a neuropeptide neurotransmitter that regulates the sleep/wake cycle produced by the lateral hypothalamus neurons. Recent studies have shown the involvement of orexin system in epilepsy.
Aylin Toplu +14 more
doaj +1 more source
IL-4 Inhibits IL-1β-Induced Depressive-Like Behavior and Central Neurotransmitter Alterations [PDF]
It has been known that activation of the central innate immune system or exposure to stress can disrupt balance of anti-/proinflammatory cytokines. The aim of the present study was to investigate the role of pro- and anti-inflammatory cytokines in the ...
An, Kyungeh +5 more
core +4 more sources
Nitric oxide modulation of glutamatergic, baroreflex, and cardiopulmonary transmission in the nucleus of the solitary tract [PDF]
The neuromodulatory effect of NO on glutamatergic transmission has been studied in several brain areas. Our previous single-cell studies suggested that NO facilitates glutamatergic transmission in the nucleus of the solitary tract (NTS).
Colombari, Eduardo +3 more
core +2 more sources
Antinociceptive Effect of Morphine Microinjections into the Dorsal Hippocampus in the Formalin-Induced Orofacial Pain in Rats [PDF]
In the present study, the effects of intra-hippocampal microinjections of morphine (an opioid agonist) and naloxone (an opioid antagonist) were investigated in the formalin-induced orofacial pain in rats.
Emad Khalilzadeh +3 more
doaj
Purpose To reveal a possible effect of platelet-rich plasma (PRP) on healing and histostructure of extended fasciocutaneous flaps with axial blood supply Materials and methods A flap based on the superficial inferior epigastric artery (SIEA) and extended
Natal'ia A. Shchudlo +3 more
doaj +1 more source
Hypothalamic excitatory amino acid receptors mediate stress-induced tachycardia in rats [PDF]
The role of hypothalamic excitatory amino acid (EAA) receptors in mediating the cardiovascular response to stress was examined using conscious chronically instrumented rats.
DiMicco, Joseph A., Soltis, Robert P.
core +2 more sources
Wide-field Optical Imaging of Intrinsic Signals (OI-IS; Grinvald et al., 1986) is a method for imaging functional brain hemodynamic responses, mainly used to image activity from the surface of the cerebral cortex.
Victor M. Mocanu +5 more
doaj +1 more source
We have previously shown that the caudal ventral respiratory group (cVRG) is a possible site of action of some antitussive drugs and plays a crucial role in determining both the expiratory and inspiratory components of the cough motor pattern.
Elenia eCinelli +3 more
doaj +1 more source
Human neural stem cell transplantation in ALS: initial results from a phase I trial [PDF]
We report the initial results from a phase I clinical trial for ALS. We transplanted GMP-grade, fetal human neural stem cells from natural in utero death (hNSCs) into the anterior horns of the spinal cord to test for the safety of both cells and ...
Bernardini, Laura +40 more
core +2 more sources
Deficiency of GABAergic synaptic inhibition in the Kölliker-Fuse area underlies respiratory dysrhythmia in a mouse model of Rett syndrome [PDF]
Life threatening breathing irregularity and central apnoeas are highly prevalent in children suffering from Rett syndrome. Abnormalities in inhibitory synaptic transmission have been associated with the physiopathology of this syndrome, and may underlie ...
Abdala, Ana Paula +4 more
core +2 more sources

