Results 211 to 220 of about 23,778 (281)

AMPA Receptor Within the Prelimbic Cortex Regulates Propofol-Induced Locomotor Sensitization. [PDF]

Addict Biol
Pan C, Mao X, Jiang Y, Jiang C, Qiu J, Zhang Y, Chen G, Xu M, Li J, Wu B.   +9 more
europepmc   +1 more source

A Novel Zebrafish Liver‐Specific Metastasis Model Reveals c‐Met as a Driver of Liver Tropism

Liver International, Volume 46, Issue 4, April 2026.
ABSTRACT Background and Aims Intrahepatic metastasis negatively impacts the prognosis of several cancers, including hepatocellular and colorectal carcinoma. Zebrafish larval xenografts serve as a robust vertebrate platform that allows direct visualisation of tumour behaviour within a living organism.
Merve Basol, Peyda Korhan, Helin Ozaktas, Nese Atabey, Gulcin Cakan‐Akdogan   +4 more
wiley   +1 more source

Strain, procedures, and tools for reproducible genetic transformation and genome editing of the emerging plant model Spirodela polyrhiza

New Phytologist, Volume 250, Issue 2, Page 735-756, April 2026.
Summary Duckweeds (Lemnaceae) have excellent potential for fundamental and applied research due to ease of cultivation, small size, and continuous fast clonal growth. However, their usage as model organisms and platforms for biotechnological applications is often limited by the lack of universal genetic manipulation methods necessary for transgene ...
Verónica Barragán‐Borrero, Amanda de Santana Lopes, Enrico Diniz Rodrigues Batista, Martin Höfer, Rana Elias, Abhisek Chakraborty, Arturo Ponce‐Mañe, Clotilde Descombes, Laura Diezma‐Navas, Lydia Petraki, Meret Huber, Shuqing Xu, Arturo Marí‐Ordóñez   +12 more
wiley   +1 more source

From Covalent Traps to Fluorescent Beacons: The Expanding Arsenal of Chemical Probes for Studying Ubiquitin and Ubiquitin‐Like Proteins

Angewandte Chemie, Volume 138, Issue 13, 23 March 2026.
A large variety of chemistry‐based ubiquitin probes have been developed. ABSTRACT Ubiquitin (Ub) and ubiquitin‐like proteins (Ubls) orchestrate diverse cellular processes through reversible post‐translational modification of target proteins. Their conjugation is governed by a cascade of E1 activating, E2 conjugating, and E3 ligating enzymes, while ...
Saibal Chanda, Wenshe Ray Liu
wiley   +2 more sources

Natural genetic variation quantitatively regulates heart rate and dimension. [PDF]

Nat Commun
Gierten J, Welz B, Fitzgerald T, Thumberger T, Agarwal R, Hummel O, Leger A, Weber P, Naruse K, Hassel D, Hübner N, Birney E, Wittbrodt J.   +12 more
europepmc   +1 more source

Noradrenergic regulation of skeletal muscle oxygen pressures: Impact of heart failure with preserved ejection fraction and heat therapy

Experimental Physiology, Volume 111, Issue 4, Page 1875-1890, 1 April 2026.
Abstract Attenuation of sympathetic vasoconstriction during exercise (functional sympatholysis) contributes to skeletal muscle oxygen delivery–utilization matching. However, the extent to which muscle contractions impact noradrenergic regulation of interstitial oxygen pressures (PO2is${P_{{{\mathrm{O}}_2}}}_{{\mathrm{is}}}$; the driving force for blood–
Edward T. N. Calvo, Jacob M. Pontorno, Benjamin Zeidler, Taciane M. M. Pejon, Michael D. Belbis, Scott K. Ferguson, Craig J. Goergen, Timothy P. Gavin, Bruno T. Roseguini, Igor A. Fernandes, Daniel M. Hirai   +10 more
wiley   +1 more source

Region-specific neuroadaptations of CRF1 and CRF2 expression following heroin exposure in female rats. [PDF]

Pharmacol Biochem Behav
Schneider P, Goldbaum D, Agarwal A, Taylor A, Sundberg P, Gardner EL, Ranaldi R, You ZB, Galaj E.   +8 more
europepmc   +1 more source

The sympathoregulatory region of the mouse rostral brainstem relies on both GABA and glycine to generate inhibitory currents

The Journal of Physiology, Volume 604, Issue 7, Page 2939-2957, 1 April 2026.
Abstract figure legend Our study demonstrates that both GABA and glycine mediate inhibitory postsynaptic currents in the ventrolateral/ventromedial medulla (VLM/VMM) and increasing the activity of inhibitory synapses facilitates glycine release. We found that presympathetic VLM/VMM neurons receive glycinergic inputs, which release both glycine and GABA,
Hong Gao, Lucie D. Desmoulins, Adrien J. R. Molinas, Courtney M. Dugas, Andrea Zsombok, Andrei V. Derbenev   +5 more
wiley   +1 more source

Effects of microinjections of nicotine into the dorsal hippocampus on morphine- induced amnesia

Annals of General Psychiatry, 2008
Zarrindast Mohammad Reza, Rezayof Ameneh, Khajepour Lotfollah   +2 more
doaj   +1 more source