Results 141 to 150 of about 11,396 (262)

ROS-responsive tegafur-pheophorbide a conjugate-loaded microneedles for deep drug delivery and chemo-photodynamic therapy of superficial tumors. [PDF]

Int J Pharm X
Li A, Ma Y, Dai Y, Guo Y, He Y, Chen S, Su X, Fang C, Chen L, Duan M, Chen M, Ren J, Wang L, Wang C, Zhang Z.   +14 more
europepmc   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Recent advances in dissolving microneedles for breast cancer immunotherapy: local delivery and tumor microenvironment remodeling. [PDF]

Front Immunol
Chen Y, Song L, Zhu Y, Zhang Z, Lu Y, Wang X, Pang H.   +6 more
europepmc   +1 more source

Amphibian‐Derived Peptide OA‐AL14 Alleviates UVB‐Induced Skin Photoaging via Autophagy Activation Mediated by the AMPK/mTOR Pathway

Integrative Zoology, EarlyView.
The schematic diagram illustrates that the amphibian‐derived peptide OA‐AL14 protects against UVB‐induced skin photoaging through a dual mechanism: activating the Nrf2 pathway to counteract oxidative stress and modulating the AMPK/mTOR axis to induce protective autophagy. ABSTRACT Skin photoaging, primarily driven by ultraviolet B (UVB) radiation, is a
Ying Peng, Yutong Wu, Zhe Fu, Zijian Kang, Qiuye Jia, Wenbi Zhao, Ziyi Wang, Yuexi Liu, Ruijie Zhang, Yuansheng Li, Zeqiong Ru, Wenrou Su, Naixin Liu, Yilin Li, Saige Yin, Ying Wang, Xinwang Yang   +16 more
wiley   +1 more source

Combined electrospun fibre-microneedle patches for enhanced transmucosal delivery of benzodiazepines and proteins.

Biomater Sci
Berry C, Edmans JG, Slowik KM, Byers RA, Danby S, Hatton PV, Murdoch C, Colley HE.   +7 more
europepmc   +1 more source

Reconstructing protein conformations to activate follicular enzyme-nutrient reservoirs for reversing follicle aging. [PDF]

Bioact Mater
Ling S, Liu M, Meng C, Huo K, Wang Y, Zhang Y, Wei Y, Zhou L, Du Y, Cui W.   +9 more
europepmc   +1 more source

The oral microbiota and periodontal health in orthodontic patients

Periodontology 2000, EarlyView.
Abstract The oral microbiota develops within the first 2 years of childhood and becomes distinct from the parents by 4 years‐of‐age. The oral microbiota plays an important role in the overall health/symbiosis of the individual. Deviations from the state of symbiosis leads to dysbiosis and an increased risk of pathogenicity.
Brandon W. Peterson, Geerten‐Has Tjakkes, Anne‐Marie Renkema, David J. Manton, Yijin Ren   +4 more
wiley   +1 more source

Advances in microneedle design for the delivery of drugs, proteins, and cells in the treatment of hypertrophic scars. [PDF]

Burns Trauma
Guo J, Tang Q, Ge Z, Xia Q, Liu H, Shi H, Huang J, Chen J, Cooper MS, Yan X, Yang C, Wang Y.   +11 more
europepmc   +1 more source

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source

Ion-Responsive Microneedles Delivering Subtype-Specific Mitochondrial Extracellular Vesicles from HEY1⁺ Cardiomyocytes for Cardiac Repair in Bama Minipigs with Myocardial Ischemia-Reperfusion Injury. [PDF]

Theranostics
Qu P, Shi J, Li X, Gu Y, Liu J, Zhang H, Zhou M, Ma C, Li X, Tian W, Liang Q, Li G, Cheng P.   +12 more
europepmc   +1 more source