Results 151 to 160 of about 11,396 (262)

Understanding exosomes in diabetic wound healing

Periodontology 2000, EarlyView.
Abstract Background Diabetic wounds signify a major complication of diabetes mellitus, characterized by chronic inflammation, compromised angiogenesis, and high risk of infection, amputation, and mortality. Contemporary therapies remain limited in efficacy and durability.
Paras Ahmad, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +4 more
wiley   +1 more source

Dissolving Microneedles Loaded with Lipid Nanocarriers for Vaginal Delivery of Clotrimazole: <i>In Vitro</i> and <i>Ex Vivo</i> Evaluation. [PDF]

Mol Pharm
Udayakumar P, Škalko-Basnet N, Rondahl V, Cotaquispe CFS, Hemmingsen LM, Sotiriou GA, Du J, Teleki A.   +7 more
europepmc   +1 more source

Understanding Exosomes in Hair Regeneration

Periodontology 2000, EarlyView.
Abstract Background Alopecia is a prevalent condition correlated with significant psychosocial challenges, while contemporary treatments exhibit variable efficacy, require extended use, and may cause adverse effects. This review aimed to comprehensively assess exosome‐mediated interventions as a novel cell‐free regenerative approach for hair ...
Paras Ahmad, Catherine Davies, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Development and Validation of a UV-Vis Spectrophotometric Method for the Determination of Hispidulin, Verbascoside, and Isoverbascoside in Sesewanua (<i>Clerodendrum Fragrans</i> Willd.) Fraction and Its Application to Dissolving Microneedle Formulations. [PDF]

ACS Omega
Sapiun Z, S Mohamad SNF, Imran AK, Kamba V, Wicita PS, Jahja SR, Yunus FAM, Mukhriani M, Daud RPA, Rasyid FA, Paneo MA, Ysrafil Y, Masrif M, Pangalo P.   +13 more
europepmc   +1 more source

Techniques for subretinal injections in animals

Veterinary Ophthalmology, Volume 28, Issue 2, Page 506-518, March 2025.
Abstract Subretinal injections are not commonly performed during clinical treatment of animals but are frequently used in laboratory animal models to assess therapeutic efficacy and safety of gene and cell therapy products. Veterinary ophthalmologists are often employed to perform the injections in the laboratory animal setting, due to knowledge of ...
Ryan F. Boyd, Simon M. Petersen‐Jones
wiley   +1 more source

Microneedles meet photomedicine: emerging strategies for diagnosis and therapy of skin diseases. [PDF]

Nanoscale Adv
Zhou Z, Li Y, Guo M, Zhao X, Ma L, Meng Q, Deng H.   +6 more
europepmc   +1 more source

Advancing Type 1 Diabetes Treatment: 3 PM‐Oriented Innovations in Islet Transplantation and Biomaterial Engineering

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Type 1 Diabetes (T1D) is an autoimmune disorder marked by the immune‐mediated destruction of pancreatic β‐cells, resulting in insulin deficiency and dysregulated glucose control. Current therapies—such as insulin replacement and artificial pancreas systems—manage symptoms but fail to restore endogenous β‐cell function or halt disease ...
Fatemeh Sabet Sarvestani, Ramin Yaghobi, Mohsen Khosravi Maharlooei, Mehdi Golshan, Mohammad Hossein Karimi   +4 more
wiley   +1 more source

Technical challenges and quality considerations for dissolving microneedles. [PDF]

Int J Pharm
Kamal NS, Acheampong S, Zaman RU, Strasinger C, Clark AG, Zhu A, Tang Y, Zidan A, Ashraf M.   +8 more
europepmc   +1 more source

Fish Scales: A Multifunctional Biomaterial from Nature

ENERGY &ENVIRONMENTAL MATERIALS, Volume 9, Issue 5, September 2026.
Fish scales demonstrate nature's solution to impact protection through overlapping multilayered architecture. This biological design combines mineralized surfaces with collagen networks to achieve both flexibility and fracture resistance. The structural principles inspire advanced protective materials and biomedical implants, where damage tolerance ...
Liyao Dong, Xiaojie Sun, Xiguang Chen
wiley   +1 more source

Advanced azelaic acid hyalubilosome-loaded microneedles for potent anti-inflammatory, antioxidant, and antimicrobial for Acne treatment by up-regulation of Nrf2/HO-1 signaling pathway. [PDF]

Int J Pharm X
Elhabal SF, Elrefai MFM, Hassan FE, Tolba NS, El Galil RMA, Morsy SAA, Allam S, Emam AM, Wanas H, Azer MS, Ahmed MM, Abdelmoneim HA, Fady M, Hamdan AME.   +13 more
europepmc   +1 more source