FEA-guided co-design of bubble microneedles: controlled tip separation for rapid transdermal and sublingual delivery. [PDF]
Jiang C +10 more
europepmc +1 more source
The review discusses stimuli‐responsive hydrogels as soft optical materials that translate physical, chemical, and biological cues into refractive‐index, scattering, birefringence, diffraction, and transparency changes. It examines major stimulus classes and photonic architectures for biosensing, waveguiding, adaptive lenses, smart windows, and therapy.
Andrés Bernal‐Ballén +2 more
wiley +1 more source
A ROS-responsive core-shell microneedle platform integrating sonodynamic gas antibacterial therapy and modulating immunity for diabetic wound healing. [PDF]
Wang P +11 more
europepmc +1 more source
Integrating Oncolytic Virus Engineering and Delivery Strategies for Enhanced Cancer Virotherapy
Integrated engineering strategies combining oncolytic virus (OV) design with advanced delivery platforms overcome biological barriers and enhance cancer virotherapy. Genetic engineering improves viral potency and selectivity, while local and systemic delivery systems promote viral protection, tumor targeting, penetration, and tumor microenvironment ...
Jiliang Zhao +5 more
wiley +1 more source
An engineered intradermal microneedle-array device enhances the cellular immune responses in a guinea pig model. [PDF]
Nepveu-Traversy ME +7 more
europepmc +1 more source
In this study, we investigate the dynamics of glucose diffusion between subcutaneous tissue and hydrogel‐filled microneedles. Specifically, we examine how hydrogel thickness, microneedle size, and glucose concentration influence diffusion. This study provides an experimental reference to the wearable biosensor community researching microneedle‐based ...
Wensheng Lin +9 more
wiley +1 more source
A programmable bioresorbable electrochemical microneedle sensor array for perioperative monitoring of organ health. [PDF]
Li X +9 more
europepmc +1 more source
ABSTRACT Electroporation‐based biopsy (e‐biopsy) enables minimally invasive extraction of tissue proteins without excision; however, the effective diffusion from tissue into the sampling medium, a key parameter required for this procedure, has not been quantified in human tissues. We coupled time‐resolved aqueous sampling with a one‐dimensional Fickian
Amir Duenyas +6 more
wiley +1 more source
The Influence of Mask Modification on Microneedle Strength in Deep X-Ray Lithography. [PDF]
Wang J, Li Y, Du L.
europepmc +1 more source
Ferroptosis in breast cancer: From adipocyte–immune–iron regulation to therapeutic application
Ferroptosis in breast cancer is regulated by an integrated adipocyte–immune–iron network rather than by tumour‐intrinsic pathways alone. Adipocyte‐derived lipid substrates and redox metabolites, immune‐cell‐mediated cytokine signalling and iron‐dependent oxidative stress collectively shape a dynamic ferroptosis ecosystem that can shift tumours towards ...
Juan Sun, Yang Qu, Ru Yao, Yidong Zhou
wiley +1 more source

