Results 191 to 200 of about 11,396 (262)

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

Phytotherapy Research, Volume 40, Issue 8, Page 4759-4791, August 2026.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee, Yu Jin So, Il‐Joo Jo, Ji Yong Jang, Tae Han Yook, Jun Ho Lee, Sung Wook Kim, Kangwook Lee, Soo Jung Park, Gabsik Yang   +9 more
wiley   +1 more source

An engineered intradermal microneedle-array device enhances the cellular immune responses in a guinea pig model. [PDF]

Front Immunol
Nepveu-Traversy ME, Babuadze GG, Potterton D, de La Vega MA, Alajbegovic A, Julien J, Winterborn A, Kobinger G.   +7 more
europepmc   +1 more source

Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death

Phytotherapy Research, Volume 40, Issue 8, Page 5119-5131, August 2026.
ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi, Renda Chahna, Francesca Maffei, Alma Martelli, Vincenzo Calderone, Carmela Fimognari, Eleonora Turrini   +6 more
wiley   +1 more source

A programmable bioresorbable electrochemical microneedle sensor array for perioperative monitoring of organ health. [PDF]

Nat Biomed Eng
Li X, Liu S, Mo J, Yang C, Li G, Zhou M, Ryu J, Morales M, Fang H, Ouyang W.   +9 more
europepmc   +1 more source

Biomaterial‐Integrated Electroporation for Therapeutic Delivery: From Gene Editing to Tumor Ablation and Immune Modulation

Small, Volume 22, Issue 45, 13 August 2026.
Biomaterial‐integrated electroporation establishes a programmable therapeutic interface that coordinates electric‐field modulation, transient or irreversible membrane permeabilization, cargo stabilization, and immune remodeling. This Review highlights how nanocarriers, hydrogels, and bioelectronic interfaces expand electroporation from conventional ...
Binbin Ji, Zhuozhuo Wu, Yuyue Jiang, Xiaoyu Liu, Jingfeng Li, Fengkuo Xu, Chaojie Li, Qungang Shan, Ziyin Wang, Junhao Wang, Wei Huang, Yaping Zhuang, Wenguo Cui, Zhongmin Wang   +13 more
wiley   +1 more source

Biphasic dissolving microneedles with cyclodextrin inclusion complexes for enhanced delivery of poorly soluble drugs. [PDF]

RSC Adv
Wang R, Cao J, Zou J, Zhang R, Li M, Zhang W, Guo M.   +6 more
europepmc   +1 more source

Regenerative Microbiology: Harnessing Bacterial Antagonism and Spatiotemporal Signaling for Diabetic Wound Repair

Smart Medicine, Volume 5, Issue 4, August 2026.
This review introduces “Regenerative Microbiology,” a framework that uses bacterial antagonism and phage therapy to address diabetic wound dysbiosis. By activating the p40/EGFR/PI3K axis and providing a vascular‐stratified precision roadmap, this approach shifts the paradigm from antimicrobial suppression to intelligent, microbe‐driven tissue ...
Sabri Saeed Sanabani
wiley   +1 more source

The Influence of Mask Modification on Microneedle Strength in Deep X-Ray Lithography. [PDF]

Micromachines (Basel)
Wang J, Li Y, Du L.
europepmc   +1 more source

Microenvironment‐Responsive Drug Delivery Systems for Ocular Surface Diseases: Mechanisms, Applications, and Translational Challenges

Small Science, Volume 6, Issue 8, August 2026.
Microenvironment‐responsive drug delivery systems overcome ocular physiological barriers by responding to temperature, pH, ions, reactive oxygen species, and enzymes. This review bridges material design, performance evaluation, and clinical translation, offering actionable insights for treating dry eye disease, infectious keratitis, and corneal ...
Jiamin Liu, Liangbo Chen, Yao Fu, Siyi Zhang   +3 more
wiley   +1 more source

A magnetically actuated robotic capsule endoscope for in-situ visualization and microneedle-mediated targeted drug delivery in gastrointestinal tract. [PDF]

Microsyst Nanoeng
Chen W, Sui J, Cao X, Huang J, Chen F, Zhao K, Li Y, Liu X, Yuan Z, Zhang J, Jiang L, Xie X, Wang C.   +12 more
europepmc   +1 more source