Flexible microneedle array with AuNPs/MXene for visualized electrochemical monitoring of osteosarcoma miR-181b. [PDF]
Zhu ZS +7 more
europepmc +1 more source
A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh +11 more
wiley +1 more source
Wireless light-gated photoelectrochemical microneedle wearables for zero-bias longitudinal monitoring in interstitial fluid. [PDF]
Wang H +9 more
europepmc +1 more source
Propolis-Based Microneedles Incorporating Neratinib-Loaded <i>Ocimum basilicum</i> Essential Oil-Based Lipid Nanovesicles for Minimally Invasive Cancer Therapy: Formulation and In Vivo Evaluation in an Ehrlich Solid Tumor Model. [PDF]
Elhabal SF +11 more
europepmc +1 more source
3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi +4 more
wiley +1 more source
Patterned Screen‐Printing Process for Substrate‐Free and Scalable Hyaluronic Acid Microneedle Arrays
A substrate‐free microneedle array comprising a hybrid hyaluronic acid ink was fabricated via a scalable screen‐printing process for flexible transdermal drug delivery. Defect‐free mold filling was achieved using a vacuum‐assisted jig and a delayed drying system, and the use of this versatile platform for multi‐drug patterning and ex vivo skin ...
Sanghyun Ahn +3 more
wiley +1 more source
Hyaluronic acid-based osmolality-responsive immediate-release microneedles co-loading baicalein and astaxanthin for oral ulcer therapy. [PDF]
Yang J +11 more
europepmc +1 more source
Cortisol Dynamics at High Temporal Resolution For Wearable Biosensor Research
High‐frequency cortisol profiling reveals that endocrine responses depend strongly on both stressor type and the individual. Circadian sampling shows a consistent morning‐to‐evening decline, while cold exposure elicits delayed rises and exercise and cognitive challenges produce divergent trajectories.
Munia Ferdoushi +3 more
wiley +1 more source
pH- and Near-Infrared Light Dual-Responsive Hydrogel Microneedles Incorporating Polydopamine-Based Curcumin-Loaded Nanoparticles for Antibacterial and Oxidative Injury Protection. [PDF]
Wang X, Wang R, Yi J, Wang Y, Wei G.
europepmc +1 more source
From Molecular Targets to Advanced Delivery Systems: Aptamers for Precision Ocular Therapeutics
Aptamer‐based strategies are revolutionizing ocular disease management through highly specific molecular recognition of disease specific molecular targets. This review systematically integrates therapeutic aptamer sequences, diagnostic aptasensor platforms, and targeted delivery strategies, highlighting design principles, ocular bioavailability ...
Minal Thacker +4 more
wiley +1 more source

