Results 91 to 100 of about 12,393 (293)

Synergistic immunoreaction of acupuncture-like dissolving microneedles containing thymopentin at acupoints in immune-suppressed rats

Acta Pharmaceutica Sinica B, 2018
Dissolving microneedles carried drug molecules can effectively penetrate the stratum corneum of skin to improve the transdermal drug delivery. The traditional Chinese medicine acupuncture is based on the needle stimulation at a specific location ...
Qian Zhang, Chuncao Xu, Shiqi Lin, Huanbin Zhou, Gangtao Yao, Hu Liu, Lili Wang, Xin Pan, Guilan Quan, Chuanbin Wu   +9 more
doaj   +1 more source

Microneedles for various ocular diseases

Eye disorders and injuries are a major clinical problem all over the world. The presence of ocular obstacles and clearance systems makes safe and effective drug administration to the eye difficult.
Dua, K, Kanojia, N, Sood, P, Puri, V, Dheer, D, Sharma, A, Thakur, N, Verma, N, Thapa, K   +8 more
core   +1 more source

Microneedles: an emerging transdermal drug delivery system

, 2011
Objectives One of the thrust areas in drug delivery research is transdermal drug delivery systems (TDDS) due to their characteristic advantages over oral and parenteral drug delivery systems.
Shital H Bariya, Tejal A Mehta, Mukesh C Gohel, Om Prakash Sharma   +3 more
core   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Microneedle-Assisted Delivery of Curcumin: Evaluating the Effects of Needle Length and Formulation

Micromachines
Dermal drug delivery presents a significant challenge for poorly soluble active compounds like curcumin, which often struggle to penetrate the skin barrier effectively.
Em-on Chaiprateep, Soma Sengupta, Cornelia M. Keck   +2 more
doaj   +1 more source

Assessment of knowledge and opinion towards microneedles technology among jordanian pharmacists [PDF]

Pharmacia
Background: Microneedles are an innovative, patient-friendly, minimally invasive, and self-administered drug delivery system that has garnered significant attention.
Juhaina M. Abu Ershaid, Ola Tarawneh, Abdallah Y. Naser   +2 more
doaj   +3 more sources

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

Advanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, Youqiang Su, Wei Ren, Xiang Li, Changjiu He   +13 more
wiley   +1 more source

Drug delivery through microneedles

, 2016
\u3cp\u3eDrug delivery through microneedles is a new form of a pharmaceutical dosage system. While single microneedles have been clinically applied already, the out-of-plane integration of a multitude of microneedles in a pharmaceutical patch is a ...
Luttge, R., Lüttge, R Regina, R. Luttge
core   +2 more sources

Stimuli-responsive microneedles: Engineered solutions for multifaceted diabetic wound healing

Journal of Applied Biomaterials & Functional Materials
Diabetic wounds are among the most common complications in patients with diabetes, often occurring in the lower extremities and manifesting as diabetic foot ulcers.
Fengyuan Wang, Jue Zhang, Bing Han, Ming Chen, Xiyu Wang, Ke Wang, Jiaxi Kou, Guopu Chen, Fenghua Sun   +8 more
doaj   +1 more source

Solid Ethanol as a Renewable, Low‐Toxicity, Electron‐Beam Direct Write, and Biomedical Material

Advanced Science, EarlyView.
3D ice lithography (3DIL) enables the fabrication of intricate submicrometer objects using ethanol as a renewable starting material. This study combines process optimization, structural and material analysis, and biomedical applications, from cell culture scaffolds to the patterning of neurostimulation electrodes, demonstrating performance in both in ...
Bruno Perdigão, Bingdong Chang, Gwendoline A. E. Anand, Lechan Tao, Kayeon Kim, Anne Zebitz Eriksen, Malte Alexander Schönhoff, Guilherme Ferreira, Xiyuan Liu, Su Genelioglu, Joachim Lyngholm‐Kjærby, Neha Zahoor, Johan Ulrik Lind, Alice Bastos da Silva Fanta, Thomas Willum Hansen, Changsi Cai, Anpan Han   +16 more
wiley   +1 more source