Results 81 to 90 of about 12,393 (293)
A scalable fabrication process of polymer microneedles
, 2012 Sixing Yang, Yan Feng, Lijun Zhang, Nixiang Chen, Weien Yuan, Tuo JinSchool of Pharmacy, Shanghai Jiao Tong University, Shanghai, People's Republic of ChinaAbstract: While polymer microneedles may easily be fabricated by casting a solution in a ...
Chen N +5 more
core
Advanced Science, EarlyView.An mRNA‐liposome vaccine via dissolving microneedles (ML‐DMN) enables efficient skin‐targeted delivery while preserving mRNA integrity and allowing sustained antigen expression. Unlike intramuscular (IM) injection, ML‐DMN engages skin‐resident immune cells, activates antigen‐presenting cells (APCs), and induces strong T cell and cytokine responses at ...
Jeehye Nam +9 more
wiley +1 more source
Nanosuspension-Based Dissolving Microneedle Arrays for Intradermal Delivery of Curcumin
Pharmaceutics, 2019 The objective of this study was to evaluate the intradermal delivery of curcumin utilising poly(vinylalcohol) (PVA)-based microneedles loaded with curcumin nanosuspension (CU-NS).
Sharif Abdelghany +5 more
doaj +1 more source
Protein encapsulation in polymeric microneedles by photolithography
, 2012 Jaspreet Singh Kochhar,1 Shui Zou,2 Sui Yung Chan,1 Lifeng Kang11Department of Pharmacy, 2Department of Chemistry, National University of Singapore, SingaporeBackground: Recent interest in biocompatible polymeric microneedles for the delivery of ...
Kochhar JS, Chan SY, Zou S, Kang L
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Microneedles for drug and vaccine delivery
, 2012 Microneedles were first conceptualized for drug delivery many decades ago, but only became the subject of significant research starting in the mid-1990's when microfabrication technology enabled their manufacture as (i) solid microneedles for skin ...
Yeu-Chun Kim, J H Park, M R Prausnitz
core +1 more source
Advanced Science, EarlyView.This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka +4 more
wiley +1 more source
Bioinspired Wet Adhesive Proanthocyanidins Microneedles for Ocular Wound Healing
ResearchMicroneedles have shown considerable potential in treating ocular diseases, yet enhancing their architecture and functionality to improve therapeutic efficacy poses marked challenges.
Bin Kong +3 more
doaj +1 more source
Microneedles for Drug Delivery [PDF]
Pharmaceutical Research, 2010 The theme section highlighted in this issue of Pharmaceutical Research provides a snapshot of the latest information on today’s microneedle research and development, predominately in transdermal applications. Fifteen original papers from academia and industry cover research and development of microneedles from concept to human clinical studies and ...
openaire +2 more sources
Revista Brasileira de Cirurgia Plástica (RBCP) – Brazilian Journal of Plastic Sugery, 2020 Introduction: Microneedling, also called percutaneous collagen induction therapy (PCIT), is a technique applied with an equipment called roller. It is suitable for rejuvenation, alopecia, all types of scars, acne, photo rejuvenation, stretch marks, skin flaccidity, melasma, expression wrinkles, and improvement of the general aspect of the skin ...
Adriana Da Silva Ferreira +2 more
openaire +2 more sources
Endogenous Engineering Reprograms Extracellular Vesicles for Enhanced Therapeutic Function
Advanced Science, EarlyView.This review explains how Extracellular vesicles‐producing cells can be endogenously engineered to load therapeutic proteins and nucleic acids. We summarize physiological and genetic strategies that harness native sorting pathways for selective cargo loading.
Jinghui Wang +10 more
wiley +1 more source