Results 71 to 80 of about 15,352 (268)
Materials & DesignThe purpose of this study was to develop innovative microneedles with drug crystallinity control for the fast or sustained release of poorly water-soluble drugs.
Mi Ran Woo +8 more
doaj +1 more source
Microneedles: an emerging transdermal drug delivery system
, 2011 Objectives One of the thrust areas in drug delivery research is transdermal drug delivery systems (TDDS) due to their characteristic advantages over oral and parenteral drug delivery systems.
Shital H Bariya +3 more
core +1 more source
Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics
Advanced Science, EarlyView.This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li +8 more
wiley +1 more source
Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair
Advanced Science, EarlyView.Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai +18 more
wiley +1 more source
MODELLING AND OPTIMISATION OF MICRONEEDLE SYSTEMS
Міжнародний науково-технічний журнал "Проблеми керування та інформатики"A mathematical model and variatinal method of optimal parameter computation for transdermal (hypodermic) drug delivery by microneedle systems are developed.
Г.В. Сандраков +3 more
doaj +1 more source
A scalable fabrication process of polymer microneedles
, 2012 Sixing Yang, Yan Feng, Lijun Zhang, Nixiang Chen, Weien Yuan, Tuo JinSchool of Pharmacy, Shanghai Jiao Tong University, Shanghai, People's Republic of ChinaAbstract: While polymer microneedles may easily be fabricated by casting a solution in a ...
Chen N +5 more
core
Preparation of particle-attached microneedles using a dry coating process
, 2022 The standard process for manufacturing microneedles containing API requires a way to process the API, including dissolving the API in a co-solvent and a drying process.
이재면
core +1 more source
Advanced Science, EarlyView.This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang +14 more
wiley +1 more source
Protein encapsulation in polymeric microneedles by photolithography
, 2012 Jaspreet Singh Kochhar,1 Shui Zou,2 Sui Yung Chan,1 Lifeng Kang11Department of Pharmacy, 2Department of Chemistry, National University of Singapore, SingaporeBackground: Recent interest in biocompatible polymeric microneedles for the delivery of ...
Kochhar JS, Chan SY, Zou S, Kang L
core
Advanced Science, EarlyView.A root‐inspired microneedle array patch uses lattice‐based mechanical interlocking to unite rigid microneedles with a flexible substrate. The interlocked rigid–soft architecture improves interfacial bonding, supports stable adhesion on curved and wet tissues under dynamic motion, and provides a versatile platform for robust biointerfacing and future ...
Jongchan Lee +9 more
wiley +1 more source