Results 61 to 70 of about 15,352 (268)

Biocompatible Microneedles.

open access: yes, 2016
ESEM images of A) Polyethylene glycol B) Polycaprolactone and C) Polyacrylic acid microneedles measuring approximately 1000μm in height and 333μm in width.
J. Christopher Luft (742626)   +9 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Two-photon polymerization of microneedles for transdermal drug delivery [PDF]

open access: yes, 2010
Microneedles are small-scale devices that are finding use for transdermal delivery of protein-based pharmacologic agents and nucleic acid-based pharmacologic agents; however, microneedles prepared using conventional microelectronics-based technologies ...
Narayan, Roger J   +9 more
core   +1 more source

Development of Microneedles for Diagnostic and Therapeutics

open access: yes, 2023
This work examines the fabrication and use of polymer microneedles made using an adapted screen printing method and UV curable polymer in both diagnostic and therapeutic applications. Starting with smaller round ended microneedles used only for cosmetics,
SARAH MCINTYRE
core   +1 more source

In Situ Genetic Engineering Facilitates MMP‐9‐Responsive TIMP1 Release Through Proteolytic Cleavage to Boost Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
This study develops an MMP‐9‐responsive protein release system that transforms resident cells into drug depots through in situ genetic engineering. Anchored to the membrane, the therapeutic protein TIMP1 is selectively released upon MMP‐9 cleavage.
Yuan Zhang   +11 more
wiley   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

open access: yesAdvanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing   +10 more
wiley   +1 more source

Hollow microneedles as a flexible dosing control solution for transdermal drug delivery

open access: yesMaterials Today Bio
Microneedles, small needle-like structures typically less than 1000 μm in length, are effective tools for transporting substances across biological barriers via minimally invasive pathways.
Jongwon Kim   +3 more
doaj   +1 more source

Introduction of anatomy of the skin and microneedles as a smart carrier for drug delivery

open access: yes
Novel drug delivery technologies and knowledge of skin anatomy have been revolutionary in healthcare. This chapter explores the intricate structure of the skin and the use of microneedles as a smart carrier for targeted drug delivery.
Dua, K   +4 more
core   +1 more source

TMPTA Microneedles of Different Shapes.

open access: yes, 2016
A) TMPTA microneedles of aspect ratio 2, 3, and 4 (left to right). 1000μm tall TMPTA microneedles with spacing of B) 0.5 base widths and C) 1.5 base widths.
J. Christopher Luft (742626)   +9 more
core   +1 more source

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

open access: yesAdvanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

Home - About - Disclaimer - Privacy