Results 101 to 110 of about 37,259 (377)

Application of microneedle-based vaccines in biosecurity

Journal of Biosafety and Biosecurity, 2022
Countries must have strong early warning, detection, and response capabilities in the face of the risks and challenges posed by major infectious diseases and bioterrorism threats.
Zhiying Jin, Baohua Zhao, Wei Wan, Yue Li, Xuexin Bai, Chenyi Hu, Jing Wang, Yanwei Li, Wenwen Xin, Lin Kang, Hao Yang, Jinglin Wang, Shan Gao   +12 more
doaj   +1 more source

Rapidly dissolving polymeric microneedles for minimally invasive intraocular drug delivery [PDF]

, 2016
In this study, dissolving microneedles (MNs) were used to enhance ocular drug delivery of macromolecules. MNs were fabricated using polyvinylpyrrolidone (PVP) polymer of various molecular weights (MWs) containing three model molecules of increasing MW ...
Ali, Ahlam, Alshammari, Farhan, Donnelly, Ryan, McCarthy, Helen, Tekko, Ismaiel, Thakur, Raghu   +5 more
core   +1 more source

Microneedles as a Promising Technology for Disease Monitoring and Drug Delivery: A Review

ACS Materials Au
The delivery of molecules, such as DNA, RNA, peptides, and certain hydrophilic drugs, across the epidermal barrier poses a significant obstacle. Microneedle technology has emerged as a prominent area of focus in biomedical research because of its ability
Rashmi Hulimane Shivaswamy, Pranav Binulal, Aloysious Benoy, Kaushik Lakshmiramanan, Nitu Bhaskar, H. Pandya   +5 more
semanticscholar   +1 more source

Hydrogel-Forming Microneedles: Current Advancements and Future Trends.

Macromolecular Bioscience, 2020
In this focused progress review, the recent developments and trends of hydrogel-forming microneedles (HFMs) and potential future directions are presented.
Joseph G. Turner, Leah R White, P. Estrela, H. Leese   +3 more
semanticscholar   +1 more source

Optimization of Printing Parameters for Digital Light Processing 3D Printing of Hollow Microneedle Arrays [PDF]

, 2021
Essyrose Mathew, Giulia Pitzanti, Ana L. Gomes dos Santos, Dimitrios A. Lamprou   +3 more
openalex   +1 more source

Customizable Fabrication of 2D and Conformal Multielectrode Arrays for 3D Printed Organotypic Bioelectronic Interfaces

Advanced Healthcare Materials, EarlyView.
Aerosol jet printing enables rapid, customizable fabrication of flexible, fully gold multi‐electrode arrays (MEAs) for organotypic bioelectronic interfaces. The printed MEAs exhibit stable electrochemical performance, cytocompatibility, and functionality in recording and stimulation, including integration with 3D‐printed constructs.
Ernest Cheah, Xinchao Gao, Wei Qi Jaw, Guo Liang Goh, Jia Min Lee, Chongquan Huang, Sing Yian Chew, Wai Yee Yeong   +7 more
wiley   +1 more source

Hydrodynamic gene delivery in human skin using a hollow microneedle device [PDF]

, 2017
Microneedle devices have been proposed as a minimally invasive delivery system for the intradermal administration of nucleic acids, both plasmid DNA (pDNA) and siRNA, to treat localised disease or provide vaccination.
Birchall, J. C., Coulman, S. A., Dayan, C., Dul, M., Henri, S., Kochba, E., Levin, Y., Malissen, B., O'Mahony, Conor, Porta, P., Serve, J., Stefanidou, M., Wong, F. S.   +12 more
core   +5 more sources

Microneedles in Drug Delivery: Progress and Challenges

Micromachines, 2021
In recent years, an innovative transdermal delivery technology has attracted great interest for its ability to distribute therapeutics and cosmeceuticals for several applications, including vaccines, drugs, and biomolecules for skin-related problems. The
Muhammet Avcil, Ayhan Çelik
semanticscholar   +1 more source

Porous Coatings by Vapor Sublimation and Deposition for Molecular Channeling and Filtration in an Interstitial Fluid Microfiltration Device

Advanced Healthcare Materials, EarlyView.
A vapor‐based porous coating applied within nitinol tubes demonstrated complete suppression of cellular and tissue ingrowth, overcoming a major limitation of implantable interstitial fluid collection devices. Molecular channeling and diffusion are analyzed with probe molecules, showing reliable transport in vitro and in vivo. The coating also achieved >
Yu‐Ming Chang, Chi‐Yu Huang, Yi‐Jia Ke, Yi‐Wei Lin, Yen‐Hui Chan, Ying‐Chang Lu, Yu‐Chih Chiang, Chen‐Chi Wu, Hsien‐Yeh Chen   +8 more
wiley   +1 more source

3D-printed microneedles in biomedical applications

iScience, 2021
Summary: Conventional needle technologies can be advanced with emerging nano- and micro-fabrication methods to fabricate microneedles. Nano-/micro-fabricated microneedles seek to mitigate penetration pain and tissue damage, as well as providing ...
Sajjad Rahmani Dabbagh, Misagh Rezapour Sarabi, Reza Rahbarghazi, Emel Sokullu, Ali K. Yetisen, Savas Tasoglu   +5 more
doaj   +1 more source