Results 111 to 120 of about 33,747 (400)
Rolling Ultrasharp Microneedle Spheres Enable Topical Delivery of Biologics Through the Skin
Advanced Healthcare Materials, EarlyView.Rolling ultraminiaturized microneedle spheres (RUMS), created via two‐photon polymerization, unlock effective and painless topical delivery of messenger RNA (mRNA) and drugs through the skin. By gently forming thousands of microscopic pores, RUMS boost skin permeability by up to 100‐fold.
Theocharis Nikiforos Iordanidis +6 more
wiley +1 more source
Nanosuspension-Based Dissolving Microneedle Arrays for Intradermal Delivery of Curcumin
Pharmaceutics, 2019 The objective of this study was to evaluate the intradermal delivery of curcumin utilising poly(vinylalcohol) (PVA)-based microneedles loaded with curcumin nanosuspension (CU-NS).
Sharif Abdelghany +5 more
doaj +1 more source
Polymer substrates with microneedles for epidermis injection [PDF]
, 2009 Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 2009.Cataloged from PDF version of thesis.Includes bibliographical references (p.
Pavlish, John R
core
Inkjet printing of insulin microneedles for transdermal delivery [PDF]
, 2015 Inkjet printing technology was used to apply insulin polymeric layers on metal microneedles for transdermal delivery. A range of various polymers such as gelatin (GLN), polyvinyl caprolactame-polyvinyl acetate-polyethylene glycol (SOL), poly(2-ethyl-2 ...
Douroumis, Dennis +4 more
core +1 more source
Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs
Advanced Healthcare Materials, EarlyView.This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani +4 more
wiley +1 more source
GelsMicroneedles are of great interest in diverse fields, including cosmetics, drug delivery systems, chromatography, and biological sensing for disease diagnosis.
Rio Yamagishi +7 more
doaj +1 more source
Pharmaceutics, 2020 In the current study, diethylene glycol monoethyl ether-mediated microemulsions were combined with microneedles for enhanced transdermal aconitine delivery.
Yongtai Zhang +6 more
doaj +1 more source
Single-Step Fabrication of Computationally Designed Microneedles by Continuous Liquid Interface Production. [PDF]
PLoS ONE, 2016 Microneedles, arrays of micron-sized needles that painlessly puncture the skin, enable transdermal delivery of medications that are difficult to deliver using more traditional routes.
Ashley R Johnson +9 more
doaj +1 more source
Formulation of hydrophobic peptides for skin delivery via coated microneedles [PDF]
, 2017 Microneedles (MNs) have been investigated as a minimally-invasive delivery technology for a range of active pharmaceutical ingredients (APIs). Various formulations and methods for coating the surface of MNs with therapeutics have been proposed and ...
Birchall, James C. +5 more
core +2 more sources
Advanced Nanoparticle Therapeutics for Targeting Neutrophils in Inflammatory Diseases
Advanced Healthcare Materials, EarlyView.This review highlights recent advances in nanoparticle‐based strategies to modulate neutrophil activity in inflammatory diseases. By targeting inflammatory neutrophils, NET formation, and neutrophil apoptosis or recruitment, these approaches aim to improve therapeutic precision.
Min Ji Byun +9 more
wiley +1 more source