Results 141 to 150 of about 37,259 (377)

A Novel Integrated Transdermal Drug Delivery System with Micropump and Microneedle Made from Polymers [PDF]

, 2022
Ajay Prabhakar Attiguppe, Dhiman Chatterjee, Amitava DasGupta   +2 more
openalex   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Nano-Layered Microneedles for Transcutaneous Delivery of Polymer Nanoparticles and Plasmid DNA [PDF]

, 2010
Multilayer-coated microneedles achieve transcutaneous delivery of plasmid DNA to the viable epidermis. Cy3-labeled plasmid DNA encoding luciferase (yellow) is deposited on biodegradable microneedle arrays through multilayer self-assembly and then ...
Abramoff, Akinc, Bershteyn, Boes, Boudou, Cavalieri, Dimitrova, Donatus, Gill, Gill, Giudice, Glenn, Greenland, Haq, Jessel, Jewell, Jewell, Kim, Kim, Kim, Krogman, Liang, Lynn, Lynn, Mikszta, Park, Pearton, Prausnitz, Prausnitz, Pruss-Ustun, Quan, Su, Wood, Zhang   +33 more
core   +1 more source

Spider Silk–Integrated Biomimetic Micropillars With Dual Adhesion for Improved Wound Hemostasis and Healing

Advanced Materials Technologies, EarlyView.
The patch mimics the dual physicochemical adhesion mechanisms of gecko toe micropillars and spider silk proteins, enabling strong interfacial bonding via partially cured micropillars. Its facile fabrication allows customization for precision medicine, while its motion responsiveness offers potential for real‐time wound monitoring.
Chengxin Luan, Meng Wei, Xinran Chen, Ni Gan, Bingbing Gao   +4 more
wiley   +1 more source

Accelerating topical anaesthesia using microneedles [PDF]

, 2017
Background/Aims: Topical anaesthetics reduce pain during venous access procedures in children. However, clinical use is hindered by a significant anaesthetic onset time.
Birchall, James, Coulman, Sion, Davies, Lleucu, Gateley, Christopher, Holland, Phillip   +4 more
core   +2 more sources

Hollow silicon microneedles, fabricated using combined wet and dry etching techniques, for transdermal delivery and diagnostics

, 2023
Conor O’Mahony, Ryan Sebastian, Fjodors Tjulkins, Derek Whelan, Andrea Bocchino, Yuan Hu, J. O'Brien, Jim Scully, Margaret Hegarty, Alan Blake, Inès Slimi, A. James P. Clover, A.M. Lyness, Anne-Marie Kelleher   +13 more
openalex   +1 more source

Flexible, Integrated‐Porous Microneedle Sensor for Biofluid Sampling and On‐Site Biomarker Detection

Advanced Materials Technologies, EarlyView.
A paper‐integrated porous PGA microneedle array patch capable of both high strength and absorption capacity is proposed. With an image‐processing system, an optimized colorimetric sensor achieves a low limit of detection of 0.09 mm in cholesterol.
Haitao Deng, Heyi Jing, Jongho Park, Beomjoon Kim   +3 more
wiley   +1 more source

Vaccine delivery with microneedle skin patches in nonhuman primates [PDF]

, 2013
Transcutaneous drug delivery from planar skin patches is effective for small-molecule drugs and skin-permeable vaccine adjuvants. However, to achieve efficient delivery of vaccines and other macromolecular therapeutics into the skin, penetration of the ...
Adrienne V Li, Andrew D Miller, B Godin, C Morgan, Christy L Lavine, CJ Martin, Dan H Barouch, Darrell J Irvine, DH Barouch, DJ Shedlock, GM Glenn, Heikyung Suh, HJ Choi, Hualin Li, J Langhorne, Jamal Elkhader, Jinyan Liu, Joshua A Kramer, Kaitlin M Smith, Kelly A Stanley, Michael S Seaman, Paula T Hammond, PC DeMuth, PE Laurent, Peter Abbink, Peter C DeMuth, R Alcock, Wuhbet Abraham, YC Kim   +28 more
core   +3 more sources

May Biodegradable and Biocompatible Polymeric Microneedles be Considered as a Vaccine and Drug Delivery System in the COVID-19 Pandemic? [PDF]

, 2021
Sedat Ünal, Osman Doğan, Yeşim Aktaş
openalex   +1 more source

Programmable Dimensional Lithography with Digital Micromirror Devices for Multifunctional Microarchitectures

Advanced Materials Technologies, EarlyView.
This review explores recent advances in digital micromirror device (DMD)‐based lithography, focusing on its programmable light modulation, multi‐material compatibility, and dimensional patterning strategies. It highlights innovations from optical system design to materials integration and multifunctional applications, positioning DMD lithography as a ...
Yubin Lee, Byungcheon Yoo, Chaeyeong Ryu, Jongwon Oh, Dahye Baek, Jiseok Lee   +5 more
wiley   +1 more source