Results 151 to 160 of about 33,747 (400)

Beyond antigens and adjuvants: formulating future vaccines [PDF]

, 2016
The need to optimize vaccine potency while minimizing toxicity in healthy recipients has motivated studies of the formulation of vaccines to control how, when, and where antigens and adjuvants encounter immune cells and other cells/tissues following ...
Ali, Andrew C. Zmolek, Benson, Boato, Darrell J. Irvine, Desch, Dhodapkar, Dupuis, Garaude, Hanson, Kool, Li, Malyala, Mancini, Pulendran, Ross, Tyson J. Moyer   +16 more
core   +1 more source

Computational and Experimental Analysis of Drug‐Coated Microneedle Skin Insertion: The Mode of Administration Matters

Advanced Materials Interfaces, EarlyView.
This study investigates how the mode of application affects drug delivery from coated microneedles. Combining finite element modeling with custom 3D‐printed Franz Diffusion Cells, the researchers found that prolonged application pressure from microneedles in situ reduces drug permeation.
Wenting Shu, Thomas Lijnse, Fiona McCartney, David J. Brayden, Aisling Ní Annaidh, Eoin D. O'Cearbhaill   +5 more
wiley   +1 more source

3D-printed microneedles in biomedical applications

iScience, 2021
Summary: Conventional needle technologies can be advanced with emerging nano- and micro-fabrication methods to fabricate microneedles. Nano-/micro-fabricated microneedles seek to mitigate penetration pain and tissue damage, as well as providing ...
Sajjad Rahmani Dabbagh, Misagh Rezapour Sarabi, Reza Rahbarghazi, Emel Sokullu, Ali K. Yetisen, Savas Tasoglu   +5 more
doaj  

Silicon micromachined hollow microneedles for transdermal liquid transport [PDF]

, 2003
Han Gardeniers, Regina Lüttge, Erwin Berenschot, Meint J. de Boer, S.Y. Yeshurun, M. Hefetz, Ronny van't Oever, Albert van den Berg   +7 more
openalex   +1 more source

Influenza nucleoprotein DNA vaccination by a skin targeted, dry coated, densely packed microprojection array (Nanopatch) induces potent antibody and CD8+ T cell responses [PDF]

, 2016
DNA vaccines have many advantages such as thermostability and the ease and rapidity of manufacture; for example, in an influenza pandemic situation where rapid production of vaccine is essential.
Fernando, Germain J. P., Haigh, Oscar L., Kendall, Mark A. F., Ng, Hwee-Ing, Yukiko, Sally R., Zhang, Jin   +5 more
core   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Highly Efficient n‐Type Doped Single‐Crystalline Perylene Diimide Microwires via Solution Processing for High‐Performance Photosensors and Photo‐Neuromorphic Devices

Advanced Materials Technologies, EarlyView.
Solution‐processed high‐performance n‐type doped single‐crystalline organic semiconductor microwires (MWs) are reported. n‐Type dopants are located at the terrace edge of the MW, resulting in rapid doping and high interaction. n‐doped MWs show 5,000 times enhanced photosensitivity than evaporated films and high photo‐neuromorphic characteristics by ...
Yonghee Kim, Hye Won Lee, Min Ju Jung, Sangwook Lee, Joon Hak Oh, Eun Kwang Lee   +5 more
wiley   +1 more source

Coated microneedles for transdermal delivery [PDF]

, 2006
Harvinder Singh Gill, Mark R. Prausnitz
openalex   +1 more source

Clinical Challenges in Soft Robotics

Advanced Robotics Research, EarlyView.
This review explores the exciting field of soft robots for medical applications. It delves into the critical challenges facing their development, including material selection, cytotoxicity, and locomotion limitations. The review then examines promising avenues for overcoming these hurdles and achieving clinical translation.
Kailas Mahipal Malappuram, Kaushik Chatterjee, Shervanthi Homer‐Vanniasinkam, Amit Nain   +3 more
wiley   +1 more source

Microneedles for advanced ocular drug delivery.

Advanced Drug Delivery Reviews, 2023
Katie Glover, Deepakkumar Mishra, Shilpkala Gade, Lalitkumar K, Vora, Yu Wu, A. Paredes, Ryan F. Donnelly, Thakur Raghu Raj Singh   +8 more
semanticscholar   +1 more source