Results 1 to 10 of about 6,495 (271)

Microneedling-assisted delivery of metformin versus tranexamic acid in treating melasma: a randomized controlled study. [PDF]

Eur J Med Res
Melasma is a common, relapsing hyperpigmentation disorder with limited long-term treatment success. Recent advances suggest that microneedling may enhance the transdermal delivery and efficacy of topical agents.
Al Mohammady A, Kadah AS, Mahran MA, Elsaie ML.   +3 more
europepmc   +5 more sources

A Split Face Study to Compare the Efficacy of Platelet-Rich Plasma Combined with Microneedling Versus Microneedling Alone for Treatment of Acne Scars. [PDF]

Indian Dermatol Online J
Background: Microneedling is one of the cost-efficient and safe procedures for treatment of atrophic scars. Previous studies have shown variable results regarding the increased efficacy of platelet-rich plasma (PRP) when combined with microneedling ...
Damodaran J, Mohanan S, Mathiyalgen P, Carounanidhy U.   +3 more
europepmc   +4 more sources

Transepidermal Delivery of Calcium Hydroxyapatite (CaHA) Microneedling: A Novel Approach for Inducing Collagen Types III and IV. [PDF]

Biomedicines
Background/Objectives: Microneedling is increasingly applied to enhance transepidermal drug delivery. Calcium hydroxyapatite (CaHA) has recognized biostimulatory properties, but its delivery and distribution within the dermis remain poorly characterized.
Costa ALO, Barcellos FVC, Mariano MTS, Santos EM, Queiroz LDRP, Santos EP, de Melo VRO, Santos SHS, Farias LC, de Paula AMB, Guimarães ALS.   +10 more
europepmc   +4 more sources

Phase I Clinical Trial: Evaluating the Efficacy, Safety, and Patient Satisfaction of Platelet-Rich Plasma (PRP) Injections and Microneedling for Androgenetic Alopecia Treatment. [PDF]

J Cosmet Dermatol
Platelet‐rich plasma (PRP) has been widely utilized in dermatological treatments, leading to the development of various administration methods. This study aims to evaluate and compare the effectiveness of PRP injections and microneedling techniques for ...
Nilforoushzadeh MA, Roohaninasab M, Behrangi E, Jafarzadeh A, Nouri M, Zare S, Zare S.   +6 more
europepmc   +4 more sources

To Evaluate the Efficacy of Ozonated Olive Oil with Microneedling for Gingival Inflammation-A Clinical Study.

J Pharm Bioallied Sci
Background: Scaling and root planing (SRP) remains the gold standard for managing gingival and periodontal diseases. However, adjunctive therapies like ozone and microneedling have emerged as potential methods for enhancing clinical outcomes.
Duble A, Bagde H, Boddun M, Lohiya K, Rathi R, Riza N.   +5 more
europepmc   +4 more sources

Investigating the potential mechanism of microneedling in alopecia areata mice based on 16S rRNA sequencing and metabolomics. [PDF]

Front Microbiol
Background The present study investigates the relationship between alopecia areata (AA) and intestinal microecology, examining the effect of microneedling on the microecology of alopecia areata.
Zhang Y, Li L, Cao L, Xia R.
europepmc   +4 more sources

Preliminary Histological Evidence of Epidermal and DEJ Remodeling with Microneedling-Assisted Topical Exosome Therapy: A Single-Subject Case Report. [PDF]

Clin Cosmet Investig Dermatol
Purpose This study aimed to evaluate the histological effects of microneedling-assisted topical exosome therapy on the dermoepidermal junction (DEJ) and surrounding epidermal structures in aging skin.
Lee YS.
europepmc   +4 more sources

Efficacy of the Combination Therapy of Intense Pulsed Light and Microneedling With a Postbiotic Formulation for Melasma. [PDF]

J Cosmet Dermatol
Melasma pathogenesis involves multifactorial mechanisms, and a comprehensive strategy achieves superior outcomes compared to monotherapy. Intense pulsed light (IPL) reduces pigmentation via selective photothermal effects, while microneedling enhances ...
Li Z, Xiang Y, Meng J, Wang H, Wu H, Li T, Jiang X, Wu T, Zhang Y, Xiao X, Ma X, Yang M, Zhu H, Bi Y, Chen Y, Lei H, Hu J, Huang G, Cong L, Wang J, Yan L, Zhou H, Li C, Zhang X, Ou M, Meng Q.   +25 more
europepmc   +2 more sources

Microneedling for Non-cosmetic Dermatologic Conditions: A Systematic Review of Efficacy and Safety. [PDF]

Cureus
Microneedling, a minimally invasive dermatologic procedure, has expanded beyond cosmetic use to treat conditions such as vitiligo, hyperhidrosis, melasma, acne vulgaris, and actinic keratoses.
Mashi A, Oraybi RA, Hakami MS, Altalhi AM, Alrezqi WA, Hakami TK, Masmali AM, Alshahrani AF, Alamri RA, Alanazi AA.   +9 more
europepmc   +2 more sources

A Comparative Study of the Efficacy of Chemical Peels and Microneedling in the Treatment of Moderate to Severe Melasma. [PDF]

Cureus
Background: Melasma is a chronic, relapsing hyperpigmentation disorder that commonly affects individuals with darker skin phototypes, leading to significant cosmetic and psychological distress.
Batool A, Seger AJ, Akhtar N, Mateen S, Amiruddin MU, Zain M.   +5 more
europepmc   +2 more sources