Results 21 to 30 of about 196,913 (332)

Micronization of a poorly water-soluble drug, fenofibrate, via supercritical-fluid-assisted spray-drying

Journal of Pharmaceutical Investigation, 2022
In the present study, fenofibrate (a model drug with poor aqueous solubility) was micronized using the supercritical-fluid-assisted spray-drying (SA-SD) process to improve dissolution and biopharmaceutical property.
Jeong-Soo Kim, Heejun Park, K. Kang, Eun-Sol Ha, Min-Soo Kim, Sung-Joo Hwang   +5 more
semanticscholar   +1 more source

Hesperidin Bioavailability Is Increased by the Presence of 2S-Diastereoisomer and Micronization—A Randomized, Crossover and Double-Blind Clinical Trial

Nutrients, 2022
Hesperidin is a flavanone abundantly found in citrus fruits for which health beneficial effects have been reported. However, hesperidin shows a low bioavailability among individuals.
A. Crescenti, A. Caimari, J. M. Alcaide-Hidalgo, Roger Mariné-Casadó, R. Valls, J. Companys, P. Salamanca, L. Calderón-Pérez, L. Pla-Pagà, A. Pedret, A. Delpino-Rius, P. Herrero, I. Samarra, L. Arola, R. Solà, J. D. del Bas   +15 more
semanticscholar   +1 more source

Curcumin micronization by supercritical fluid: in vitro and in vivo biological relevance

bioRxiv, 2021
Curcumin, a polyphenol extracted from the rhizome of Curcuma longa L. (Zingiberaceae), is shown to have antioxidant, anti-inflammatory, neuroprotective, anxiolytic, and antidepressant properties in both preclinical and clinical studies.
A. Sachett, Matheus Gallas-Lopes, R. Benvenutti, M. Marcon, G. P. Aguiar, A. Herrmann, J. Oliveira, A. Siebel, A. Piato   +8 more
semanticscholar   +1 more source

The Role of Hidden Conformers in Determination of Conformational Preferences of Mefenamic Acid by NOESY Spectroscopy

Pharmaceutics, 2022
Mefenamic acid has been used as a non-steroidal anti-inflammatory drug for a long time. However, its practical use is quite limited due to a number of side effects on the intestinal organs.
Konstantin V. Belov, Luís A. E. Batista de Carvalho, Alexey A. Dyshin, Sergey V. Efimov, Ilya A. Khodov   +4 more
doaj   +1 more source

Micronization Techniques for Solubility Enhancement of Aceclofenac as a potential Solubility Enhancement Approach [PDF]

, 2023
Aceclofenac is a BCS class II poorly aqueous soluble drug that has significant oral bioavailability limitations after intake. Numerous solubility enhancement techniques are available for the solubility enhancement, out of various techniques Micronization
Vishal Gupta, Sokindra Kumar, Rajesh Agrawal   +2 more
core   +1 more source

Chronic Pain in Dogs and Cats: Is There Place for Dietary Intervention with Micro-Palmitoylethanolamide?

Animals, 2021
The management of chronic pain is an integral challenge of small animal veterinary practitioners. Multiple pharmacological agents are usually employed to treat maladaptive pain including opiates, non-steroidal anti-inflammatory drugs, anticonvulsants ...
Giorgia della Rocca, Davide Gamba
doaj   +1 more source

Effect of micronization of maize grains on shelf-life of flour

, 2017
The efficacy of micronization of maize (Arjun, EH-434042) in inactivating enzymes responsible for lipid degradation and extending the shelf-life of whole maize flour was evaluated.
C. Deepa, H. U. Hebbar
semanticscholar   +2 more sources

Micronization increases the bioaccessibility of polyphenols from granulometrically separated olive pomace fractions.

Food Chemistry, 2020
The effect of micronization of granulometrically fractionated olive pomace (OP) on the bioaccessibility of polyphenols and the antioxidant capacity was investigated during sequential in vitro static digestion.
Caroline Sefrin Speroni, Daniela Rigo Guerra, Ana Betine Beutinger Bender, Jéssica Stiebe, C. A. Ballus, Leila Picolli da Silva, J. Lozano-Sánchez, T. Emanuelli   +7 more
semanticscholar   +1 more source

Decellularized Articular Cartilage Microgels as Microcarriers for Expansion of Mesenchymal Stem Cells

Gels, 2022
Conventional microcarriers used for expansion of human mesenchymal stem cells (hMSCs) require detachment and separation of the cells from the carrier prior to use in clinical applications for regeneration of articular cartilage, and the carrier can cause
Esmaiel Jabbari, Azadeh Sepahvandi, Safaa Ibrahim Kader, Victor Anthony Madormo   +3 more
doaj   +1 more source

Granulometric fractionation and micronization: A process for increasing soluble dietary fiber content and improving technological and functional properties of olive pomace

, 2020
The aim of this study was to evaluate the effect of micronization of granulometrically separated olive pomace fractions on dietary fiber composition, technological and functional properties.
C. Speroni, A. B. B. Bender, Jéssica Stiebe, C. A. Ballus, P. F. Ávila, Rosana Goldbeck, Fernando Dal Pont Morisso, L. P. da Silva, T. Emanuelli   +8 more
semanticscholar   +1 more source