Results 131 to 140 of about 48,051 (246)

Untreated Hair Dye Effluents Enter the Environment: Are They a Threat to Human Health?

Environmental Toxicology, Volume 41, Issue 10, Page 998-1010, October 2026.
ABSTRACT The effluents generated during the process of hair dyeing exhibit a complex composition, comprising chemical compounds with varying toxicity levels. While the adverse impact of hair dyes on human health is acknowledged, there is a notable absence of studies addressing the toxicity associated with effluents produced during these activities. The
Letícia Cristina Gonçalves, Matheus Mantuanelli Roberto, Adriana Fabiana Corrêa da Silva, Maria Aparecida Marin‐Morales   +3 more
wiley   +1 more source

Avaliação toxicológica em peixes da espécie Oreochromis niloticus expostos às águas do Rio Cubatão do Sul/SC: estudo genotóxico, epigenético e de estresse oxidativo [PDF]

, 2013
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Ambiental, Florianópolis, 2013.A poluição aquática é considerada uma das principais preocupações ambientais nas áreas urbanas.
Fuzinatto, Cristiane Funghetto
core  

Splicing Factor Mutations in Clonal Hematopoiesis and Progression to Myeloid Neoplasms

Cancer Science, Volume 117, Issue 10, Page 2609-2618, October 2026.
Splicing factor (SF)‐mutant CH is characterized by relatively late emergence and accelerated clonal expansion in older individuals. This review summarizes its clonal dynamics, disease‐associated consequences of SF mutations in myeloid neoplasms, and candidate mechanisms that may contribute to age‐dependent selection.
Yang Lyu, Yutong Zhang, Ayana Kon
wiley   +1 more source

The automated micronucleus assay for early assessment of genotoxicity in drug discovery

, 2013
International audienceRecent publications on the automated in vitro micronucleus assay show predictive values higher than 85% for the classification of in vitro aneugens, clastogens and non-genotoxic compounds.
Gerets, H.H.J., De Ron, P., Atienzar, F.A., Tilmant, K., Vasseur, P., Cossu-Leguille, C., Dhalluin, S.   +6 more
core   +1 more source

Sewage sludge does not induce genotoxicity and carcinogenesis

Genetics and Molecular Biology, 2012
Through a series of experiments, the genotoxic/mutagenic and carcinogenic potential of sewage sludge was assessed. Male Wistar rats were randomly assigned to four groups: Group 1 - negative control; Group 2 - liver carcinogenesis initiated by ...
Paula Regina Pereira Silva, Luis Fernando Barbisan, Maria Lúcia Zaidan Dagli, Paulo Hilário Nascimento Saldiva   +3 more
doaj  

Modification of the existing maximum residue levels for propyzamide in oilseeds and honey

EFSA Journal, Volume 24, Issue 10, October 2026.
Abstract In accordance with Article 6 of Regulation (EC) No 396/2005, the applicant Corteva submitted a request to the competent national authority in Sweden to modify the existing maximum residue levels (MRLs) for the active substance propyzamide in oilseed rape, mustard seeds, gold of pleasure seeds, linseeds, sesame seeds, hemp seeds, borage seeds ...
European Food Safety Authority (EFSA), Sofia Batista Leite, Giulia Bellisai, Giovanni Bernasconi, Marco Binaglia, Irene Castellan, Anna Federica Castoldi, Arianna Chiusolo, Mathilde Colas, Federica Crivellente, Monica Del Aguila, Lucien Ferreira, Frederique Istace, Anna Lanzoni, Renata Leuschner, Jochem Louisse, Iris Mangas, Silvia Mazzega, Andrea Mioč, Martina Panzarea, Juan Manuel Parra Morte, Simone Rizzuto, Marta Szot, Manuela Tiramani, Alessia Verani   +24 more
wiley   +1 more source

The buccal micronucleus cytome assay: New horizons for its implementation in human studies

In this report we provide a summary of the presentations and discussion of the latest knowledge regarding the buccal micronucleus (MN) cytome assay. This information was presented at the HUMN workshop held in Malaga, Spain, in connection with the 2023 ...
Schunck, C., Volpi, E., Bonassi, S., Wultsch, G., Knasmueller, S., Nersesyan, A., Fenech, M., Bolognesi, C.   +7 more
core   +1 more source

Safety evaluation of the food enzyme cellulase from the genetically modified Trichoderma reesei strain NZYM‐FS

EFSA Journal, Volume 24, Issue 10, October 2026.
Abstract The food enzyme cellulase (4‐(1,3; 1,4)‐β‐d‐glucan‐4‐glucanohydrolase, EC 3.2.1.4) is produced with the genetically modified Trichoderma reesei strain NZYM‐FS by Novozymes A/S. The genetic modifications did not give rise to safety concerns. The food enzyme was considered free from viable cells of the production organism and its DNA.
EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Henk Van Loveren, Laurence Vernis, Cristina Andreoli, Andrea Terron, Andrey Yurkov, Ana Gomes, Daniele Cavanna, Cristina Fernández‐Fraguas, Natália Kovalkovičová, Yi Liu   +20 more
wiley   +1 more source

Estudo da frequência de hemócitos micronucleados, induzidos pelo ácido ocadáico, em mexilhões Perna perna (Mollusca : Bivalvia) / [PDF]

, 2000
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico.Algumas toxinas presentes naturalmente no ambiente marinho são capazes de induzir mutagenicidade e/ou carcinogenicidade.
Silva, Cátia Regina
core  

Micronucleus frequency after different exposure conditions.

, 2013
Columns represent means and error bars represent standard deviations of at least three independent experiments (2×1,000 cells per replicate). Untreated controls (C) and positive controls (MMC and VIN) are presented as historical controls performed at ...
Christian Jastrow (305547), Thorsten Schrader (305550), Helga Stopper (74364), Thomas Kleine-Ostmann (305548), Uwe Kärst (61278), Henning Hintzsche (297302)   +5 more
core   +1 more source