The micronucleus test-most widely used in vivo genotoxicity test. [PDF]
Genes Environ, 2016 Genotoxicity is commonly evaluated during the chemical safety assessment together with other toxicological endpoints. The micronucleus test is always included in many genotoxic test guidelines for long time in many classes of chemicals, e.g., pharmaceutical chemicals, agricultural chemicals, food additives.
Hayashi M.
europepmc +5 more sources
Micronucleus test using formalin-fixed rat glandular stomach and colon [PDF]
Genes and Environment, 2023 Background Genotoxicity in tissues other than hematopoietic tissues, such as the liver and gastrointestinal (GI) tract, is an important focus in the risk assessment of chemicals in humans. We previously developed a rat micronucleus test for the GI tract,
Wakako Ohyama +4 more
doaj +2 more sources
Vicia–Micronucleus Test Application for Saline Irrigation Water Risk Assessment [PDF]
Plants, 2022 In view of climate change, increasing soil salinity is expected worldwide. It is therefore important to improve prediction ability of plant salinity effects. For this purpose, brackish/saline irrigation water from two areas in central and coastal Tunisia
Dalila Souguir +4 more
doaj +2 more sources
Assessment of the genotoxicity of quinolone and fluoroquinolones contaminated soil with the Vicia faba micronucleus test [PDF]
Ecotoxicology and Environmental Safety, 2012 The genotoxicity of quinolone and fluroquinolones was assessed using the micronucleus (MN) test on Viciafaba roots by direct contact exposure to a solid matrix.
Bousquet-Mélou, Alain +7 more
core +4 more sources
Evaluation of Genotoxicity by Micronucleus Assay in vitro and by Allium cepa Test in vivo
Bio-Protocol, 2019 The in vitro and in vivo genotoxicity of new metallodrugs either as Small Bioactive Molecules (SBAMs) or Conjugates of Metals with Drugs (CoMeDs) is evaluated by the micronucleus test and the Allium cepa assay, respectively.
Christina Banti, Sotiris Hadjikakou
doaj +2 more sources
Oral Acute Toxicity and Genotoxicity of Heteroctenus junceus Scorpion Venom [PDF]
Veterinary Medicine and ScienceObjective The study evaluates the elemental composition, oral acute toxicity, genotoxicity, and mutagenic potential of Heteroctenus junceus scorpion venom.
Alexis Díaz‐García +4 more
doaj +2 more sources
Estimating the carcinogenic potency of chemicals from the in vivo micronucleus test. [PDF]
Mutagenesis, 2016 Soeteman-Hernández LG +2 more
europepmc +2 more sources
Genotoxicity of Di (2-ethyl hexyl) phthalate
Zhongguo shipin weisheng zazhi, 2022 ObjectiveTo assess the genotoxicity of Di（2-ethylhexyl） phthalate （DEHP）.MethodsA series of guideline-compliant assays were performed to evaluate mutagenicity， chromosomal or DNA damage of DEHP， including Ames test， in vitro mammalian chromosome ...
LI Juntao +9 more
doaj +1 more source
In vitro micronucleus assay: Method for assessment of nanomaterials using cytochalasin B
Frontiers in Toxicology, 2023 The in vitro micronucleus (MNvit) assay is used to evaluate the aneugenic and clastogenic potential of a test material based upon its ability to induce micronuclei in the cells.
Christopher S. Farabaugh +3 more
doaj +1 more source
Cytogenetic effect of caffeine in the micronucleus test
RUDN Journal of Medicine, 2021 Relevance. The consumption of caffeine-containing food in the modern world must necessarily be safe for humans, including should not affect the hereditary material of the body.
N. A. Durnova +4 more
doaj +1 more source