Results 1 to 10 of about 12,961 (162)

Salivary ki-67 and micronucleus assay as potential biomarker of OSCC in betel nut chewers

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2021
Introduction: Oral cancer is often associated with various factors, such as betel nut consumption, which usually causes specific premalignant lesions. The most common oral cancer is oral squamous cell carcinoma (OSCC) which has a low 5-year survivor rate
Maulina Triani   +4 more
doaj   +1 more source

Investigation of Toxicity in Black Jaw Tilapia (Sarotherodon melanotheron) Exposed to Crude Oil [PDF]

open access: yesIranica Journal of Energy and Environment, 2020
The toxicity effects of crude oil were investigated in the laboratory. Triplicates of (T1) 0.25mg/l, (T2) 1.0mg/l, (T3) 2.25mg/l, (T4) 5.0mg/l and (T5) 7.5mg/l concentration of crude oil exposed to Sarotherodon melanotheron species.
S. O. Ayoola, C. E. Ejikeme, O. Folami
doaj   +1 more source

Assessment of methyl methacrylate genotoxicity by the micronucleus test

open access: yesBrazilian Oral Research, 2013
The aim of this study was to evaluate the genotoxic potential of methyl methacrylate (MMA) vapor by simulating standard occupational exposure of 8 hours per day and using the micronucleus test. We used 32 adult male Wistar rats divided into three groups:
Amarildo Mariano de Araújo   +4 more
doaj   +1 more source

Mutagenicity and genotoxicity of ClearTaste

open access: yesToxicology Reports, 2018
The present study investigates whether ClearTaste is mutagenic/genotoxic by employing it as a test article in bacterial reverse mutation (Ames test) and in vitro human peripheral blood lymphocyte micronucleus assays conducted by a Good Laboratory ...
B.K. Soni, J.P. Langan
doaj   +1 more source

Mutagenicity test of feed pentacyclic triterpenoid extract

open access: yesSiliao yanjiu, 2023
The purpose of the experiment is to evaluate whether pentacyclic triterpeneds extracts as a feed additive has potential mutagenicity through Ames test, micronucleus test and sperm deformity test.
ZHANG Yuan   +4 more
doaj  

A Double Fluorescent Staining Method Increases the Sensitivity of the Cytokinesis-Block Micronucleus Assay

open access: yesMethods and Protocols
The micronucleus test is one of the most popular genotoxicity assays. In order to avoid underestimation of micronuclei frequencies by counting non-replicating cells, the cytokinesis-blocked micronucleus test has been developed.
Ion Udroiu
doaj   +1 more source

MICRONUCLEUS TEST OF MOFEZOLAC (N-22)

open access: yesThe Journal of Toxicological Sciences, 1990
A micronucleus test using BDF1 male mice was conducted in order to evaluate the in vivo mutagenicity of mofezolac (N-22). N-22 was orally administered at doses of 75, 150, 300 and 600 mg/kg, with a sampling time of 24 hr. The frequency of polychromatic erythrocytes with micronuclei was 0.07-0.08% in the groups treated with N-22 and did not differ ...
OHUCHIDA, Akinobu, FURUKAWA, Akemi
openaire   +3 more sources

CDK4/6 inhibitor-induced bone marrow micronuclei might be caused by cell cycle arrest during erythropoiesis

open access: yesGenes and Environment
Background A micronucleus test is generally used to evaluate the genotoxic potential of chemicals. Exaggerated erythropoiesis, as occurs following bleeding, may induce an unexpected increase in micronucleus frequency.
Yuki Okada   +3 more
doaj   +1 more source

Effect of the GSTM1 genotype on the biomarkers of exposure to polycyclic aromatic hydrocarbons: Meta-analysis

open access: yesInternational Journal of Occupational Medicine and Environmental Health, 2017
The role of glutathione S-transferase Mu 1 (GSTM1) in the biomonitoring of polycyclic aromatic hydrocarbons (PAHs) is not clear. Our purpose has been to evaluate the influence of GSTM1 genotypes on 1-hydroxypyrene (1-OHP), deoxyribonucleic acid (DNA ...
Dandan Li   +5 more
doaj   +1 more source

Evaluation of Genotoxicity by Micronucleus Assay in vitro and by Allium cepa Test in vivo

open access: yesBio-Protocol, 2019
The in vitro and in vivo genotoxicity of new metallodrugs either as Small Bioactive Molecules (SBAMs) or Conjugates of Metals with Drugs (CoMeDs) is evaluated by the micronucleus test and the Allium cepa assay, respectively.
Christina Banti, Sotiris Hadjikakou
doaj   +1 more source

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