Molecules, 2023 This study evaluated the genotoxicity of Ethanol Extract (EEEp), Dichloromethane Fraction (FDCMEp) and isoeleutherin isolated from Eleutherine plicata, using the micronucleus test and the impact of structural alterations on toxicity and molecular docking
Kelly Cristina Oliveira de Albuquerque +9 more
doaj +1 more source
The micronucleus assay as a biological dosimeter of in vivo ionising radiation exposure [PDF]
, 2010 Biological dosimetry, based on the analysis of micronuclei (MN) in the cytokinesis-block micronucleus (CBMN) assay can be used as an alternative method for scoring dicentric chromosomes in the field of radiation protection.
Fenech, Michel +2 more
core +2 more sources
Evaluation of the genotoxic and teratogenic potential of a municipal sludge and sludge-amended soil using the amphibian Xenopus laevis and the tobacco: Nicotiana tabacum L. var. xanthi Dulieu [PDF]
, 2003 The toxic, genotoxic and teratogenicpotential of amunicipal sewage sludge was assessed using the micronucleus assay on the larvae of the amphibianXenopuslaevis and with the tobacco somatic mutation test using the yellow–green xanthiDulieu mutant a1+/a1 ...
Chenon, Pascale +4 more
core +4 more sources
Evaluation of the edible safety of Amaranthus caudatus seeds based on cellular and toxicological experiments [PDF]
Zhongguo niangzaoA toxicological evaluation for edible safety of Amaranthus caudatus seeds was conducted. In the acute oral toxicity test, SPF mice was administered a one-time gavage at a dose of 10 000 mg/kg.
A Ruhan, LU Bingyun, HE Mengchao, ZHONG Heng, HAN Xinglin, LUO Ruiqi, WANG Deliang
doaj +1 more source
New direct contact approach to evaluate soil genotoxicity using the Vicia faba micronucleus test. [PDF]
, 2009 A method to assess micronucleus (MN) induction in Vicia faba roots by direct contact exposure to a solid matrix was developed. The procedure comprised a 5-d germination period, as in the well-known method using aqueous extracts.
Cecchi, Marie +4 more
core +3 more sources
Evaluation of the novel liver micronucleus assay using formalin-fixed tissues
Genes and Environment, 2019 Background The repeated-dose liver micronucleus (RDLMN) assay is an effective and important in vivo test for detecting genotoxic compounds, particularly for those that require metabolic activation to show genotoxicity.
Shuichi Hamada +12 more
doaj +1 more source
Mutagenic impact on fish of runoff events in agricultural areas in south-west France [PDF]
, 2011 When heavy rainfall follows herbicide application, the intense surface runoff causes stream water contamination. Aquatic organisms are then briefly exposed to a complex mixture of contaminants.
Gauthier, Laury +6 more
core +2 more sources
MICRONUCLEUS TEST IN MOST RECENT ICHTHIOLOGY RESEARCH [PDF]
Croatian Journal of Fisheries, 2005 The purpose of this paper was to give an insight into the most recent ichthiology research in which Micronucleus test is used. This test has been used for some time now as a tool for determining DNA damage in model–organism. Scientists have been using it
Vesna Mijat
doaj
Investigation of Toxicity in Black Jaw Tilapia (Sarotherodon melanotheron) Exposed to Crude Oil [PDF]
Iranica Journal of Energy and Environment, 2020 The toxicity effects of crude oil were investigated in the laboratory. Triplicates of (T1) 0.25mg/l, (T2) 1.0mg/l, (T3) 2.25mg/l, (T4) 5.0mg/l and (T5) 7.5mg/l concentration of crude oil exposed to Sarotherodon melanotheron species.
S. O. Ayoola, C. E. Ejikeme, O. Folami
doaj +1 more source
Chronic ethanol consumption in mice does not induce DNA damage in somatic or germ cells, evaluated by the bone marrow micronucleous assay and the dominant lethal mutation assay [PDF]
, 2012 Indexación: Web of Science; ScieloAlthough alcohol is known to be a carcinogen for humans, ethanol-genotoxicity studies are incomplete. Ethanol seems not to be a bacterial mutagen, but the results are conflicting in rodent assays.
Ellahueñe, Manuel +2 more
core +1 more source