Results 51 to 60 of about 15,516,475 (251)

CDK4/6 inhibitor-induced bone marrow micronuclei might be caused by cell cycle arrest during erythropoiesis

Genes and Environment
Background A micronucleus test is generally used to evaluate the genotoxic potential of chemicals. Exaggerated erythropoiesis, as occurs following bleeding, may induce an unexpected increase in micronucleus frequency.
Yuki Okada, Satsuki Chikura, Takafumi Kimoto, Takeshi Iijima   +3 more
doaj   +1 more source

Effect of the GSTM1 genotype on the biomarkers of exposure to polycyclic aromatic hydrocarbons: Meta-analysis

International Journal of Occupational Medicine and Environmental Health, 2017
The role of glutathione S-transferase Mu 1 (GSTM1) in the biomonitoring of polycyclic aromatic hydrocarbons (PAHs) is not clear. Our purpose has been to evaluate the influence of GSTM1 genotypes on 1-hydroxypyrene (1-OHP), deoxyribonucleic acid (DNA ...
Dandan Li, Bingling Wang, Guochang Feng, Meng Xie, Lijuan Wang, Ruqin Gao   +5 more
doaj   +1 more source

Genotoxic mixtures and dissimilar action: Concepts for prediction and assessment [PDF]

, 2013
This article has been made available through the Brunel Open Access Publishing Fund. This article is distributed under the terms of the creative commons Attribution license which permits any use, distribution, and reproduction in any medium, provided ...
A Bouslimi, A Elhajouji, Andreas Kortenkamp, AY Kocaman, CI Bliss, D Kirkland, E Hecker, K Drescher, K Hashimoto, K Hashimoto, M Faust, M Fenech, M Honma, M Marinovich, M Scholze, Martin Scholze, MC Berenbaum, MC Berenbaum, National Research Council, P Fowler, R Altenburger, S Ermler, S Loewe, Sibylle Ermler, T Backhaus, T Mosmann, W Slob, WK Lutz, WK Lutz, WK Lutz   +29 more
core   +2 more sources

Clinical Application of Micronucleus Test: A Case-Control Study on the Prediction of Breast Cancer Risk/Susceptibility

PLoS ONE, 2014
The micronucleus test is a well-established DNA damage assay in human monitoring. The test was proposed as a promising marker of cancer risk/susceptibility mainly on the basis of studies on breast cancer.
C. Bolognesi, P. Bruzzi, V. Gismondi, S. Volpi, V. Viassolo, S. Pedemonte, L. Varesco   +6 more
semanticscholar   +1 more source

Increased micronucleated cell frequency related to exposure to radiation emitted by computer cathode ray tube video display monitors [PDF]

Genetics and Molecular Biology, 2005
It is well recognized that electromagnetic fields can affect the biological functions of living organisms at both cellular and molecular level. The potential damaging effects of electromagnetic fields and very low frequency and extremely low frequency ...
Karina Carbonari, Luciane Gonçalves, Daniela Roth, Patrick Moreira, Ricardo Fernández, Maria da Graça Martino-Roth   +5 more
doaj   +1 more source

The micronucleus assay in radiation accidents [PDF]

, 2009
The cytokinesis-block micronucleus assay in peripheral blood lymphocytes is a standardised and validated technique for biodosimetry. Automated scoring of micronuclei allows large scale applications as in population triage in case of radiation accidents ...
Thierens, Hubert, Vral, Anne
core   +1 more source

Comparison of established and emerging biodosimetry assays [PDF]

, 2013
Rapid biodosimetry tools are required to assist with triage in the case of a large-scale radiation incident. Here, we aimed to determine the dose-assessment accuracy of the well-established dicentric chromosome assay (DCA) and cytokinesis-block ...
Abend, M, Badie, C, Balagurunathan, Y, Barnard, S, Beinke, C, Bernard, N, Boulay-Greene, H, Braselmann, H, Brengues, M, De Amicis, A, De Sanctis, S, Greither, R, Herodin, F, Jones, A, Kabacik, S, Knie, T, Kulka, U, Lista, F, Martigne, P, Meineke, V, Missel, A, Moquet, J, Oestreicher, U, Peinnequin, A, Poyot, T, Roessler, U, Romm, H, Rothkamm, K, Scherthan, H, Terbrueggen, B, Thierens, Hubert, Valente, M, Vral, Anne, Zenhausern, F   +33 more
core   +2 more sources

Biomonitoring of the genotoxic potential of aqueous extracts of soils and bottom ash resulting from municipal solid waste incineration, using the comet and micronucleus tests on amphibian (Xenopus laevis) larvae and bacterial assays (MutatoxR and Ames tests) [PDF]

, 2006
The management of contaminated soils and wastes is a matter of considerable human concern. The present study evaluates the genotoxic potential of aqueous extracts of two soils (leachates) and of bottom ash resulting from municipal solid waste ...
Devaux, Alain, Ferrier, Vincent, Gauthier, Laury, Jourdain, Marie-José, Mailhes, Corinne, Mouchet, Florence, Triffault, Gaëlle   +6 more
core   +2 more sources

Scientific Opinion on Flavouring Group Evaluation 57, Revision 1 (FGE.57Rev1): consideration of isopulegone and three flavouring substances evaluated by JECFA (55th meeting) [PDF]

, 2017
Publisher ...
Anastassiadou, Maria, Bolognesi, Claudia, Brimer, Leon, Carfí, Maria, Castle, Laurence, Cravedi, Jean-Pierre, de Fátima Tavares Poças, Maria, EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF), Engel, Karl-Heinz, Fowler, Paul, Franz, Roland, Grob, Konrad, Gürtler, Rainer, Husøy, Trine, Kärenlampi, Sirpa, Marcon, Francesca, Mennes, Wim, Mulder, Gerard, Penninks, André, Rosaria Milana, Maria, Silano, Vittorio, Smith, Andrew, Sundh, Ulla Beckman, Tlustos, Christina, Wölfle , Detlef, Zorn, Holger, Zugravu, Corina-Aurelia   +26 more
core   +3 more sources

Toxicology evaluation of selenium protein powder

BIO Web of Conferences, 2017
The experiment was conducted to evaluate the safety of selenium protein powder, a novel organic selenium nutritional supplement, and reported corresponding data and results based on a series of toxicological tests.
Qin Shunyi, Liu Lina, Wang Jingshen, Zhao Fanghong, Ma Jifei   +4 more
doaj   +1 more source