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Integrating Adaptive Responses Into Hormesis: δ Plot Analysis of the Yonezawa Effect in the Micronucleus Test [PDF]
Dose-ResponseObjectives Cells and organisms respond dynamically to environmental stimuli such as radiation and chemicals. Depending on the assay system, these responses have been described as hormesis, adaptive responses, J-shaped responses, and biphasic responses ...
Shizuyo Sutou +5 more
doaj +2 more sources
Genotoxicity Assessment of Multispecies Probiotics Using Reverse Mutation, Mammalian Chromosomal Aberration, and Rodent Micronucleus Tests [PDF]
The Scientific World Journal, 2013 Genotoxicity assessment is carried out on freeze dried powder of cultured probiotics containing Lactobacillus rhamnosus LCR177, Bifidobacterium adolescentis BA286, and Pediococcus acidilactici PA318.
Yi-Jen Chiu +4 more
doaj +2 more sources
Is duration of exposure a determinant factor for genotoxicity and clinical manifestations induced by Formaldehyde? [PDF]
Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 2021 Introduction: Formaldehyde is a naturally occurring compound extensively used as cadavers' preservative in medical schools anatomy departments. The International Agency for Research on Cancer (IARC) classifies formaldehyde as carcinogenic to humans ...
Elsayed Metwally +4 more
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Evaluation of genome stability of bone marrow cells of dogs with naturally infected visceral leishmaniasis [PDF]
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2023 The aim of this article is to identify and evaluate the genomic stability of visceral leishmaniasis in naturally infected dogs. A total of 32 dogs participated in the study, 24 of which were asymptomatic animals, naturally infected, and 8 uninfected ...
P.M.P. Silva +4 more
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Genotoxicity of Di (2-ethyl hexyl) phthalate
Zhongguo shipin weisheng zazhi, 2022 ObjectiveTo assess the genotoxicity of Di（2-ethylhexyl） phthalate （DEHP）.MethodsA series of guideline-compliant assays were performed to evaluate mutagenicity， chromosomal or DNA damage of DEHP， including Ames test， in vitro mammalian chromosome ...
LI Juntao +9 more
doaj +1 more source
Brazilian Oral Research, 2023 The aim of this systematic review was to evaluate published papers regarding the micronucleus assay in oral mucosal cells of patients undergoing orthodontic therapy (OT).
Daniel Vitor de SOUZA +5 more
doaj +1 more source
Assessment of the Genotoxic and Cytotoxic Effects of Turpentine in Painters
Life, 2023 Turpentine is a fluid used mainly as a solvent for thinning oil-based paints, obtained by distilling the resin of coniferous trees. Fine art painters use turpentine on a daily basis.
Sara Kević Dešić +2 more
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The Turkish Journal of Pediatrics, 2023 Background. Every year, thousands of donors are exposed to granulocyte-colony stimulating factor (G-CSF) for stem cell mobilization in hematopoietic stem cell transplantations (HSCT).
Hasan Fatih Çakmaklı +5 more
doaj +1 more source
The Micronucleus Test for Occupational Safety. [PDF]
Med LavAlthough less commonly used than internal dose indicators, biological effect indicators can be valuable for Risk Assessment. Among the numerous biomarkers used to date, those that indicate DNA damage could be especially useful for occupational safety, as they predict the risk of carcinogenesis.
Udroiu I, Giliberti C, Sgura A.
europepmc +3 more sources
Micronucleus level in exfoliated buccal mucosa cells of cancer patients [PDF]
Archive of Oncology, 2002 Micronucleus levels in exfoliated buccal mucosa cells of patients with primary breast, lung, cervix uteri cancer, and patients with Hodgkin's disease were studied (n=59).
Nersesyan Armen K. +3 more
doaj +1 more source