Results 1 to 10 of about 7,950 (195)

In vitro cytotoxic and genotoxic effects of newly synthesised boron ionic liquids

Biotechnology & Biotechnological Equipment, 2019
In this study, new molecules containing boron were added to the family of ionic organic compounds, in particular, ionic liquids with a cationic center. This study aimed to determine the cytotoxic and genetic effects of a total of four newly synthesised ...
Sibel Bayil Oguzkan, Hasan Turkez, Bora Karagul, Umit Cakir, Halil Ibrahim Ugras   +4 more
doaj   +1 more source

Detection of Biochemical, Cytotoxic, and Genotoxic Damage Caused by Glufosinate-Ammonium on the Zebrafish Cell Line

Cumhuriyet Science Journal
Pesticides widely used in agriculture can enter aquatic ecosystems and threaten non-target organisms in the environment. In this study, sublethal toxic effects of glufosinate-ammonium on Zebrafish (Danio rerio) liver fibroblast cell line (ZFL) were ...
Harika Eylül Esmer Duruel, Figen Esin Kayhan   +1 more
doaj   +1 more source

Mutagenic effects of tributyltin and inorganic lead (Pb II) on the fish H. malabaricus as evaluated using the comet assay and the piscine micronucleus and chromosome aberration tests

Genetics and Molecular Biology, 2004
Genotoxicity studies on toxic metals and their organic compounds are very important, especially so in the investigation of the effects of these compounds on the aquatic environments where they tend to accumulate.
Marcos Vinícius M. Ferraro, Alberto Sérgio Fenocchio, Mario Sérgio Mantovani, Ciro de Oliveira Ribeiro, Marta Margarete Cestari   +4 more
doaj   +1 more source

Genotoxicity study of an experimental beverage made with quinua, kiwicha and kañiwa

Revista Peruana de Biología, 2014
Genotoxic evaluation is an important step for a product that is aimed for human consumption. A beverage composed of pseudocereals with highly nutritious elements like quinua (Chenopodium quinoa Willd.), kiwicha (Amaranthus caudatus L.) and kañiwa ...
Francia D.P. Huaman, Emily M. Toscano, Oscar Acosta, Diana E. Rojas, Miguel A. Inocente, Diana P. Garrido, María L. Guevara-Fujita   +6 more
doaj   +1 more source

An investigation of the genotoxic potential of a well-characterized yerba mate extract

Toxicology Reports
Yerba Mate (Ilex paraguariensis) is historically used as a beverage and its extracts are considered traditional medicine in South America. Extract use has been expanding to North American and European markets and the currently available genetic ...
C. Doepker, C. Rabert, P. Heard, T. Dubnicka, N. Choksi, A. Eapen   +5 more
doaj   +1 more source

CDK4/6 inhibitor-induced bone marrow micronuclei might be caused by cell cycle arrest during erythropoiesis

Genes and Environment
Background A micronucleus test is generally used to evaluate the genotoxic potential of chemicals. Exaggerated erythropoiesis, as occurs following bleeding, may induce an unexpected increase in micronucleus frequency.
Yuki Okada, Satsuki Chikura, Takafumi Kimoto, Takeshi Iijima   +3 more
doaj   +1 more source

Toxicology evaluation of selenium protein powder

BIO Web of Conferences, 2017
The experiment was conducted to evaluate the safety of selenium protein powder, a novel organic selenium nutritional supplement, and reported corresponding data and results based on a series of toxicological tests.
Qin Shunyi, Liu Lina, Wang Jingshen, Zhao Fanghong, Ma Jifei   +4 more
doaj   +1 more source

The Micronucleus Test as an in Vivo Cytogenetic Method

Environmental Health Perspectives, 1973
Methods are currently being explored which would permit the application of cytogenetic procedures such as metaphase and anaphase analyses to in vivo mammalian systems in order that due consideration may be given to metabolic activation or detoxification reactions which might affect the mutagenic or clastogenic (chromosome breaking) potential of ...
openaire   +2 more sources

Evaluation of the genotoxic potential of Austroplenckia populnea (Reiss) Lundell chloroform fraction from barkwood extract in rodent cells in vivo Avaliação do potencial genotóxico da fração clorofórmica de cascas do caule de Austroplenckia populnea em células de roedores in vivo

Brazilian Journal of Biology, 2009
The genotoxic effect of the Austroplenckia populnea chloroform fraction from barkwood extract was tested in vivo on peripheral blood cells of Swiss mice with the comet assay (SCGE), and the clastogenic effect was investigated on peripheral blood cells of
JC. Ribeiro, SF. Andrade, JK. Bastos, EL. Maistro   +3 more
doaj   +1 more source

Correlation between the results of in vitro and in vivo chromosomal damage tests in consideration of exposure levels of test chemicals

Genes and Environment, 2018
Introduction We examined the correlation between the results of in vitro and in vivo chromosomal damage tests by using in-house data of 18 pharmaceutical candidates that showed positive results in the in vitro chromosomal aberration or micronucleus test ...
Eiji Yamamura, Chinami Aruga, Shigeharu Muto, Nobuyuki Baba, Yoshifumi Uno   +4 more
doaj   +1 more source