The Micronucleus Test for Occupational Safety. [PDF]
Med LavAlthough less commonly used than internal dose indicators, biological effect indicators can be valuable for Risk Assessment. Among the numerous biomarkers used to date, those that indicate DNA damage could be especially useful for occupational safety, as they predict the risk of carcinogenesis.
Udroiu I, Giliberti C, Sgura A.
europepmc +4 more sources
Integrating Adaptive Responses Into Hormesis: δ Plot Analysis of the Yonezawa Effect in the Micronucleus Test [PDF]
Dose-ResponseObjectives Cells and organisms respond dynamically to environmental stimuli such as radiation and chemicals. Depending on the assay system, these responses have been described as hormesis, adaptive responses, J-shaped responses, and biphasic responses ...
Shizuyo Sutou +5 more
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Micronucleus test using formalin-fixed rat glandular stomach and colon [PDF]
Genes and Environment, 2023 Background Genotoxicity in tissues other than hematopoietic tissues, such as the liver and gastrointestinal (GI) tract, is an important focus in the risk assessment of chemicals in humans. We previously developed a rat micronucleus test for the GI tract,
Wakako Ohyama +4 more
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Citation: 'micronucleus test' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.10960 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
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Evaluating the Suitability of HepaRG Cells for Regulatory Micronucleus Testing: Comparing Results for a Diverse Set of 28 Chemicals to Regulatory Accepted TK6 Cells. [PDF]
Environ Mol MutagenAllemang A, Pfuhler S.
europepmc +2 more sources
Multiple Pesticides and their Mixtures Tested for Genotoxicity in the Micronucleus Assays on Intestinal Caco-2 Cells. [PDF]
Ann Glob HealthTruzzi F +12 more
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Is duration of exposure a determinant factor for genotoxicity and clinical manifestations induced by Formaldehyde? [PDF]
Ain Shams Journal of Forensic Medicine and Clinical Toxicology, 2021 Introduction: Formaldehyde is a naturally occurring compound extensively used as cadavers' preservative in medical schools anatomy departments. The International Agency for Research on Cancer (IARC) classifies formaldehyde as carcinogenic to humans ...
Elsayed Metwally +4 more
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Evaluation of genome stability of bone marrow cells of dogs with naturally infected visceral leishmaniasis [PDF]
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2023 The aim of this article is to identify and evaluate the genomic stability of visceral leishmaniasis in naturally infected dogs. A total of 32 dogs participated in the study, 24 of which were asymptomatic animals, naturally infected, and 8 uninfected ...
P.M.P. Silva +4 more
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Genotoxicity of Di (2-ethyl hexyl) phthalate
Zhongguo shipin weisheng zazhi, 2022 ObjectiveTo assess the genotoxicity of Di（2-ethylhexyl） phthalate （DEHP）.MethodsA series of guideline-compliant assays were performed to evaluate mutagenicity， chromosomal or DNA damage of DEHP， including Ames test， in vitro mammalian chromosome ...
LI Juntao +9 more
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Brazilian Oral Research, 2023 The aim of this systematic review was to evaluate published papers regarding the micronucleus assay in oral mucosal cells of patients undergoing orthodontic therapy (OT).
Daniel Vitor de SOUZA +5 more
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