Results 41 to 50 of about 2,848,619 (302)

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

The Cytogenetic Effects of Crude Ethanol Extracts of Petroselium Crspum Leaves on Bone Marrow In Mice (Mus Musculus) [PDF]

Engineering and Technology Journal, 2011
This study aimed to investigate the cytogenetic effects of ethanol extract of Petroselium crispum leaves on somatic cells of albino mice Mus musculus.Four doses (250,500,1000,2000)mgkg were used.Three tests,mitotic index,micronucleus formation and ...
doaj   +1 more source

PSYNDEX Tests Review für FTF-K - FRANKFURTER TESTS FÜR FÜNFJÄHRIGE - KONZENTRATION

, 1982
This is a PSYNDEX Tests Review of FTF-K - FRANKFURTER TESTS FÜR FÜNFJÄHRIGE - KONZENTRATION. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries. PSYNDEX Tests is
Raatz, Ulrich
core   +1 more source

Polyphenol‐Inspired Materials for Agricultural Applications

Advanced Materials, EarlyView.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu, Omid Mazaheri, Zhixing Lin, Tianzheng Wang, Jingqu Chen, Yuang Gu, Xia Liang, Deli Chen, Frank Caruso   +8 more
wiley   +1 more source

Guidance on aneugenicity assessment

EFSA Journal, 2021
The EFSA Scientific Committee was asked to provide guidance on the most appropriate in vivo tests to follow up on positive in vitro results for aneugenicity, and on the approach to risk assessment for substances that are aneugenic but not clastogenic nor
EFSA Scientific Committee (SC), Simon John More, Vasileios Bampidis, Claude Bragard, Thorhallur Ingi Halldorsson, Antonio F Hernández‐Jerez, Susanne Hougaard Bennekou, Kostas Koutsoumanis, Claude Lambré, Kyriaki Machera, Hanspeter Naegeli, Søren Saxmose Nielsen, Josef Schlatter, Dieter Schrenk, Dominique Turck, Maged Younes, Gabriele Aquilina, Margherita Bignami, Claudia Bolognesi, Riccardo Crebelli, Rainer Gürtler, Francesca Marcon, Elsa Nielsen, Christiane Vleminckx, Maria Carfì, Carla Martino, Daniela Maurici, Juan Parra Morte, Annamaria Rossi, Diane Benford   +29 more
doaj   +1 more source

Lymphocyte Micronucleus Formation Is Driven by Inflammation-Induced Oxidative DNA Damage in Oesophageal Cancer Development. [PDF]

Int J Cancer
Chromosomal instability is a hallmark of cancer, but minimally invasive ways to detect systemic DNA damage and cancer risk remain limited. Here, using patient blood samples, the authors investigated lymphocyte micronuclei (MN) frequency as a potential marker of DNA damage across the progression from gastroesophageal reflux disease to Barrett's ...
Munn K, Lawrence R, Haboubi H, Naser H, Hurlow K, Shah UK, Williams L, Gwynne S, Bodger O, Zavadil J, Virard F, Doak S, Thomas LE, Jenkins G.   +13 more
europepmc   +2 more sources

PSYNDEX Tests Review für RCT (1) - READING COMPREHENSION TESTS 1

, 1984
This is a PSYNDEX Tests Review of RCT (1) - READING COMPREHENSION TESTS 1. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Proekel, Gerhard
core   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

In vitro cytotoxic and genotoxic effects of newly synthesised boron ionic liquids

Biotechnology & Biotechnological Equipment, 2019
In this study, new molecules containing boron were added to the family of ionic organic compounds, in particular, ionic liquids with a cationic center. This study aimed to determine the cytotoxic and genetic effects of a total of four newly synthesised ...
Sibel Bayil Oguzkan, Hasan Turkez, Bora Karagul, Umit Cakir, Halil Ibrahim Ugras   +4 more
doaj   +1 more source

PSYNDEX Tests Review für ST-SM - Sporttest: Sportmotorische Tests für Mädchen

, 1986
This is a PSYNDEX Tests Review of ST-SM - Sporttest: Sportmotorische Tests für Mädchen. PSYNDEX Tests Reviews are written in German and describe and evaluate psychological and educational tests used in the German-speaking countries.
Waschler, Gerhard
core   +1 more source